Page last updated: 2024-10-30

edaravone and Brain Infarction

edaravone has been researched along with Brain Infarction in 13 studies

Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.

Research Excerpts

ExcerptRelevanceReference
" In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the effect of edaravone which might reduce ischemic damage."9.15Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke. ( Nakase, T; Suzuki, A; Yoshioka, S, 2011)
"Edaravone improves the outcomes of patients with acute lacunar infarction, especially motor palsy, without regard to the conventional therapy performed concomitantly."7.75Efficacy of the free radical scavenger, edaravone, for motor palsy of acute lacunar infarction. ( Abe, K; Fukushima, T; Goto, K; Ikegami, S; Ohta, Y; Ota, T; Takamatsu, K; Takeda, I, 2009)
" In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the effect of edaravone which might reduce ischemic damage."5.15Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke. ( Nakase, T; Suzuki, A; Yoshioka, S, 2011)
"Edaravone improves the outcomes of patients with acute lacunar infarction, especially motor palsy, without regard to the conventional therapy performed concomitantly."3.75Efficacy of the free radical scavenger, edaravone, for motor palsy of acute lacunar infarction. ( Abe, K; Fukushima, T; Goto, K; Ikegami, S; Ohta, Y; Ota, T; Takamatsu, K; Takeda, I, 2009)
"Neurosyphilis is a chronic infection of the central nervous system that is commonly found in adult with long latency periods."1.51Young male with syphilitic cerebral arteritis presents with signs of acute progressive stroke: A case report. ( Li, Y; Pan, R; Shi, M; Yang, B; Yang, D; Zhong, L; Zhou, Y; Zhu, Y, 2019)
"In vivo, rat transient middle cerebral artery occlusion (MCAO) model was established."1.38Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model. ( Ding, XS; Gu, XS; Han, Q; Huang, H; Huang, HF; Liu, XF; Shen, LH; Wu, EB; Ye, M; Zhang, C, 2012)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, J2
Ling, J1
Wang, X1
Li, T1
Liu, J1
Lai, Y1
Ji, H1
Peng, S1
Tian, J1
Zhang, Y1
Shi, M1
Zhou, Y1
Li, Y1
Zhu, Y1
Yang, B1
Zhong, L1
Pan, R1
Yang, D1
Takahashi, S1
Inoue, Y1
Yabe, T1
Okada, K1
Nakamura, Y1
Ohta, Y1
Takamatsu, K1
Fukushima, T1
Ikegami, S1
Takeda, I1
Ota, T1
Goto, K1
Abe, K1
Isahaya, K1
Yamada, K1
Yamatoku, M1
Sakurai, K1
Takaishi, S1
Kato, B1
Hirayama, T1
Hasegawa, Y1
Nakase, T1
Yoshioka, S1
Suzuki, A1
Wadiwala, MF1
Sonawalla, A1
Kamal, AK1
Shen, LH1
Ye, M1
Ding, XS1
Han, Q1
Zhang, C1
Liu, XF1
Huang, H1
Wu, EB1
Huang, HF1
Gu, XS1
Mishina, M1
Komaba, Y1
Kobayashi, S1
Tanaka, N1
Kominami, S1
Fukuchi, T1
Mizunari, T1
Hamamoto, M1
Teramoto, A1
Katayama, Y1
Ueda, A1
Hashimoto, Y1
Kugimiya, F1
Yonemura, K1
Hirano, T1
Uchino, M1
Murakami, T1
Nakayasu, H1
Doi, M1
Fukada, Y1
Hayashi, M1
Suzuki, T1
Takeuchi, Y1
Nakashima, K1
Wu, TW1
Zeng, LH1
Fung, KP1

Trials

1 trial available for edaravone and Brain Infarction

ArticleYear
Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke.
    BMC neurology, 2011, Mar-30, Volume: 11

    Topics: Activities of Daily Living; Aged; Antipyrine; Brain Infarction; Diffusion Magnetic Resonance Imaging

2011

Other Studies

12 other studies available for edaravone and Brain Infarction

ArticleYear
Discovery of a potential anti-ischemic stroke agent: 3-pentylbenzo[c]thiophen-1(3H)-one.
    Journal of medicinal chemistry, 2012, Aug-23, Volume: 55, Issue:16

    Topics: Animals; Antioxidants; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Fibrinolytic Agents; Fr

2012
Young male with syphilitic cerebral arteritis presents with signs of acute progressive stroke: A case report.
    Medicine, 2019, Volume: 98, Issue:48

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; Brain Infarction; Clopidogrel; Edaravone; Humans; Mag

2019
[Treatment of acute ischemic stroke: tissue clock and reperfusion].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61 Suppl

    Topics: Acute Disease; Adult; Animals; Antipyrine; Brain Infarction; Edaravone; Free Radical Scavengers; Hum

2012
Effect of edaravone on acute brainstem-cerebellar infarction with vertigo and sudden hearing loss.
    Auris, nasus, larynx, 2014, Volume: 41, Issue:3

    Topics: Aged; Antipyrine; Brain Infarction; Brain Stem Infarctions; Cerebellum; Edaravone; Female; Free Radi

2014
Efficacy of the free radical scavenger, edaravone, for motor palsy of acute lacunar infarction.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:8

    Topics: Aged; Antipyrine; Brain Infarction; Edaravone; Female; Free Radical Scavengers; Humans; Male; Middle

2009
Effects of edaravone, a free radical scavenger, on serum levels of inflammatory biomarkers in acute brain infarction.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2012, Volume: 21, Issue:2

    Topics: Acute Disease; Aged; Aged, 80 and over; Analysis of Variance; Antipyrine; Biomarkers; Brain Infarcti

2012
What is the role of free radical scavengers in acute stroke?
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:5

    Topics: Acute Disease; Antipyrine; Biomarkers; Brain Infarction; Edaravone; Enzyme-Linked Immunosorbent Assa

2012
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipyrine; Brain; Brain Infarction; Brain-Derived

2012
Efficacy of edaravone, a free radical scavenger, for the treatment of acute lacunar infarction.
    Neurologia medico-chirurgica, 2005, Volume: 45, Issue:7

    Topics: Acute Disease; Aged; Antipyrine; Brain Infarction; Edaravone; Female; Free Radical Scavengers; Human

2005
[Bilateral multiple border zone infarctions after massive bleeding: report of two cases].
    Rinsho shinkeigaku = Clinical neurology, 2005, Volume: 45, Issue:10

    Topics: Aged; Anticoagulants; Antipyrine; Brain Infarction; Diffusion Magnetic Resonance Imaging; Edaravone;

2005
Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:10

    Topics: Acute Disease; Antipyrine; Aspirin; Basilar Artery; Brain Infarction; Cerebellar Diseases; Cerebellu

2006
MCI-186: further histochemical and biochemical evidence of neuroprotection.
    Life sciences, 2000, Sep-29, Volume: 67, Issue:19

    Topics: Animals; Antipyrine; Brain; Brain Infarction; Creatine Kinase; Cytochrome c Group; Edaravone; Free R

2000