Page last updated: 2024-10-30

edaravone and Injuries, Spinal Cord

edaravone has been researched along with Injuries, Spinal Cord in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Edaravone is a scavenger of hydroxyl radicals."1.37Protective effects of edaravone on experimental spinal cord injury in rats. ( Altaş, M; Aras, M; Oran, I; Ozgiray, E; Oztürk, OH; Serarslan, Y; Söğüt, S; Yurtseven, T; Zileli, M, 2011)
"Pretreatment with edaravone significantly improved motor dysfunction and reduced the lesion volume to about 63% of the control (p < 0."1.35Edaravone (MCI-186) scavenges reactive oxygen species and ameliorates tissue damage in the murine spinal cord injury model. ( Aoyama, T; Hida, K; Iwasaki, Y; Kuroda, S; Seki, T; Shichinohe, H; Yano, S, 2008)
"Edaravone was administered intravenously as a bolus dose of 5 mg/kg at 5 minutes, 24 hours, and 48 hours after injury (edaravone-treated rats)."1.33Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats. ( Iwashita, Y; Kuno, S; Nakamura, T; Ohta, S; Takada, H, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Verma, S1
Lim, J1
Buscemi-Kimmins, T1
Brose, SW1
Xu, B1
Fang, J1
Wang, J2
Jin, X1
Liu, S2
Song, K1
Wang, P1
Liu, J1
Wang, XB1
Zhou, LY1
Chen, XQ1
Li, R1
Yu, BB1
Pan, MX1
Fang, L1
Li, J1
Cui, XJ1
Yao, M1
Lu, X1
Igasaki, S1
Suzuki, Y1
Sakai, N1
Takenouchi, A1
Shinohara, K1
Kanemoto, T1
Li, Y1
Liu, L1
Yu, Z1
Yu, Y1
Sun, B1
Xiao, C1
Luo, S1
Li, L1
Ishii, H1
Petrenko, AB1
Sasaki, M1
Satoh, Y1
Kamiya, Y1
Tobita, T1
Furutani, K1
Matsuhashi, M1
Kohno, T1
Baba, H1
Guo, G1
Wang, W1
Tang, Y1
Shun, J1
Zhou, X1
Zhang, P1
Song, YY1
Peng, CG1
Ye, XB1
Aoyama, T1
Hida, K1
Kuroda, S1
Seki, T1
Yano, S1
Shichinohe, H1
Iwasaki, Y1
Ohta, S2
Iwashita, Y2
Kakinoki, R1
Noguchi, T1
Nakamura, T2
Ozgiray, E1
Serarslan, Y1
Oztürk, OH1
Altaş, M1
Aras, M1
Söğüt, S1
Yurtseven, T1
Oran, I1
Zileli, M1
Takahashi, G1
Sakurai, M1
Abe, K1
Itoyama, Y1
Tabayashi, K1
Takada, H1
Kuno, S1

Reviews

1 review available for edaravone and Injuries, Spinal Cord

ArticleYear
[A case of surfer's myelopathy with serial imaging examination from early stage after onset].
    Rinsho shinkeigaku = Clinical neurology, 2020, Nov-27, Volume: 60, Issue:11

    Topics: Adolescent; Athletic Injuries; Diffusion Tensor Imaging; Edaravone; Female; Glycerol; Humans; Infusi

2020

Other Studies

12 other studies available for edaravone and Injuries, Spinal Cord

ArticleYear
Isolated pulmonary recovery in a veteran with late stage bulbar ALS following edaravone treatment and cessation.
    The journal of spinal cord medicine, 2022, Volume: 45, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Respiratory Insufficiency; Spinal Cord Injuries; V

2022
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Animals; Autophagy; Blood-Brain Barrier; Edaravone; Endothelial Cells; Humans; Necroptosis; Protein

2023
Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a protocol for a systematic review and meta-analysis.
    Systematic reviews, 2023, 09-26, Volume: 12, Issue:1

    Topics: Animals; Bayes Theorem; Disease Models, Animal; Edaravone; Humans; Meta-Analysis as Topic; Neuroprot

2023
Effects of Edaravone on Functional Recovery of a Rat Model with Spinal Cord Injury Through Induced Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like Cells.
    Cellular reprogramming, 2021, Volume: 23, Issue:1

    Topics: Animals; Cell Differentiation; Edaravone; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal S

2021
Free radical scavenger edaravone produces robust neuroprotection in a rat model of spinal cord injury.
    Brain research, 2018, 03-01, Volume: 1682

    Topics: 3,4-Methylenedioxyamphetamine; Analysis of Variance; Animals; Antipyrine; Cytokines; Disease Models,

2018
Effect of methylprednisolone and edaravone administration on spinal cord injury.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:20

    Topics: Animals; Antipyrine; bcl-X Protein; Caspase 3; Edaravone; Methylprednisolone; Rats; Rats, Sprague-Da

2013
Combination of edaravone and neural stem cell transplantation repairs injured spinal cord in rats.
    Genetics and molecular research : GMR, 2015, Dec-29, Volume: 14, Issue:4

    Topics: Animals; Antipyrine; Cell Differentiation; Cell Movement; Cell Survival; Edaravone; Female; Fluoresc

2015
Edaravone (MCI-186) scavenges reactive oxygen species and ameliorates tissue damage in the murine spinal cord injury model.
    Neurologia medico-chirurgica, 2008, Volume: 48, Issue:12

    Topics: Animals; Antipyrine; Drug Evaluation, Preclinical; Edaravone; Female; Free Radical Scavengers; Hindl

2008
Effects of continuous intravenous infusion of MCI-186 on functional recovery after spinal cord injury in rats.
    Journal of neurotrauma, 2011, Volume: 28, Issue:2

    Topics: Animals; Antipyrine; Disease Models, Animal; Drug Administration Schedule; Edaravone; Free Radical S

2011
Protective effects of edaravone on experimental spinal cord injury in rats.
    Pediatric neurosurgery, 2011, Volume: 47, Issue:4

    Topics: Animals; Antipyrine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Male; Methylprednis

2011
MCI-186 prevents spinal cord damage and affects enzyme levels of nitric oxide synthase and Cu/Zn superoxide dismutase after transient ischemia in rabbits.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:5

    Topics: Animals; Antipyrine; Biopsy, Needle; Disease Models, Animal; Edaravone; Immunohistochemistry; Inject

2003
Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats.
    Spine, 2005, May-15, Volume: 30, Issue:10

    Topics: Acute Disease; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hindlimb; Injections, Intrav

2005