Page last updated: 2024-10-30

edaravone and Alloxan Diabetes

edaravone has been researched along with Alloxan Diabetes in 12 studies

Research Excerpts

ExcerptRelevanceReference
"Treatment with edaravone (3 and 10 mg/kg) significantly diminished the cerebral infarct, oedema volume and improved functional recovery of neurological deficits."5.38Edaravone offers neuroprotection in a diabetic stroke model via inhibition of endoplasmic reticulum stress. ( Sharma, SS; Srinivasan, K, 2012)
"Edaravone was given once-daily and was intraperitoneally (i."1.40Edaravone protect against retinal damage in streptozotocin-induced diabetic mice. ( Chen, X; Hang, H; Lin, X; Liu, Q; Liu, X; Xie, P; Xu, Y; Yuan, D; Yuan, S; Zhang, W, 2014)
"Treatment with edaravone (3 and 10 mg/kg) significantly diminished the cerebral infarct, oedema volume and improved functional recovery of neurological deficits."1.38Edaravone offers neuroprotection in a diabetic stroke model via inhibition of endoplasmic reticulum stress. ( Sharma, SS; Srinivasan, K, 2012)
"Edaravone or taurine treatment prevented significantly the decreased body, testicular, and epididymal weight induced by diabetes."1.38Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat. ( Dimitriadis, F; Koukos, S; Saito, M; Satoh, K; Shimizu, S; Sofikitis, N; Takenaka, A; Tsounapi, P, 2012)
"Treatment with edaravone prevented partially but significantly the decreased body and penile weight induced by diabetes."1.37Edaravone ameliorates diabetes-induced dysfunction of NO-induced relaxation in corpus cavernosum smooth muscle in the rat. ( Dimitriadis, F; Inoue, S; Kinoshita, Y; Ohmasa, F; Saito, M; Satoh, K; Shimizu, S; Shomori, K; Tsounapi, P, 2011)
"Edaravone is a potent scavenger of hydroxyl radicals and attenuates oxidative damage-related neurodegenerative diseases."1.35The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice. ( Ago, Y; Fukudome, D; Kawasaki, T; Matsuda, M; Matsuda, T, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's8 (66.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Wang, L1
Zeng, YQ1
Gu, JH1
Song, R1
Cang, PH1
Xu, YX1
Shao, XX1
Pu, LJ1
Luo, HY1
Zhou, XF1
Wan, YJ1
Hu, L1
Wang, XM1
Yuan, D1
Xu, Y1
Hang, H1
Liu, X1
Chen, X1
Xie, P1
Yuan, S1
Zhang, W1
Lin, X1
Liu, Q1
Ji, L1
Liu, Y1
Zhang, Y1
Chang, W1
Gong, J1
Wei, S1
Li, X1
Qin, L1
Tsounapi, P3
Honda, M1
Dimitriadis, F3
Shimizu, S3
Shiomi, T1
Hikita, K1
Saito, M3
Tomita, S1
Sofikitis, N2
Takenaka, A2
Nagatani, S1
Sudo, T1
Murakami, Y1
Uemura, K1
Hiyama, E1
Sueda, T1
Ohmasa, F1
Inoue, S1
Shomori, K1
Kinoshita, Y1
Satoh, K2
Srinivasan, K1
Sharma, SS3
Koukos, S1
Saini, AK2
Patel, RJ1
H S, AK1
Kumar H S, A1
Fukudome, D1
Matsuda, M1
Kawasaki, T1
Ago, Y1
Matsuda, T1

Other Studies

12 other studies available for edaravone and Alloxan Diabetes

ArticleYear
Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway.
    European journal of pharmacology, 2022, Apr-05, Volume: 920

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Edaravone; NF-E2-Rel

2022
Edaravone protects from retinal injury through NF-κB in diabetic rats.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:3 Suppl

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Edaravone; Interleukin

2019
Edaravone protect against retinal damage in streptozotocin-induced diabetic mice.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Antipyrine; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Edara

2014
The antioxidant edaravone prevents cardiac dysfunction by suppressing oxidative stress in type 1 diabetic rats and in high-glucose-induced injured H9c2 cardiomyoblasts.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:9

    Topics: Animals; Antioxidants; Antipyrine; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Prot

2016
Antioxidant treatment ameliorates diabetes-induced dysfunction of the vas deferens in a rat model.
    Andrologia, 2018, Volume: 50, Issue:1

    Topics: Animals; Antioxidants; Antipyrine; Diabetes Mellitus, Experimental; Edaravone; Male; Malondialdehyde

2018
Edaravone, a free radical scavenger, promotes engraftment of intraportally transplanted islet cells.
    Pancreas, 2011, Volume: 40, Issue:1

    Topics: Animals; Antipyrine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Edaravone; Free Ra

2011
Edaravone ameliorates diabetes-induced dysfunction of NO-induced relaxation in corpus cavernosum smooth muscle in the rat.
    The journal of sexual medicine, 2011, Volume: 8, Issue:6

    Topics: Animals; Antipyrine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Edaravone; Free Rad

2011
Edaravone offers neuroprotection in a diabetic stroke model via inhibition of endoplasmic reticulum stress.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Animals; Antipyrine; Apoptosis; Caspase 12; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type

2012
Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.
    Molecular and cellular biochemistry, 2012, Volume: 369, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Antipyrine; Deoxyguanosine; Diabetes Complicatio

2012
Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats.
    Pharmacological research, 2006, Volume: 54, Issue:1

    Topics: Angiotensin II; Animals; Antipyrine; Aorta, Thoracic; Blood Pressure; Catalase; Diabetes Mellitus, E

2006
Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy.
    European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3

    Topics: Animals; Antipyrine; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Edaravone; Fr

2007
The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Animals; Antipyrine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Edar

2008