edaravone has been researched along with MELAS Syndrome in 2 studies
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the relationship between oxidative stress and progressive spread of the stroke-like lesions in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with 3243A>G mutation, we retrospectively analyzed the spread frequency in patients with and without treatment with the radical scavenger edaravone." | 3.75 | Accumulation of oxidative stress around the stroke-like lesions of MELAS patients. ( Hashizume, Y; Hayashi, M; Iizuka, T; Kashiwagi, A; Katayama, Y; Kawai, H; Maeda, K; Sanada, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katayama, Y | 1 |
| Maeda, K | 2 |
| Iizuka, T | 1 |
| Hayashi, M | 1 |
| Hashizume, Y | 1 |
| Sanada, M | 1 |
| Kawai, H | 2 |
| Kashiwagi, A | 1 |
| Tatsumi, M | 1 |
| Tahara, M | 1 |
| Murata, Y | 1 |
| Yasuda, H | 1 |
2 other studies available for edaravone and MELAS Syndrome
| Article | Year |
|---|---|
Accumulation of oxidative stress around the stroke-like lesions of MELAS patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Aged; Aged, 80 and over; Antipyrine; Deoxyguanosine; | 2009 |
[A case of stroke-like episode of MELAS of which progressive spread would be prevented by edaravone].
Topics: Adult; Antipyrine; Brain; Disease Progression; Edaravone; Female; Free Radical Scavengers; Humans; M | 2005 |