edaravone has been researched along with Brain Hemorrhage, Cerebral in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to explore the influence of nanoparticle-loaded edaravone on postoperative effects in patients with cerebral hemorrhage, a total of 120 patients who were diagnosed as cerebral hemorrhage and underwent minimally invasive hematoma removal at the designated hospital by the study from December 2014 to December 2018 were selected as research objects and divided into three groups according to the random number table method: edaravone treatment (ET) group, nanoparticle-loaded edaravone treatment (NET) group, and combined treatment (CT) group with 40 patients in each group." | 8.02 | Influence of Nanoparticle-Loaded Edaravone on Postoperative Effects in Patients with Cerebral Hemorrhage. ( Dang, L; Dong, X; Yang, J, 2021) |
| "Edaravone is widely used for treating ischemic stroke, but it is not still confirmed in intracerebral hemorrhage (ICH) as an ideal medication targeting the brain parenchyma." | 7.83 | Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat. ( Gao, M; Ge, GZ; Ji, XC; Sun, YL; Wang, QQ; Xu, RX; Yang, Y; Zhang, GZ; Zhang, HT; Zhang, Y, 2016) |
| "In present study, we evaluated acute neuroprotective effects of combined therapy with pharmacologically induced hypothermia and edaravone in a rat model of intracerebral hemorrhage (ICH)." | 7.81 | Early Combined Therapy with Pharmacologically Induced Hypothermia and Edaravone Exerts Neuroprotective Effects in a Rat Model of Intracerebral Hemorrhage. ( Liu, C; Sun, Z; Zhu, Y, 2015) |
| "Edaravone attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia." | 7.80 | Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. ( Johshita, H; Miyazaki, H; Okamura, K; Shiokawa, Y; Tsubokawa, T, 2014) |
| "To explore the effects of edaravone on the expression of matrix metalloproteinase-9 (MMP-9) posterior to cerebral hemorrhage, and to analyze the relationship between this expression and neurological deficit." | 7.80 | Beneficial effects of edaravone on the expression of serum matrix metalloproteinase-9 after cerebral hemorrhage. ( Liu, Z; Zhao, F, 2014) |
| " In the first, the dose-dependent effects of edaravone on ICH-induced brain injury were examined by measuring brain edema and neurologic deficits." | 7.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| " The present study was undertaken to examine whether or not the free radical scavenger, edaravone, could prevent the extravasation of tPA administered for the purpose of fibrinolysis in a rat model of thromboembolic stroke." | 7.73 | Attenuation of extravasation of tissue plasminogen activator by the free radical scavenger, edaravone: evaluation in a rat thromboembolic stroke model. ( Harada, T; Kano, T; Katayama, Y, 2005) |
| "Edaravone has showed its neuroprotective effects after ischemia stroke, but its effects and possible mechanisms after ICH are poorly understood." | 5.56 | Edaravone Administration Confers Neuroprotection after Experimental Intracerebral Hemorrhage in Rats via NLRP3 Suppression. ( Geng, J; Jiang, Y; Miao, H; Tang, J; Zhang, B; Zhu, G, 2020) |
| "A rat intracerebral hemorrhage (ICH) model was established by combining FUS and microbubbles (μBs), and edaravone was used to verify whether the free radical scavenger had a protective effect on the model." | 4.31 | A new method for preparing a rat intracerebral hemorrhage model by combining focused ultrasound and microbubbles. ( He, Y; Hu, F; Li, Q; Li, X; Liao, M; Lu, Q; Mei, C; Nie, Y; Song, K; Wu, Z; Yang, J; Zhang, T; Zhong, Z; Zhu, X, 2023) |
| "In order to explore the influence of nanoparticle-loaded edaravone on postoperative effects in patients with cerebral hemorrhage, a total of 120 patients who were diagnosed as cerebral hemorrhage and underwent minimally invasive hematoma removal at the designated hospital by the study from December 2014 to December 2018 were selected as research objects and divided into three groups according to the random number table method: edaravone treatment (ET) group, nanoparticle-loaded edaravone treatment (NET) group, and combined treatment (CT) group with 40 patients in each group." | 4.02 | Influence of Nanoparticle-Loaded Edaravone on Postoperative Effects in Patients with Cerebral Hemorrhage. ( Dang, L; Dong, X; Yang, J, 2021) |
| "Edaravone is widely used for treating ischemic stroke, but it is not still confirmed in intracerebral hemorrhage (ICH) as an ideal medication targeting the brain parenchyma." | 3.83 | Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat. ( Gao, M; Ge, GZ; Ji, XC; Sun, YL; Wang, QQ; Xu, RX; Yang, Y; Zhang, GZ; Zhang, HT; Zhang, Y, 2016) |
| "In present study, we evaluated acute neuroprotective effects of combined therapy with pharmacologically induced hypothermia and edaravone in a rat model of intracerebral hemorrhage (ICH)." | 3.81 | Early Combined Therapy with Pharmacologically Induced Hypothermia and Edaravone Exerts Neuroprotective Effects in a Rat Model of Intracerebral Hemorrhage. ( Liu, C; Sun, Z; Zhu, Y, 2015) |
| "Edaravone attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia." | 3.80 | Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. ( Johshita, H; Miyazaki, H; Okamura, K; Shiokawa, Y; Tsubokawa, T, 2014) |
| "To explore the effects of edaravone on the expression of matrix metalloproteinase-9 (MMP-9) posterior to cerebral hemorrhage, and to analyze the relationship between this expression and neurological deficit." | 3.80 | Beneficial effects of edaravone on the expression of serum matrix metalloproteinase-9 after cerebral hemorrhage. ( Liu, Z; Zhao, F, 2014) |
| "We demonstrate that edaravone inhibits rtPA-induced cerebral hemorrhage in the ischemic brain of rats via the inhibition of MMP-9 expression in vivo, which is substantiated by inhibition of MMP-9 expression and NF-kappaB activation in HBECs." | 3.75 | Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. ( Kinouchi, T; Kitazato, KT; Nagahiro, S; Shimada, K; Tada, Y; Uno, M; Yagi, K, 2009) |
| " In the first, the dose-dependent effects of edaravone on ICH-induced brain injury were examined by measuring brain edema and neurologic deficits." | 3.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| " The present study was undertaken to examine whether or not the free radical scavenger, edaravone, could prevent the extravasation of tPA administered for the purpose of fibrinolysis in a rat model of thromboembolic stroke." | 3.73 | Attenuation of extravasation of tissue plasminogen activator by the free radical scavenger, edaravone: evaluation in a rat thromboembolic stroke model. ( Harada, T; Kano, T; Katayama, Y, 2005) |
| "Edaravone has showed its neuroprotective effects after ischemia stroke, but its effects and possible mechanisms after ICH are poorly understood." | 1.56 | Edaravone Administration Confers Neuroprotection after Experimental Intracerebral Hemorrhage in Rats via NLRP3 Suppression. ( Geng, J; Jiang, Y; Miao, H; Tang, J; Zhang, B; Zhu, G, 2020) |
| " While several trials in the last 8 years have reported the favourable long-term functional outcomes, a few reports indicated edaravone to be associated with an increase in adverse events." | 1.56 | Efficacy and safety of edaravone for acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis. ( Feng, L; Gao, Y; Guo, S; Jiang, P; Li, T; Liang, N; Yang, Q; Zhang, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 6 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Hua, Y | 1 |
| Zhou, L | 1 |
| Yang, W | 1 |
| An, W | 1 |
| Kou, X | 1 |
| Ren, J | 1 |
| Su, H | 1 |
| Chen, R | 1 |
| Zhang, Z | 1 |
| Zou, J | 1 |
| Zhao, Z | 1 |
| He, Y | 1 |
| Yang, J | 3 |
| Hu, F | 1 |
| Liao, M | 1 |
| Nie, Y | 1 |
| Zhu, X | 1 |
| Zhang, T | 1 |
| Song, K | 1 |
| Li, Q | 1 |
| Li, X | 1 |
| Mei, C | 1 |
| Wu, Z | 1 |
| Lu, Q | 1 |
| Zhong, Z | 1 |
| Cao, S | 1 |
| Wei, J | 1 |
| Cai, Y | 1 |
| Xiong, Z | 1 |
| Li, J | 1 |
| Jiang, Z | 1 |
| Zhou, X | 1 |
| Huang, B | 1 |
| Zeng, J | 1 |
| Miao, H | 1 |
| Jiang, Y | 1 |
| Geng, J | 1 |
| Zhang, B | 1 |
| Zhu, G | 2 |
| Tang, J | 1 |
| Feng, L | 1 |
| Liang, N | 1 |
| Li, T | 1 |
| Yang, Q | 1 |
| Jiang, P | 1 |
| Guo, S | 1 |
| Zhang, C | 1 |
| Gao, Y | 1 |
| Dang, L | 1 |
| Dong, X | 1 |
| Okamura, K | 1 |
| Tsubokawa, T | 1 |
| Johshita, H | 1 |
| Miyazaki, H | 1 |
| Shiokawa, Y | 1 |
| Chen, Z | 1 |
| Zhang, J | 2 |
| Chen, Q | 1 |
| Guo, J | 1 |
| Feng, H | 1 |
| Zhao, F | 1 |
| Liu, Z | 1 |
| Zhu, Y | 1 |
| Liu, C | 1 |
| Sun, Z | 1 |
| Zhang, Y | 1 |
| Yang, Y | 1 |
| Zhang, GZ | 1 |
| Gao, M | 1 |
| Ge, GZ | 1 |
| Wang, QQ | 1 |
| Ji, XC | 1 |
| Sun, YL | 1 |
| Zhang, HT | 1 |
| Xu, RX | 1 |
| Mishina, M | 1 |
| Komaba, Y | 1 |
| Kobayashi, S | 1 |
| Kominami, S | 1 |
| Fukuchi, T | 1 |
| Mizunari, T | 1 |
| Teramoto, A | 1 |
| Katayama, Y | 3 |
| Han, N | 1 |
| Ding, SJ | 1 |
| Wu, T | 1 |
| Zhu, YL | 1 |
| Yagi, K | 1 |
| Kitazato, KT | 1 |
| Uno, M | 1 |
| Tada, Y | 1 |
| Kinouchi, T | 1 |
| Shimada, K | 1 |
| Nagahiro, S | 1 |
| Yamashita, T | 1 |
| Kamiya, T | 1 |
| Deguchi, K | 1 |
| Inaba, T | 1 |
| Zhang, H | 1 |
| Shang, J | 1 |
| Miyazaki, K | 1 |
| Ohtsuka, A | 1 |
| Abe, K | 1 |
| Zhou, F | 1 |
| Chen, G | 1 |
| Liu, M | 1 |
| Zhou, J | 1 |
| Zhang, S | 1 |
| Lin, S | 1 |
| Zhao, H | 1 |
| Kano, T | 1 |
| Harada, T | 1 |
| Nakamura, T | 1 |
| Kuroda, Y | 1 |
| Yamashita, S | 1 |
| Zhang, X | 1 |
| Miyamoto, O | 1 |
| Tamiya, T | 1 |
| Nagao, S | 1 |
| Xi, G | 1 |
| Keep, RF | 1 |
| Itano, T | 1 |
1 review available for edaravone and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Edaravone for acute intracerebral haemorrhage.
Topics: Antipyrine; Cerebral Hemorrhage; Edaravone; Free Radical Scavengers; Humans; Randomized Controlled T | 2011 |
18 other studies available for edaravone and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Y-2 reduces oxidative stress and inflammation and improves neurological function of collagenase-induced intracerebral hemorrhage rats.
Topics: Animals; Brain Edema; Camphanes; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Drug Com | 2021 |
A new method for preparing a rat intracerebral hemorrhage model by combining focused ultrasound and microbubbles.
Topics: Animals; Cerebral Hemorrhage; Cerebral Infarction; Edaravone; Microbubbles; Necrosis; Rats; Rats, Sp | 2023 |
Network Pharmacology Prediction and Experimental Verification for Anti-Ferroptosis of Edaravone After Experimental Intracerebral Hemorrhage.
Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Cyclooxygenase 2; Edaravone; Hemin; Mitogen-Activated | 2023 |
Edaravone Administration Confers Neuroprotection after Experimental Intracerebral Hemorrhage in Rats via NLRP3 Suppression.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Brain; Caspase 1; Cerebral Hemorrhage; Disease | 2020 |
Efficacy and safety of edaravone for acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis.
Topics: Cerebral Hemorrhage; China; Data Management; Edaravone; Humans; Meta-Analysis as Topic; Treatment Ou | 2020 |
Influence of Nanoparticle-Loaded Edaravone on Postoperative Effects in Patients with Cerebral Hemorrhage.
Topics: Brain; Cerebral Hemorrhage; Edaravone; Free Radical Scavengers; Humans; Interleukins; Nanoparticles; | 2021 |
Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia.
Topics: Animals; Antipyrine; Blood Glucose; Brain; Cerebral Hemorrhage; Cerebral Infarction; Edaravone; Free | 2014 |
Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.
Topics: Animals; Antipyrine; Brain Edema; Cerebral Hemorrhage; Cognition Disorders; Edaravone; Free Radical | 2014 |
Beneficial effects of edaravone on the expression of serum matrix metalloproteinase-9 after cerebral hemorrhage.
Topics: Adult; Aged; Antipyrine; Cerebral Hemorrhage; Edaravone; Female; Free Radical Scavengers; Glasgow Co | 2014 |
Early Combined Therapy with Pharmacologically Induced Hypothermia and Edaravone Exerts Neuroprotective Effects in a Rat Model of Intracerebral Hemorrhage.
Topics: Animals; Antipyrine; Apoptosis Regulatory Proteins; Blood-Brain Barrier; Blotting, Western; Brain Ed | 2015 |
Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat.
Topics: Animals; Antipyrine; Apoptosis; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Collagenases; | 2016 |
Administration of free radical scavenger edaravone associated with higher frequency of hemorrhagic transformation in patients with cardiogenic embolism.
Topics: Aged; Aged, 80 and over; Antipyrine; Cerebral Hemorrhage; Dose-Response Relationship, Drug; Edaravon | 2008 |
Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats.
Topics: Analysis of Variance; Animals; Antipyrine; Apoptosis; Cerebral Hemorrhage; Disease Models, Animal; D | 2008 |
Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
Topics: Animals; Antipyrine; Blood Pressure; Blotting, Western; Brain Ischemia; Cells, Cultured; Cerebral He | 2009 |
Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain.
Topics: Animals; Antipyrine; Basement Membrane; Brain Ischemia; Cerebral Hemorrhage; Edaravone; Free Radical | 2009 |
Edaravone reduces brain oedema and attenuates cell death after intracerebral haemorrhage in mice.
Topics: Animals; Antipyrine; Brain; Brain Edema; Cell Death; Cerebral Hemorrhage; Collagenases; Disease Mode | 2009 |
Attenuation of extravasation of tissue plasminogen activator by the free radical scavenger, edaravone: evaluation in a rat thromboembolic stroke model.
Topics: Analysis of Variance; Animals; Antipyrine; Blood Vessels; Cerebral Hemorrhage; Disease Models, Anima | 2005 |
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
Topics: Acute Disease; Animals; Antipyrine; Basal Ganglia; Brain Edema; Cerebral Cortex; Cerebral Hemorrhage | 2008 |