Page last updated: 2024-10-30

edaravone and Anoxia, Brain

edaravone has been researched along with Anoxia, Brain in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, reduces brain edema in patients with acute ischemic stroke."3.74Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia. ( Imaizumi, T; Ishikawa, A; Matsumiya, T; Metoki, N; Satoh, K; Taima, K; Toki, T; Yamashita, K; Yoshida, H, 2007)
"Pretreatment with edaravone can prevent development of cognitive impairment after CEA."2.71Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy. ( Endo, H; Fukuda, T; Inoue, T; Kobayashi, M; Ogasawara, K; Ogawa, A; Terasaki, K; Yamadate, K; Yoshida, K, 2005)
"Edaravone treatment (3mg/kg, i."1.40A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion. ( Arai, K; Liang, AC; Maki, T; Miyamoto, N; Pham, LD, 2014)
"Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion."1.33Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyamoto, N1
Pham, LD1
Maki, T1
Liang, AC1
Arai, K1
Somekawa-Kondo, T1
Yamaguchi, K1
Ishitsuka, Y1
Ito, S1
Tanaka, K1
Irikura, M1
Moriuchi, H1
Takahama, K1
Ando, Y1
Yamazaki, T1
Irie, T1
Lee, JH1
Park, SY1
Lee, WS1
Hong, KW1
Ogasawara, K1
Yamadate, K1
Kobayashi, M1
Endo, H1
Fukuda, T1
Yoshida, K1
Terasaki, K1
Inoue, T1
Ogawa, A1
Ishikawa, A1
Yoshida, H1
Metoki, N1
Toki, T1
Imaizumi, T1
Matsumiya, T1
Yamashita, K1
Taima, K1
Satoh, K1

Trials

1 trial available for edaravone and Anoxia, Brain

ArticleYear
Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy.
    Surgical neurology, 2005, Volume: 64, Issue:4

    Topics: Aged; Antipyrine; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Cerebrovascular C

2005

Other Studies

4 other studies available for edaravone and Anoxia, Brain

ArticleYear
A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion.
    Neuroscience letters, 2014, Jun-24, Volume: 573

    Topics: Animals; Antipyrine; Blood-Brain Barrier; Carotid Artery, Common; Carotid Stenosis; Cell Death; Cell

2014
Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:1

    Topics: Aminophylline; Animals; Antipyrine; CA1 Region, Hippocampal; Creatine Kinase, BB Form; Disease Model

2013
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
    Neurological research, 2005, Volume: 27, Issue:5

    Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede

2005
Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia.
    Neuroscience research, 2007, Volume: 59, Issue:4

    Topics: Antipyrine; Astrocytes; Blood-Brain Barrier; Brain Edema; Cell Nucleus; Cells, Cultured; Cerebral Ar

2007