edaravone has been researched along with Acute Disease in 27 studies
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study observed the effects of edaravone combined with Dl-3-N-butylphthalide (NBP) on the serum levels of tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), and neuron-specific enolase (NSE), and its therapeutic effect in patients with acute cerebral infarction (ACI)." | 9.51 | The effect of edaravone combined with DL-3-N-butylphthalide on the levels of tumor necrosis factor-alpha, interleukin-10, neuron-specific enolase and effect in patients with acute cerebral infarction. ( Shen, QQ; Tong, XW; Wang, W; Wu, H, 2022) |
| " Whether it can provide better outcomes when combined with edaravone injection (ERI) for the treatment of acute cerebral infarction is not well determined." | 9.41 | Edaravone combined with Shuxuening versus edaravone alone in the treatment of acute cerebral infarction: A systematic review and meta-analysis. ( Li, LD; Shi, SF; Zhou, Y, 2023) |
| "Our study aimed to investigate the effect of intravenous thrombolysis with alteplase and edaravone on cerebral hemodynamics and T lymphocyte level in patients harboring acute cerebral infarction." | 9.34 | Effects of intravenous thrombolysis with alteplase combined with edaravone on cerebral hemodynamics and T lymphocyte level in patients with acute cerebral infarction. ( Guo, SF; Li, XX; Liu, SH; Pang, SL; Zhuang, SJ, 2020) |
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 9.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "The efficacy of hyperbaric oxygen (HBO) therapy combined with intravenous edaravone (free radical scavenger) administration was prospectively investigated in patients with acute embolic stroke involving the anterior cerebral circulation." | 9.12 | Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial. ( Imai, K; Izumoto, H; Kunieda, T; Mori, T; Takabatake, N; Watanabe, M, 2006) |
| "To investigate the clinical efficacy and safety of Shenxiong glucose injection combined with edaravone in the treatment of acute large-area cerebral infarction." | 8.02 | A Single-Center Clinical Study to Evaluate Shenxiong Glucose Injection Combined with Edaravone in the Treatment of Acute Large-Area Cerebral Infarction. ( Huang, P; Li, Z; Luo, J; Rong, X; Xu, X; Zeng, T, 2021) |
| "To investigate the effects of penehyclidine combined with edaravone on acute cerebral infarction (ACI) in rats." | 7.88 | Curative efficacy of penehyclidine combined with edaravone on acute cerebral infarction and their effects on serum TNF-α and NDS score in rats. ( Chen, Y; Zhao, Y, 2018) |
| " Edaravone induced a decrease in blood flow in the bladder during the urinary retention and subsequent catheterization compared to the blood flow in the AUR group." | 7.75 | Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger. ( Kazuyama, E; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Tamamura, M, 2009) |
| "Edaravone attenuates ICH-induced brain edema, neurologic deficits, and oxidative injury." | 7.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| "In this study, we tested the hypothesis that MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one; edaravone), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats by the radical scavenging action associated with the suppression of cytotoxic myocardial injury." | 7.73 | MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats. ( Hattori, M; Kishimoto, C; Nimata, M; Okabe, TA; Shioji, K; Yuan, Z, 2005) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 7.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| " However, poor water solubility, low stability, and bioavailability in aqueous media are major EDV drawbacks." | 5.91 | Enhancing the Neuroprotection Potential of Edaravone in Transient Global Ischemia Treatment with Glutathione- (GSH-) Conjugated Poly(methacrylic acid) Nanogel as a Promising Carrier for Targeted Brain Drug Delivery. ( Bijani, S; Danafar, H; Hosseini, MJ; Islambulchilar, Z; Kalantari-Hesari, A; Mozafari, F; Ramazani, A; Rashidzadeh, H; Zare-Molaei, F, 2023) |
| "This study observed the effects of edaravone combined with Dl-3-N-butylphthalide (NBP) on the serum levels of tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), and neuron-specific enolase (NSE), and its therapeutic effect in patients with acute cerebral infarction (ACI)." | 5.51 | The effect of edaravone combined with DL-3-N-butylphthalide on the levels of tumor necrosis factor-alpha, interleukin-10, neuron-specific enolase and effect in patients with acute cerebral infarction. ( Shen, QQ; Tong, XW; Wang, W; Wu, H, 2022) |
| " Whether it can provide better outcomes when combined with edaravone injection (ERI) for the treatment of acute cerebral infarction is not well determined." | 5.41 | Edaravone combined with Shuxuening versus edaravone alone in the treatment of acute cerebral infarction: A systematic review and meta-analysis. ( Li, LD; Shi, SF; Zhou, Y, 2023) |
| "Our study aimed to investigate the effect of intravenous thrombolysis with alteplase and edaravone on cerebral hemodynamics and T lymphocyte level in patients harboring acute cerebral infarction." | 5.34 | Effects of intravenous thrombolysis with alteplase combined with edaravone on cerebral hemodynamics and T lymphocyte level in patients with acute cerebral infarction. ( Guo, SF; Li, XX; Liu, SH; Pang, SL; Zhuang, SJ, 2020) |
| "When edaravone was administered prior to ischemia and at the time of initiation of the reperfusion, liver injury was markedly reduced." | 5.33 | Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. ( Connor, HD; Fujii, H; Kono, H; Maki, A; Mason, RP; Rusyn, I; Woods, CG, 2006) |
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 5.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "The efficacy of hyperbaric oxygen (HBO) therapy combined with intravenous edaravone (free radical scavenger) administration was prospectively investigated in patients with acute embolic stroke involving the anterior cerebral circulation." | 5.12 | Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial. ( Imai, K; Izumoto, H; Kunieda, T; Mori, T; Takabatake, N; Watanabe, M, 2006) |
| "To investigate the clinical efficacy and safety of Shenxiong glucose injection combined with edaravone in the treatment of acute large-area cerebral infarction." | 4.02 | A Single-Center Clinical Study to Evaluate Shenxiong Glucose Injection Combined with Edaravone in the Treatment of Acute Large-Area Cerebral Infarction. ( Huang, P; Li, Z; Luo, J; Rong, X; Xu, X; Zeng, T, 2021) |
| "To investigate the effects of penehyclidine combined with edaravone on acute cerebral infarction (ACI) in rats." | 3.88 | Curative efficacy of penehyclidine combined with edaravone on acute cerebral infarction and their effects on serum TNF-α and NDS score in rats. ( Chen, Y; Zhao, Y, 2018) |
| " Edaravone induced a decrease in blood flow in the bladder during the urinary retention and subsequent catheterization compared to the blood flow in the AUR group." | 3.75 | Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger. ( Kazuyama, E; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Tamamura, M, 2009) |
| "Edaravone attenuates ICH-induced brain edema, neurologic deficits, and oxidative injury." | 3.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| "In this study, we tested the hypothesis that MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one; edaravone), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats by the radical scavenging action associated with the suppression of cytotoxic myocardial injury." | 3.73 | MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats. ( Hattori, M; Kishimoto, C; Nimata, M; Okabe, TA; Shioji, K; Yuan, Z, 2005) |
| "Fatty degeneration and necrosis with marked elevation of serum alanine aminotransferase and lactate dehydrogenase levels developed after CCl4 administration were significantly reduced by edaravone." | 3.72 | A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury. ( Ishii, H; Kameyama, K; Kitamura, K; Kurita, S; Nakamoto, N; Saito, H; Saito, Y; Tada, S, 2003) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 3.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| "Edaravone was infused at a dose of 30 mg, twice a day, for 14 days." | 2.71 | Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. ( , 2003) |
| " However, poor water solubility, low stability, and bioavailability in aqueous media are major EDV drawbacks." | 1.91 | Enhancing the Neuroprotection Potential of Edaravone in Transient Global Ischemia Treatment with Glutathione- (GSH-) Conjugated Poly(methacrylic acid) Nanogel as a Promising Carrier for Targeted Brain Drug Delivery. ( Bijani, S; Danafar, H; Hosseini, MJ; Islambulchilar, Z; Kalantari-Hesari, A; Mozafari, F; Ramazani, A; Rashidzadeh, H; Zare-Molaei, F, 2023) |
| "Edaravone treatment attenuated neuronal apoptosis as compared with the poisoning group (P < 0." | 1.43 | Edaravone attenuates brain damage in rats after acute CO poisoning through inhibiting apoptosis and oxidative stress. ( Bi, MJ; Bi, WK; Guo, YL; Kang, H; Li, Q; Yan, le J, 2016) |
| "He had been treated for lung cancer by chemotherapy and irradiation 3 years earlier." | 1.40 | [Case of cardiac tamponade during the treatment of acute cerebral infarction]. ( Nagasawa, H; Ono, H; Tanaka, H; Yamakawa, T, 2014) |
| "Edaravone was administered intravenously as a bolus dose of 5 mg/kg at 5 minutes, 24 hours, and 48 hours after injury (edaravone-treated rats)." | 1.33 | Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats. ( Iwashita, Y; Kuno, S; Nakamura, T; Ohta, S; Takada, H, 2005) |
| "When edaravone was administered prior to ischemia and at the time of initiation of the reperfusion, liver injury was markedly reduced." | 1.33 | Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. ( Connor, HD; Fujii, H; Kono, H; Maki, A; Mason, RP; Rusyn, I; Woods, CG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (55.56) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 5 (18.52) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, QQ | 1 |
| Wang, W | 1 |
| Wu, H | 1 |
| Tong, XW | 1 |
| Li, LD | 1 |
| Zhou, Y | 1 |
| Shi, SF | 1 |
| Mozafari, F | 1 |
| Rashidzadeh, H | 1 |
| Bijani, S | 1 |
| Zare-Molaei, F | 1 |
| Islambulchilar, Z | 1 |
| Danafar, H | 1 |
| Kalantari-Hesari, A | 1 |
| Ramazani, A | 1 |
| Hosseini, MJ | 1 |
| Li, XX | 1 |
| Liu, SH | 1 |
| Zhuang, SJ | 1 |
| Guo, SF | 1 |
| Pang, SL | 1 |
| Li, Z | 1 |
| Rong, X | 1 |
| Luo, J | 1 |
| Zeng, T | 1 |
| Huang, P | 1 |
| Xu, X | 1 |
| Chen, Y | 1 |
| Zhao, Y | 1 |
| Takahashi, S | 1 |
| Nagasawa, H | 1 |
| Ono, H | 1 |
| Tanaka, H | 1 |
| Yamakawa, T | 1 |
| Li, Q | 1 |
| Bi, MJ | 1 |
| Bi, WK | 1 |
| Kang, H | 1 |
| Yan, le J | 1 |
| Guo, YL | 1 |
| Higashi, Y | 1 |
| Shimizu, S | 1 |
| Saito, M | 1 |
| Kinoshita, Y | 1 |
| Kazuyama, E | 1 |
| Tamamura, M | 1 |
| Satoh, I | 1 |
| Satoh, K | 1 |
| Yamakawa, H | 1 |
| Yoshimura, S | 1 |
| Iwama, T | 1 |
| Isahaya, K | 1 |
| Yamada, K | 1 |
| Yamatoku, M | 1 |
| Sakurai, K | 1 |
| Takaishi, S | 1 |
| Kato, B | 1 |
| Hirayama, T | 1 |
| Hasegawa, Y | 1 |
| Xin, Y | 1 |
| Zhang, S | 1 |
| Gu, L | 1 |
| Liu, S | 1 |
| Gao, H | 1 |
| You, Z | 1 |
| Zhou, G | 1 |
| Wen, L | 1 |
| Yu, J | 1 |
| Xuan, Y | 1 |
| Wadiwala, MF | 1 |
| Sonawalla, A | 1 |
| Kamal, AK | 1 |
| Satoh, M | 1 |
| Kashihara, N | 1 |
| Fujimoto, S | 1 |
| Horike, H | 1 |
| Tokura, T | 1 |
| Namikoshi, T | 1 |
| Sasaki, T | 1 |
| Makino, H | 1 |
| Nakamoto, N | 1 |
| Tada, S | 1 |
| Kameyama, K | 1 |
| Kitamura, K | 1 |
| Kurita, S | 1 |
| Saito, Y | 1 |
| Saito, H | 1 |
| Ishii, H | 1 |
| Yamaguchi, T | 1 |
| Ida, T | 1 |
| Kobayashi, T | 1 |
| Hiraga, M | 1 |
| Oishi, K | 1 |
| Uchida, MK | 1 |
| Echizen, H | 1 |
| Ohta, S | 1 |
| Iwashita, Y | 1 |
| Takada, H | 1 |
| Kuno, S | 1 |
| Nakamura, T | 2 |
| Mishina, M | 1 |
| Komaba, Y | 1 |
| Kobayashi, S | 1 |
| Tanaka, N | 1 |
| Kominami, S | 1 |
| Fukuchi, T | 1 |
| Mizunari, T | 1 |
| Hamamoto, M | 1 |
| Teramoto, A | 1 |
| Katayama, Y | 1 |
| Nimata, M | 1 |
| Okabe, TA | 1 |
| Hattori, M | 1 |
| Yuan, Z | 1 |
| Shioji, K | 1 |
| Kishimoto, C | 1 |
| Kono, H | 1 |
| Woods, CG | 1 |
| Maki, A | 1 |
| Connor, HD | 1 |
| Mason, RP | 1 |
| Rusyn, I | 1 |
| Fujii, H | 1 |
| Tsujita, K | 1 |
| Shimomura, H | 1 |
| Kaikita, K | 1 |
| Kawano, H | 1 |
| Hokamaki, J | 1 |
| Nagayoshi, Y | 1 |
| Yamashita, T | 1 |
| Fukuda, M | 1 |
| Nakamura, Y | 1 |
| Sakamoto, T | 1 |
| Yoshimura, M | 1 |
| Ogawa, H | 1 |
| Imai, K | 1 |
| Mori, T | 1 |
| Izumoto, H | 1 |
| Takabatake, N | 1 |
| Kunieda, T | 1 |
| Watanabe, M | 1 |
| Murakami, T | 1 |
| Nakayasu, H | 1 |
| Doi, M | 1 |
| Fukada, Y | 1 |
| Hayashi, M | 1 |
| Suzuki, T | 1 |
| Takeuchi, Y | 1 |
| Nakashima, K | 1 |
| Kuroda, Y | 1 |
| Yamashita, S | 1 |
| Zhang, X | 1 |
| Miyamoto, O | 1 |
| Tamiya, T | 1 |
| Nagao, S | 1 |
| Xi, G | 1 |
| Keep, RF | 1 |
| Itano, T | 1 |
2 reviews available for edaravone and Acute Disease
| Article | Year |
|---|---|
Edaravone combined with Shuxuening versus edaravone alone in the treatment of acute cerebral infarction: A systematic review and meta-analysis.
Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Edaravone; Humans; Stroke | 2023 |
Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress.
Topics: Acute Disease; Antipyrine; Cerebral Infarction; Edaravone; Endothelium, Vascular; Free Radical Scave | 2009 |
5 trials available for edaravone and Acute Disease
| Article | Year |
|---|---|
The effect of edaravone combined with DL-3-N-butylphthalide on the levels of tumor necrosis factor-alpha, interleukin-10, neuron-specific enolase and effect in patients with acute cerebral infarction.
Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Edaravone; Humans; Interleukin-10; Phosphopyruva | 2022 |
Effects of intravenous thrombolysis with alteplase combined with edaravone on cerebral hemodynamics and T lymphocyte level in patients with acute cerebral infarction.
Topics: Acute Disease; Administration, Intravenous; Adult; Aged; Cerebral Infarction; Cerebrovascular Circul | 2020 |
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antipyrine; Cerebral Infarction; Double-Blind Method; | 2003 |
Long-term efficacy of edaravone in patients with acute myocardial infarction.
Topics: Acute Disease; Antipyrine; Arrhythmias, Cardiac; Edaravone; Free Radical Scavengers; Humans; Myocard | 2006 |
Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial.
Topics: Acute Disease; Aged; Antipyrine; Combined Modality Therapy; Edaravone; Emergency Medical Services; F | 2006 |
20 other studies available for edaravone and Acute Disease
| Article | Year |
|---|---|
Enhancing the Neuroprotection Potential of Edaravone in Transient Global Ischemia Treatment with Glutathione- (GSH-) Conjugated Poly(methacrylic acid) Nanogel as a Promising Carrier for Targeted Brain Drug Delivery.
Topics: Acute Disease; Animals; Antioxidants; Brain; Edaravone; Glutathione; Ischemia; Ischemic Stroke; Nano | 2023 |
A Single-Center Clinical Study to Evaluate Shenxiong Glucose Injection Combined with Edaravone in the Treatment of Acute Large-Area Cerebral Infarction.
Topics: Acute Disease; C-Reactive Protein; Cerebral Infarction; Drug Therapy, Combination; Drugs, Chinese He | 2021 |
Curative efficacy of penehyclidine combined with edaravone on acute cerebral infarction and their effects on serum TNF-α and NDS score in rats.
Topics: Acute Disease; Animals; Cerebral Infarction; Edaravone; HMGB1 Protein; Interleukin-6; Quinuclidines; | 2018 |
[Treatment of acute ischemic stroke: tissue clock and reperfusion].
Topics: Acute Disease; Adult; Animals; Antipyrine; Brain Infarction; Edaravone; Free Radical Scavengers; Hum | 2012 |
[Case of cardiac tamponade during the treatment of acute cerebral infarction].
Topics: Acute Disease; Adenocarcinoma; Anterior Cerebral Artery; Antipyrine; Aspirin; Cardiac Tamponade; Cer | 2014 |
Edaravone attenuates brain damage in rats after acute CO poisoning through inhibiting apoptosis and oxidative stress.
Topics: Acute Disease; Animals; Antipyrine; Apoptosis; Brain; Brain Diseases; Carbon Monoxide Poisoning; Eda | 2016 |
Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Animals; Antipyrine; Deoxyguanosine; DNA Damage; Edaravo | 2009 |
Anterior spinal artery as a collateral channel in patients with acute bilateral vertebral artery occlusions. Two case reports.
Topics: Acute Disease; Aged; Antipyrine; Arginine; Brain Stem; Cerebellum; Cerebral Revascularization; Cereb | 2009 |
Effects of edaravone, a free radical scavenger, on serum levels of inflammatory biomarkers in acute brain infarction.
Topics: Acute Disease; Aged; Aged, 80 and over; Analysis of Variance; Antipyrine; Biomarkers; Brain Infarcti | 2012 |
Electrocardiographic and biochemical evidence for the cardioprotective effect of antioxidants in acute doxorubicin-induced cardiotoxicity in the beagle dogs.
Topics: Acute Disease; Alanine Transaminase; Animals; Antibiotics, Antineoplastic; Antioxidants; Antipyrine; | 2011 |
What is the role of free radical scavengers in acute stroke?
Topics: Acute Disease; Antipyrine; Biomarkers; Brain Infarction; Edaravone; Enzyme-Linked Immunosorbent Assa | 2012 |
A novel free radical scavenger, edarabone, protects against cisplatin-induced acute renal damage in vitro and in vivo.
Topics: Acute Disease; Animals; Antipyrine; Apoptosis; Cell Size; Cell Survival; Cisplatin; Edaravone; Free | 2003 |
A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Alanine Transaminase; Aldehydes; Animals; Antipyrine; Ap | 2003 |
[Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells].
Topics: Acute Disease; Aged; Amlodipine; Animals; Antioxidants; Antipyrine; Basilar Artery; Calcium Channel | 2004 |
Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats.
Topics: Acute Disease; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hindlimb; Injections, Intrav | 2005 |
Efficacy of edaravone, a free radical scavenger, for the treatment of acute lacunar infarction.
Topics: Acute Disease; Aged; Antipyrine; Brain Infarction; Edaravone; Female; Free Radical Scavengers; Human | 2005 |
MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats.
Topics: Acute Disease; Animals; Antipyrine; Autoimmune Diseases; Cardiotonic Agents; Cytokines; Dose-Respons | 2005 |
Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage.
Topics: Acute Disease; Animals; Antipyrine; Edaravone; Electron Spin Resonance Spectroscopy; Free Radicals; | 2006 |
Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo.
Topics: Acute Disease; Antipyrine; Aspirin; Basilar Artery; Brain Infarction; Cerebellar Diseases; Cerebellu | 2006 |
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
Topics: Acute Disease; Animals; Antipyrine; Basal Ganglia; Brain Edema; Cerebral Cortex; Cerebral Hemorrhage | 2008 |