Page last updated: 2024-10-30

edaravone and Hypoxia

edaravone has been researched along with Hypoxia in 13 studies

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
" This study investigated the effects of edaravone, a potent free radical scavenger, on intermittent hypoxia (IH)-induced oxidative damage and cognition impairment in a young rat model of IH."7.96Edaravone Improves Intermittent Hypoxia-Induced Cognitive Impairment and Hippocampal Damage in Rats. ( Duan, Y; Guo, T; Li, L; Li, Y; Ling, J; Liu, W; Wang, X; Yu, Q; Yuan, X, 2020)
"To investigate the mechanism of the pulmonary injury in rats caused by chronic intermittent hypoxia (CIH) and to investigate the intervention effect of Edaravone."7.81[The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone]. ( Kou, Y; Tan, X; Wang, H; Xie, B; Zhang, J; Zhang, M, 2015)
" This study investigated the effects of edaravone, a potent free radical scavenger, on intermittent hypoxia (IH)-induced oxidative damage and cognition impairment in a young rat model of IH."3.96Edaravone Improves Intermittent Hypoxia-Induced Cognitive Impairment and Hippocampal Damage in Rats. ( Duan, Y; Guo, T; Li, L; Li, Y; Ling, J; Liu, W; Wang, X; Yu, Q; Yuan, X, 2020)
"To investigate the mechanism of the pulmonary injury in rats caused by chronic intermittent hypoxia (CIH) and to investigate the intervention effect of Edaravone."3.81[The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone]. ( Kou, Y; Tan, X; Wang, H; Xie, B; Zhang, J; Zhang, M, 2015)
"Treatment with edaravone significantly increased the number of NSPCs and newly generated neurons in the subgranular zone (p < ."1.40Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats. ( Chen, X; Gao, M; He, X; Lei, S; Li, W; Li, X; Liu, Y; Lu, H; Qi, C; Wang, N; Wang, X; Zhang, J; Zhang, P; Zheng, J, 2014)
"In vivo, rat transient middle cerebral artery occlusion (MCAO) model was established."1.38Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model. ( Ding, XS; Gu, XS; Han, Q; Huang, H; Huang, HF; Liu, XF; Shen, LH; Wu, EB; Ye, M; Zhang, C, 2012)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Sánchez-González, C1
Herrero Martín, JC1
Salegi Ansa, B1
Núñez de Arenas, C1
Stančič, B1
Pereira, MP1
Contreras, L1
Cuezva, JM1
Formentini, L1
Ling, J1
Yu, Q1
Li, Y1
Yuan, X1
Wang, X3
Liu, W1
Guo, T1
Duan, Y1
Li, L1
Yamato, SH1
Nakamura, S1
Htun, Y1
Nakamura, M1
Jinnai, W1
Nakao, Y1
Mitsuie, T1
Koyano, K1
Wakabayashi, T1
Morimoto, AH1
Sugino, M1
Iwase, T1
Kondo, SI1
Yasuda, S1
Ueno, M1
Miki, T1
Kusaka, T1
Li, X2
Miao, L1
Guo, Y1
Yuan, R1
Tian, H1
Matsumoto, M1
Miyamoto, M1
Sawahata, M1
Izumi, Y1
Takada-Takatori, Y1
Kume, T1
Lei, S1
Zhang, P1
Li, W1
Gao, M1
He, X1
Zheng, J1
Wang, N1
Zhang, J2
Qi, C1
Lu, H1
Chen, X1
Liu, Y1
Kou, Y1
Xie, B1
Wang, H1
Tan, X1
Zhang, M1
Kaur, C2
Sivakumar, V2
Yip, GW1
Ling, EA2
Li, JJ1
Lu, J1
Wu, CY1
Martínez-Romero, R1
Cañuelo, A1
Martínez-Lara, E1
Javier Oliver, F1
Cárdenas, S1
Siles, E1
Shen, LH1
Ye, M1
Ding, XS1
Han, Q1
Zhang, C1
Liu, XF1
Huang, H1
Wu, EB1
Huang, HF1
Gu, XS1
Qi, X1
Okuma, Y1
Hosoi, T1
Nomura, Y1
Itoh, Y1
Takaoka, R1
Ohira, M1
Abe, T1
Tanahashi, N1
Suzuki, N1

Other Studies

13 other studies available for edaravone and Hypoxia

ArticleYear
Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates.
    Cell death & disease, 2022, 06-22, Volume: 13, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Edaravone; Humans; Hypoxia; Male; Mice; Mitochondrial Dyna

2022
Edaravone Improves Intermittent Hypoxia-Induced Cognitive Impairment and Hippocampal Damage in Rats.
    Biological & pharmaceutical bulletin, 2020, Aug-01, Volume: 43, Issue:8

    Topics: Animals; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-

2020
Intravenous Edaravone plus Therapeutic Hypothermia Offers Limited Neuroprotection in the Hypoxic-Ischaemic Newborn Piglet.
    Neonatology, 2020, Volume: 117, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Edaravone; Hypothermia, Induced; Hypoxia;

2020
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
    Biochemical and biophysical research communications, 2021, 06-04, Volume: 556

    Topics: Animals; Apoptosis; Benzofurans; Brain Ischemia; Cell Line; Cell Line, Tumor; Drug Design; Edaravone

2021
Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae.
    Journal of pharmacological sciences, 2021, Volume: 147, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cell Death; Disease Models, Animal; Dizocilpine Maleate; Drug Evalua

2021
Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats.
    ASN neuro, 2014, Volume: 6, Issue:6

    Topics: Animals; Animals, Newborn; Antipyrine; Apoptosis; CA1 Region, Hippocampal; Cell Death; Cells, Cultur

2014
[The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015, Volume: 29, Issue:19

    Topics: Angiotensin II; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hypoxia; Lung; Lung Injury;

2015
Expression of syndecan-2 in the amoeboid microglial cells and its involvement in inflammation in the hypoxic developing brain.
    Glia, 2009, Volume: 57, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Antipyrine; Cell Movement; Cells, Cultured; Corpus Callosum;

2009
Expression of angiotensin II and its receptors in the normal and hypoxic amoeboid microglial cells and murine BV-2 cells.
    Neuroscience, 2009, Feb-18, Volume: 158, Issue:4

    Topics: Angiotensin II; Animals; Animals, Newborn; Antibodies; Antipyrine; Cell Hypoxia; Cells, Cultured; Co

2009
Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF.
    Journal of neurochemistry, 2009, Volume: 111, Issue:1

    Topics: Analysis of Variance; Animals; Antipyrine; Brain; Disease Models, Animal; Edaravone; Enzyme Inhibito

2009
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipyrine; Brain; Brain Infarction; Brain-Derived

2012
Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Animals; Antipyrine; Apoptosis; Brain Ischemia; Cells, Cultured; Edaravone; Endoplasmic Reticulum; F

2004
Reactive oxygen species generated by mitochondrial injury in human brain microvessel endothelial cells.
    Clinical hemorheology and microcirculation, 2006, Volume: 34, Issue:1-2

    Topics: Antipyrine; Brain; Brain Ischemia; Cerebrovascular Circulation; Edaravone; Endothelium, Vascular; Fr

2006