edaravone has been researched along with Cardiovascular Stroke in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edaravone suppressed plasma MCP-1, improved left ventricular ejection fraction, and reduced rehospitalization due to heart failure." | 9.14 | Effect of edaravone on plasma monocyte chemoattractant protein-1 levels in patients with acute myocardial infarction. ( Chitose, T; Fukuda, M; Kaikita, K; Nagata, T; Nagayoshi, Y; Nakamura, Y; Nako, H; Ogawa, H; Ogura, Y; Ohba, K; Shimomura, H; Soejima, H; Sugiyama, S; Tsujita, K; Yamada, Y; Yamaguchi, M; Yamashita, T, 2009) |
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 9.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone." | 9.11 | Effects of edaravone on reperfusion injury in patients with acute myocardial infarction. ( Arai, H; Fukuda, M; Hida, S; Hokamaki, J; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2004) |
| "In the present study, we investigated whether combination therapy of low-dose benidipine with the potent free radical scavenger edaravone has a cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in Wistar rats." | 7.83 | Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2016) |
| "To explore the effect of edaravone on bone marrow mesenchymal stem cells (BMSCs) transplanted to treat acute myocardial infarction (AMI) and the underlying mechanism." | 7.83 | Edaravone promotes activation of resident cardiac stem cells by transplanted mesenchymal stem cells in a rat myocardial infarction model. ( Gu, TX; Li-Ling, J; Qi, X; Sun, XJ; Wang, C; Wang, XB; Zhang, GW, 2016) |
| "The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats." | 7.81 | Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015) |
| "Edaravone suppressed plasma MCP-1, improved left ventricular ejection fraction, and reduced rehospitalization due to heart failure." | 5.14 | Effect of edaravone on plasma monocyte chemoattractant protein-1 levels in patients with acute myocardial infarction. ( Chitose, T; Fukuda, M; Kaikita, K; Nagata, T; Nagayoshi, Y; Nakamura, Y; Nako, H; Ogawa, H; Ogura, Y; Ohba, K; Shimomura, H; Soejima, H; Sugiyama, S; Tsujita, K; Yamada, Y; Yamaguchi, M; Yamashita, T, 2009) |
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 5.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone." | 5.11 | Effects of edaravone on reperfusion injury in patients with acute myocardial infarction. ( Arai, H; Fukuda, M; Hida, S; Hokamaki, J; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2004) |
| "In the present study, we investigated whether combination therapy of low-dose benidipine with the potent free radical scavenger edaravone has a cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in Wistar rats." | 3.83 | Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2016) |
| "To explore the effect of edaravone on bone marrow mesenchymal stem cells (BMSCs) transplanted to treat acute myocardial infarction (AMI) and the underlying mechanism." | 3.83 | Edaravone promotes activation of resident cardiac stem cells by transplanted mesenchymal stem cells in a rat myocardial infarction model. ( Gu, TX; Li-Ling, J; Qi, X; Sun, XJ; Wang, C; Wang, XB; Zhang, GW, 2016) |
| "The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats." | 3.81 | Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, G | 1 |
| Sun, Y | 1 |
| Wang, Y | 1 |
| Li, X | 1 |
| Li, T | 1 |
| Su, S | 1 |
| Xu, L | 1 |
| Shen, H | 1 |
| Hassan, MQ | 2 |
| Akhtar, MS | 2 |
| Akhtar, M | 2 |
| Ali, J | 2 |
| Haque, SE | 2 |
| Najmi, AK | 2 |
| Zhang, GW | 1 |
| Gu, TX | 1 |
| Sun, XJ | 1 |
| Wang, C | 1 |
| Qi, X | 1 |
| Wang, XB | 1 |
| Li-Ling, J | 1 |
| Nakamura, Y | 3 |
| Yamada, Y | 1 |
| Shimomura, H | 3 |
| Nagayoshi, Y | 3 |
| Tsujita, K | 3 |
| Yamashita, T | 3 |
| Fukuda, M | 3 |
| Ohba, K | 1 |
| Nako, H | 1 |
| Ogura, Y | 1 |
| Chitose, T | 1 |
| Yamaguchi, M | 1 |
| Nagata, T | 1 |
| Soejima, H | 1 |
| Kaikita, K | 2 |
| Sugiyama, S | 1 |
| Ogawa, H | 3 |
| Rajesh, KG | 1 |
| Sasaguri, S | 1 |
| Suzuki, R | 1 |
| Maeda, H | 1 |
| Kawano, H | 2 |
| Hokamaki, J | 2 |
| Hida, S | 1 |
| Sakamoto, T | 2 |
| Yoshimura, M | 2 |
| Arai, H | 1 |
| Onimaru, S | 1 |
| Nakamura, K | 1 |
| Kariyazono, H | 1 |
| Ikeda, R | 1 |
| Ueno, T | 1 |
| Fukumoto, Y | 1 |
| Yabuki, A | 1 |
| Sakata, R | 1 |
| Yamada, K | 1 |
| Onogi, H | 1 |
| Minatoguchi, S | 1 |
| Chen, XH | 1 |
| Bao, N | 1 |
| Kobayashi, H | 1 |
| Misao, Y | 1 |
| Yasuda, S | 1 |
| Yamaki, T | 1 |
| Maruyama, R | 1 |
| Uno, Y | 1 |
| Arai, M | 1 |
| Takemura, G | 1 |
| Fujiwara, H | 1 |
3 trials available for edaravone and Cardiovascular Stroke
| Article | Year |
|---|---|
Effect of edaravone on plasma monocyte chemoattractant protein-1 levels in patients with acute myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Antipyrine; Biomarkers; Chemokine CCL2; Edaravone; Female; Fre | 2009 |
Effects of edaravone on reperfusion injury in patients with acute myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Antipyrine; Creatine Kinase; Creatine Kinase, MB Form; Edaravo | 2004 |
Long-term efficacy of edaravone in patients with acute myocardial infarction.
Topics: Acute Disease; Antipyrine; Arrhythmias, Cardiac; Edaravone; Free Radical Scavengers; Humans; Myocard | 2006 |
7 other studies available for edaravone and Cardiovascular Stroke
| Article | Year |
|---|---|
Local administration of lactic acid and a low dose of the free radical scavenger, edaravone, alleviates myocardial reperfusion injury in rats.
Topics: Animals; Antipyrine; Apoptosis; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers | 2013 |
Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence.
Topics: Animals; Antioxidants; Antipyrine; Apoptosis; C-Reactive Protein; Caspase 3; Creatine Kinase, MB For | 2015 |
Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage.
Topics: Animals; Antipyrine; Apoptosis; C-Reactive Protein; Calcium Channel Blockers; Caspase 3; Dihydropyri | 2016 |
Edaravone promotes activation of resident cardiac stem cells by transplanted mesenchymal stem cells in a rat myocardial infarction model.
Topics: Animals; Antipyrine; Apoptosis; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; E | 2016 |
Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antioxidants; Antipyrine; Atractyloside; Blo | 2003 |
Inhibitory effects of edaravone on the production of tumor necrosis factor-alpha in the isolated heart undergoing ischemia and reperfusion.
Topics: Analysis of Variance; Animals; Antipyrine; Blood Pressure; Blotting, Western; Edaravone; Free Radica | 2006 |
Edaravone reduces myocardial infarct size and improves cardiac function and remodelling in rabbits.
Topics: Animals; Antipyrine; Blood Pressure; Edaravone; Enzyme Inhibitors; Free Radical Scavengers; Gentisat | 2006 |