Page last updated: 2024-10-30

edaravone and Lung Injury, Acute

edaravone has been researched along with Lung Injury, Acute in 10 studies

Research Excerpts

ExcerptRelevanceReference
"In this study, we aimed to investigate the effects of diterpene ginkgolides meglumine injection (DGMI) on paraquat (PQ)-induced lung injury and pulmonary fibrosis in rats."7.88Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats. ( Li, GP; Li, L; Liu, Q; Wang, ZZ; Xiao, W; Xu, ZL; Yang, H; Zhou, J; Zong, SB, 2018)
" The present study aims to investigate the effects of edaravone on hyperoxia-induced oxidative injury and the underlying mechanism."7.81Edaravone protects rats and human pulmonary alveolar epithelial cells against hyperoxia injury: heme oxygenase-1 and PI3K/Akt pathway may be involved. ( Cao, H; Feng, Y; Li, Q; Li, W; Ning, Y; Zhang, Z, 2015)
"The present study aimed to investigate the combined effects of a neutrophil elastase inhibitor, sivelestat sodium, with a free radical scavenger, edaravone, on lipolysaccharide (LPS)-induced acute lung injury (ALI)."7.78Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats. ( Bao, R; Chen, H; Deng, X; Hou, J; Li, J; Liu, Y; Sun, L; Wang, J; Yang, T; Zhang, J; Zhu, X, 2012)
"Edaravone treatment significantly reduced the elevated malondialdehyde levels in rat lungs after acute pancreatitis, suggesting an important role for free radicals in acute pancreatitis-associated lung injury."5.36Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury. ( Cai, ZY; Deng, XM; Hou, J; Hu, JY; Liu, SQ; Mao, YF; Ni, X; Yang, T; Zhu, XY, 2010)
"In this study, we aimed to investigate the effects of diterpene ginkgolides meglumine injection (DGMI) on paraquat (PQ)-induced lung injury and pulmonary fibrosis in rats."3.88Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats. ( Li, GP; Li, L; Liu, Q; Wang, ZZ; Xiao, W; Xu, ZL; Yang, H; Zhou, J; Zong, SB, 2018)
" The present study aims to investigate the effects of edaravone on hyperoxia-induced oxidative injury and the underlying mechanism."3.81Edaravone protects rats and human pulmonary alveolar epithelial cells against hyperoxia injury: heme oxygenase-1 and PI3K/Akt pathway may be involved. ( Cao, H; Feng, Y; Li, Q; Li, W; Ning, Y; Zhang, Z, 2015)
"The present study aimed to investigate the combined effects of a neutrophil elastase inhibitor, sivelestat sodium, with a free radical scavenger, edaravone, on lipolysaccharide (LPS)-induced acute lung injury (ALI)."3.78Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats. ( Bao, R; Chen, H; Deng, X; Hou, J; Li, J; Liu, Y; Sun, L; Wang, J; Yang, T; Zhang, J; Zhu, X, 2012)
" In this study, we aimed to evaluate the protective effects of edaravone combined with dexamethasone on smoke-induced inhalational lung injury."1.62Edaravone combined with dexamethasone exhibits synergic effects on attenuating smoke-induced inhalation lung injury in rats. ( Chen, K; Guo, H; He, J; Li, H; Liu, J; Xiao, K; Yang, R; Yang, W, 2021)
"Edaravone treatment significantly reduced the elevated malondialdehyde levels in rat lungs after acute pancreatitis, suggesting an important role for free radicals in acute pancreatitis-associated lung injury."1.36Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury. ( Cai, ZY; Deng, XM; Hou, J; Hu, JY; Liu, SQ; Mao, YF; Ni, X; Yang, T; Zhu, XY, 2010)
"Edaravone was given by intraperitoneal administration 1 h before the LPS challenge."1.35Preventive effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced lung injury in mice. ( Bando, M; Enomoto, M; Gejyo, F; Ohno, S; Soda, M; Sugiyama, Y; Suzuki, E; Tajima, S; Takada, T; Yamasawa, H, 2008)
"Edaravone pretreatment reduced markedly the productions of ROS-HR and MDA and increased the activities of GSH-PX and SOD."1.35Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model. ( Chen, D; Chen, Y; Gu, H; Qiu, W; Zheng, L; Zhou, J, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Guo, H1
Yang, R1
He, J1
Chen, K1
Yang, W2
Liu, J1
Xiao, K1
Li, H1
Zhang, Z3
Luo, Z1
Bi, A1
An, W1
Dong, X1
Chen, R1
Yang, S1
Tang, H1
Han, X1
Luo, L1
Li, GP1
Yang, H1
Zong, SB1
Liu, Q1
Li, L1
Xu, ZL1
Zhou, J2
Wang, ZZ1
Xiao, W1
Wu, Z2
Ming, Y1
Wu, J1
Yao, S1
Uchiyama, M1
Tojo, K1
Yazawa, T1
Ota, S1
Goto, T1
Kurahashi, K1
Cao, H1
Feng, Y1
Ning, Y1
Li, W1
Li, Q1
Tajima, S1
Soda, M1
Bando, M1
Enomoto, M1
Yamasawa, H1
Ohno, S1
Takada, T1
Suzuki, E1
Gejyo, F1
Sugiyama, Y1
Qiu, W1
Gu, H1
Zheng, L1
Chen, D1
Chen, Y1
Yang, T2
Mao, YF1
Liu, SQ1
Hou, J2
Cai, ZY1
Hu, JY1
Ni, X1
Deng, XM1
Zhu, XY1
Zhang, J1
Sun, L1
Zhu, X1
Li, J1
Wang, J1
Chen, H1
Bao, R1
Deng, X1
Liu, Y1

Other Studies

10 other studies available for edaravone and Lung Injury, Acute

ArticleYear
Edaravone combined with dexamethasone exhibits synergic effects on attenuating smoke-induced inhalation lung injury in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blood Gas Analysis; B

2021
Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice.
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Acute Lung Injury; Animals; Antipyrine; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Cytokines; E

2017
Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Acute Lung Injury; Animals; Antipyrine; Dose-Response Relationship, Drug; Edaravone; Ginkgolides; In

2018
Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat model.
    Chinese medical journal, 2014, Volume: 127, Issue:5

    Topics: Acute Lung Injury; Animals; Antipyrine; Cytokines; Edaravone; Free Radical Scavengers; Lipid Peroxid

2014
Edaravone prevents lung injury induced by hepatic ischemia-reperfusion.
    The Journal of surgical research, 2015, Volume: 194, Issue:2

    Topics: Acute Lung Injury; Alanine Transaminase; Animals; Antipyrine; Aspartate Aminotransferases; Cytokines

2015
Edaravone protects rats and human pulmonary alveolar epithelial cells against hyperoxia injury: heme oxygenase-1 and PI3K/Akt pathway may be involved.
    Experimental lung research, 2015, Volume: 41, Issue:7

    Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Antioxidants; Antipyrine; Cell Survival; Cell

2015
Preventive effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced lung injury in mice.
    Respirology (Carlton, Vic.), 2008, Volume: 13, Issue:5

    Topics: Acute Lung Injury; Animals; Antipyrine; Cell Line; Chemokine CXCL2; Disease Models, Animal; Edaravon

2008
Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:11

    Topics: Acute Lung Injury; Animals; Animals, Suckling; Antipyrine; Constriction; Disease Models, Animal; Eda

2008
Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury.
    European journal of pharmacology, 2010, Mar-25, Volume: 630, Issue:1-3

    Topics: Acute Lung Injury; Animals; Antipyrine; Disease Models, Animal; Edaravone; Free Radical Scavengers;

2010
Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:6

    Topics: Acute Lung Injury; Animals; Antipyrine; Drug Combinations; Edaravone; Free Radical Scavengers; Glyci

2012