edaravone has been researched along with Necrosis in 9 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to evaluate the protective effect of edaravone, a free radical scavenger, on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma." | 9.19 | Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial. ( Hu, W; Li, G; Luo, J; Rong, X; Tang, Y; Xu, P; Yang, J; Yang, X, 2014) |
| " This study was designed to evaluate the protective effect of edaravone, a free radical scavenger, on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma." | 5.19 | Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial. ( Hu, W; Li, G; Luo, J; Rong, X; Tang, Y; Xu, P; Yang, J; Yang, X, 2014) |
| "A rat intracerebral hemorrhage (ICH) model was established by combining FUS and microbubbles (μBs), and edaravone was used to verify whether the free radical scavenger had a protective effect on the model." | 4.31 | A new method for preparing a rat intracerebral hemorrhage model by combining focused ultrasound and microbubbles. ( He, Y; Hu, F; Li, Q; Li, X; Liao, M; Lu, Q; Mei, C; Nie, Y; Song, K; Wu, Z; Yang, J; Zhang, T; Zhong, Z; Zhu, X, 2023) |
| "Edaravone mainly showed a prophylactic effect on neurons against glutamate neurotoxicity, possibly through the inhibition of necrosis via the suppression of ROS production." | 3.75 | Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture. ( Hisano, K; Morimoto, Y; Watanabe, M, 2009) |
| "Fatty degeneration and necrosis with marked elevation of serum alanine aminotransferase and lactate dehydrogenase levels developed after CCl4 administration were significantly reduced by edaravone." | 3.72 | A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury. ( Ishii, H; Kameyama, K; Kitamura, K; Kurita, S; Nakamoto, N; Saito, H; Saito, Y; Tada, S, 2003) |
| "However, its effect on myocardial reperfusion injury after prolonged ischemia has not yet been demonstrated." | 1.29 | Effect of MCI-186 on postischemic reperfusion injury in isolated rat heart. ( Koide, S; Minhaz, U; Nakazawa, H; Shohtsu, A; Tanaka, M; Tsukamoto, H; Watanabe, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| He, Y | 1 |
| Yang, J | 2 |
| Hu, F | 1 |
| Liao, M | 1 |
| Nie, Y | 1 |
| Zhu, X | 1 |
| Zhang, T | 1 |
| Song, K | 1 |
| Li, Q | 1 |
| Li, X | 1 |
| Mei, C | 1 |
| Wu, Z | 1 |
| Lu, Q | 1 |
| Zhong, Z | 1 |
| Tang, Y | 1 |
| Rong, X | 1 |
| Hu, W | 1 |
| Li, G | 1 |
| Yang, X | 1 |
| Xu, P | 1 |
| Luo, J | 1 |
| Hisano, K | 1 |
| Watanabe, M | 3 |
| Morimoto, Y | 2 |
| Kikuchi, K | 1 |
| Uchikado, H | 1 |
| Miyagi, N | 1 |
| Ito, T | 1 |
| Tancharoen, S | 1 |
| Miura, N | 1 |
| Miyata, K | 1 |
| Sakamoto, R | 1 |
| Kikuchi, C | 1 |
| Iida, N | 1 |
| Shiomi, N | 1 |
| Kuramoto, T | 1 |
| Kawahara, K | 1 |
| Wu, TW | 1 |
| Zeng, LH | 1 |
| Wu, J | 1 |
| Fung, KP | 1 |
| Nakamoto, N | 1 |
| Tada, S | 1 |
| Kameyama, K | 1 |
| Kitamura, K | 1 |
| Kurita, S | 1 |
| Saito, Y | 1 |
| Saito, H | 1 |
| Ishii, H | 1 |
| Zhu, C | 1 |
| Wang, X | 1 |
| Huang, Z | 1 |
| Qiu, L | 1 |
| Xu, F | 1 |
| Vahsen, N | 1 |
| Nilsson, M | 1 |
| Eriksson, PS | 1 |
| Hagberg, H | 1 |
| Culmsee, C | 1 |
| Plesnila, N | 1 |
| Kroemer, G | 1 |
| Blomgren, K | 1 |
| Ikegami, E | 1 |
| Fukazawa, R | 1 |
| Kanbe, M | 1 |
| Abe, M | 1 |
| Kamisago, M | 1 |
| Hajikano, M | 1 |
| Katsube, Y | 1 |
| Ogawa, S | 1 |
| Minhaz, U | 1 |
| Tanaka, M | 1 |
| Tsukamoto, H | 1 |
| Watanabe, K | 1 |
| Koide, S | 1 |
| Shohtsu, A | 1 |
| Nakazawa, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis in Patients With Nasopharyngeal Carcinoma After Radiotherapy[NCT01865201] | Phase 2 | 154 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for edaravone and Necrosis
| Article | Year |
|---|---|
Beyond neurological disease: new targets for edaravone (Review).
Topics: Animals; Antipyrine; Apoptosis; Cardiovascular Diseases; Edaravone; Free Radical Scavengers; Free Ra | 2011 |
1 trial available for edaravone and Necrosis
| Article | Year |
|---|---|
Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antipyrine; Brain Injuries; Carcinoma; Case-Control Studies; Edaravo | 2014 |
7 other studies available for edaravone and Necrosis
| Article | Year |
|---|---|
A new method for preparing a rat intracerebral hemorrhage model by combining focused ultrasound and microbubbles.
Topics: Animals; Cerebral Hemorrhage; Cerebral Infarction; Edaravone; Microbubbles; Necrosis; Rats; Rats, Sp | 2023 |
Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture.
Topics: Animals; Antipyrine; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ed | 2009 |
Myocardial protection of MCI-186 in rabbit ischemia-reperfusion.
Topics: Animals; Antipyrine; Blood Pressure; Disease Models, Animal; Edaravone; Electrocardiography; Free Ra | 2002 |
A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Alanine Transaminase; Aldehydes; Animals; Antipyrine; Ap | 2003 |
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Antipyrine; Apoptosis; Apoptosis Inducin | 2007 |
Edaravone, a potent free radical scavenger, prevents anthracycline-induced myocardial cell death.
Topics: Animals; Anthracyclines; Antipyrine; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Daunorubi | 2007 |
Effect of MCI-186 on postischemic reperfusion injury in isolated rat heart.
Topics: Animals; Antioxidants; Antipyrine; Creatine Kinase; Edaravone; Free Radical Scavengers; Humans; In V | 1996 |