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edaravone and Ischemic Attack, Transient

edaravone has been researched along with Ischemic Attack, Transient in 10 studies

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"Edaravone was treated twice via tail vein; after MCA occlusion and after reperfusion."1.43A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model. ( Arai, K; Fujiwara, N; Lee, BJ; Lo, EH; Mandeville, ET; Pham, LD; Som, AT, 2016)
"Treatment with edaravone significantly increased the number of NSPCs and newly generated neurons in the subgranular zone (pā€‰<ā€‰."1.40Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats. ( Chen, X; Gao, M; He, X; Lei, S; Li, W; Li, X; Liu, Y; Lu, H; Qi, C; Wang, N; Wang, X; Zhang, J; Zhang, P; Zheng, J, 2014)
"Edaravone treatment significantly inhibited both lipid and DNA oxidative damage 72h after ischemia, and decreased neuronal damage."1.38Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils. ( Hirooka, K; Itano, T; Kawai, N; Keep, RF; Liu, Y; Lu, F; Miyamoto, O; Nakamura, T; Okabe, N; Shiraga, F; Tamiya, T; Toyoshima, T, 2012)
"A 68-year-old man with left cervical internal carotid artery stenosis suffered crescendo transient ischemic attacks caused by mobile thrombus detected by carotid echography and secondary impairment of cerebral hemodynamic reserve demonstrated by positron emission tomography."1.34Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is ( Inoue, T; Kobayashi, M; Komoribayashi, N; Ogasawara, K; Ogawa, A; Saito, H; Suga, Y, 2007)
"Pretreatment with edaravone but not post-treatment dose-dependently improved the response to high K+ but not the massive dopamine increase during ischemia."1.34Improvement of postischemic dopaminergic dysfunction by edaravone, a free radical scavenger. ( Akiyama, Y; Miwa, S, 2007)
"The volume of cerebral infarction, induced by 2-h occlusion and subsequent 2-h reperfusion of MCA in Fisher-344 rats, was evaluated."1.30Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat. ( Iwai, T; Nakashima, M; Niwa, M; Uematsu, T, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lei, S1
Zhang, P1
Li, W1
Gao, M1
He, X1
Zheng, J1
Li, X1
Wang, X1
Wang, N1
Zhang, J1
Qi, C1
Lu, H1
Chen, X1
Liu, Y2
Fujiwara, N1
Som, AT1
Pham, LD1
Lee, BJ1
Mandeville, ET1
Lo, EH1
Arai, K1
Liu, N1
Shang, J1
Tian, F1
Nishi, H1
Abe, K1
Yamamoto, Y1
Ohara, T1
Nagakane, Y1
Tanaka, E1
Morii, F1
Koizumi, T1
Lu, F1
Nakamura, T1
Toyoshima, T1
Hirooka, K1
Kawai, N1
Okabe, N1
Shiraga, F1
Tamiya, T1
Miyamoto, O1
Keep, RF1
Itano, T1
Ahmad, A1
Khan, MM1
Javed, H1
Raza, SS1
Ishrat, T1
Khan, MB1
Safhi, MM1
Islam, F1
Kobayashi, M1
Ogasawara, K1
Inoue, T1
Saito, H1
Komoribayashi, N1
Suga, Y1
Ogawa, A1
Akiyama, Y1
Miwa, S1
Xiao, B1
Bi, FF1
Hu, YQ1
Tian, FF1
Wu, ZG1
Mujlli, HM1
Ding, L1
Zhou, XF1
Nakashima, M1
Niwa, M1
Iwai, T1
Uematsu, T1

Reviews

1 review available for edaravone and Ischemic Attack, Transient

ArticleYear
[Concept of branch atheromatous disease (BAD) and its clinical significance].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Antipyrine; Arginine; Cerebral Infarction; Cilostazol; Drug Therapy, Combination; Edaravone; Humans;

2010

Other Studies

9 other studies available for edaravone and Ischemic Attack, Transient

ArticleYear
Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats.
    ASN neuro, 2014, Volume: 6, Issue:6

    Topics: Animals; Animals, Newborn; Antipyrine; Apoptosis; CA1 Region, Hippocampal; Cell Death; Cells, Cultur

2014
A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model.
    Neuroscience letters, 2016, 10-28, Volume: 633

    Topics: Animals; Antipyrine; Brain Edema; Cerebral Infarction; Cytokines; Edaravone; Free Radical Scavengers

2016
In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice.
    Brain research, 2011, Jun-23, Volume: 1397

    Topics: Animals; Annexin A5; Antipyrine; Apoptosis; Autophagy; Blood-Brain Barrier; Blotting, Western; Cereb

2011
Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils.
    Neuroscience letters, 2012, Jan-06, Volume: 506, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Antipyrine; Behavioral Symptoms; Deoxygu

2012
Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat.
    Molecular and cellular biochemistry, 2012, Volume: 367, Issue:1-2

    Topics: Animals; Antipyrine; Apoptosis; Basal Ganglia; Caspase 3; Choline O-Acetyltransferase; Cholinergic N

2012
Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:3

    Topics: Aged; Antipyrine; Carotid Stenosis; Edaravone; Endarterectomy, Carotid; Free Radical Scavengers; Hum

2007
Improvement of postischemic dopaminergic dysfunction by edaravone, a free radical scavenger.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:1

    Topics: Animals; Antipyrine; Corpus Striatum; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug

2007
Edaravone neuroprotection effected by suppressing the gene expression of the Fas signal pathway following transient focal ischemia in rats.
    Neurotoxicity research, 2007, Volume: 12, Issue:3

    Topics: Animals; Antipyrine; Death Domain Receptor Signaling Adaptor Proteins; Disease Models, Animal; DNA F

2007
Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat.
    Free radical biology & medicine, 1999, Volume: 26, Issue:5-6

    Topics: Animals; Antipyrine; Brain; Caudate Nucleus; Cerebral Infarction; Cyclic N-Oxides; Disease Models, A

1999