Page last updated: 2024-09-02

ecteinascidin 743 and Neutropenia

ecteinascidin 743 has been researched along with Neutropenia in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (50.00)	29.6817
2010's	8 (44.44)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Hayakawa, K; Iwata, S; Kobayashi, H; Oka, H; Tanaka, S; Ueda, T; Wakamatsu, T; Wasa, J; Yonemoto, T	1
Armento, G; Badalamenti, G; Catania, G; Incorvaia, L; Maltese, G; Napolitano, A; Santini, D; Silletta, M; Spalato Ceruso, M; Tonini, G; Valeri, S; Vincenzi, B	1
Amadio, G; Carpano, S; Ferrandina, G; Loizzi, V; Lorusso, D; Marinaccio, M; Naglieri, E; Salutari, V; Scambia, G; Tonini, G; Vincenzi, B	1
Ben Mrad, M; Collard, O; Diao, P; Espenel, S; Fournel, P; Langrand-Escure, J; Magné, N; Méry, B; Moriceau, G; Rivoirard, R; Vallard, A; Wang, G	1
Chawla, N; Chawla, SP; Gordon, EM; Sankhala, KK	1
Herzog, TJ; Teplinsky, E	1
Capri, G; Cresta, S; D'Incalci, M; De Braud, F; Feilchenfeldt, JW; Gallerani, E; Gianni, L; Ielmini, N; Jimeno, J; Locatelli, A; Noberasco, C; Perotti, A; Sessa, C; Viganò, L; Zucchetti, M	1
Capri, G; Corradino, I; Cresta, S; D'Incalci, M; De Braud, F; Gallerani, E; Gianni, L; Locatelli, A; Marsoni, S; Minoia, C; Noberasco, C; Sessa, C; Zintl, P; Zucchetti, M	1
Baconnier, M; Blay, JY; Boudou, L; Cassier, PA; Lombard-Bohas, C	1
Bidzinski, M; Ghatage, P; Gorbounova, VA; Herzog, TJ; Kaye, SB; Krasner, CN; Lebedinsky, CA; Lisyanskaya, AS; Makhson, AN; Monk, BJ; Muggia, FM; Nam, JH; Ngan, HY; Park, YC; Poveda, AM; Pujade-Lauraine, E; Rolski, J; Shen, K; Vergote, IB; Vermorken, JB	1
Blay, JY; Delaloge, S; Demetri, GD; Frontelo, P; Jiao, JJ; Le Cesne, A; Maki, RG; Misset, JL; Nieto, A; Yovine, A	1
Colombo, N; del Campo, JM; Gómez, J; Gore, M; Kaye, S; Krasner, CN; McMeekin, S; Parekh, T; Park, YC; Sessa, C; Vermorken, JB; Zintl, P	1
Butkiewicz, L; Demetri, GD; Garcia-Carbonero, R; Guzman, C; Harmon, D; Jimeno, J; Lopez-Lazaro, L; Maki, RG; Puchalski, TA; Ryan, DP; Seiden, MV; Supko, JG	1
Hing, J; Lopez-Lazaro, L; Perez-Ruixo, JJ; Soto-Matos, A; Stuyckens, K; Zannikos, P	1
Beijnen, JH; Brain, E; Cvitkovic, E; Guzman, C; Hillebrand, MJ; Jimeno, JM; López-Lázaro, L; Math t, RA; Misset, JL; Rosing, H; Schellens, JH; Taamma, A; van Kesteren, C	1
Brain, E; Cottu, P; Cvitkovic, E; Delaloge, S; Goldwasser, F; Jimeno, J; Marty, M; Misset, JL; Raymond, E; Riofrio, M; Taamma, A; Yovine, A	1
Brain, E; Cvitkovic, E; Guzman, C; Jimeno, JM; Lopez Lazaro, L; Misset, JL; Riofrio, M; Rosing, H; Taamma, A	1
Cvetkovic, RS; Figgitt, DP; Plosker, GL	1

Reviews

6 review(s) available for ecteinascidin 743 and Neutropenia

Article	Year
Trabectedin for Soft Tissue Sarcoma: Current Status and Future Perspectives. Advances in therapy, 2016, Volume: 33, Issue:7 Topics: Antineoplastic Agents, Alkylating; Dioxoles; Disease-Free Survival; Europe; Germany; Humans; Neutropenia; Randomized Controlled Trials as Topic; Sarcoma; Tetrahydroisoquinolines; Trabectedin	2016
The efficacy of trabectedin in treating ovarian cancer. Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:3 Topics: Antineoplastic Agents, Alkylating; Carcinoma, Ovarian Epithelial; Clinical Trials, Phase III as Topic; Dioxoles; Disease-Free Survival; Doxorubicin; Drug Discovery; Female; Humans; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Neutropenia; Ovarian Neoplasms; Polyethylene Glycols; Tetrahydroisoquinolines; Trabectedin; Tumor Microenvironment	2017
Trabectedin for the management of soft-tissue sarcoma. Expert review of anticancer therapy, 2009, Volume: 9, Issue:6 Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Controlled Clinical Trials as Topic; Dioxoles; DNA Repair; Female; Humans; Liver; Neutropenia; Ovarian Neoplasms; Sarcoma; Tetrahydroisoquinolines; Thrombocytopenia; Trabectedin; Transaminases	2009
Trabectedin as single agent in relapsed advanced ovarian cancer: results from a retrospective pooled analysis of three phase II trials. Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Clinical Trials, Phase II as Topic; Dioxoles; Disease-Free Survival; Drug Administration Schedule; Fatigue; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Ovarian Neoplasms; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Vomiting	2013
Mechanism-based pharmacokinetic/pharmacodynamic meta-analysis of trabectedin (ET-743, Yondelis) induced neutropenia. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:1 Topics: Antineoplastic Agents, Alkylating; Computer Simulation; Dioxoles; Drug Administration Schedule; Female; Hematopoietic Stem Cells; Humans; Infusions, Intravenous; Leukocyte Count; Leukopoiesis; Male; Models, Biological; Neutropenia; Neutrophils; Reproducibility of Results; Severity of Illness Index; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome	2008
ET-743. Drugs, 2002, Volume: 62, Issue:8 Topics: Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Dioxoles; Humans; Isoquinolines; Liver; Neoplasms; Neutropenia; Survival Analysis; Tetrahydroisoquinolines; Thrombocytopenia; Trabectedin	2002

Trials

7 trial(s) available for ecteinascidin 743 and Neutropenia

Article	Year
Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:7 Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Breast Neoplasms; Dioxoles; Doxorubicin; Drug Administration Schedule; Female; Humans; Liver; Middle Aged; Nausea; Neutropenia; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Vomiting	2009
Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dioxoles; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Neutropenia; Ovarian Neoplasms; Tetrahydroisoquinolines; Trabectedin	2009
Trabectedin plus pegylated liposomal Doxorubicin in recurrent ovarian cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jul-01, Volume: 28, Issue:19 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dioxoles; Doxorubicin; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Leukopenia; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neutropenia; Ovarian Neoplasms; Polyethylene Glycols; Stomatitis; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome	2010
A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in phase II clinical trials. Investigational new drugs, 2012, Volume: 30, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antineoplastic Agents, Alkylating; Child; Dioxoles; Female; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Rhabdomyolysis; Tetrahydroisoquinolines; Trabectedin; Young Adult	2012
Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: associations with clinical characteristics, pathophysiological variables and toxicity. Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:4 Topics: Adult; Antineoplastic Agents; Dexamethasone; Dioxoles; Humans; Infusions, Intravenous; Isoquinolines; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Neutropenia; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Transaminases	2002
Ecteinascidin-743: a marine-derived compound in advanced, pretreated sarcoma patients--preliminary evidence of activity. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Mar-01, Volume: 19, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Bone Neoplasms; Dioxoles; Disease Progression; Female; Humans; Isoquinolines; Liver; Male; Middle Aged; Neutropenia; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome	2001
Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Mar-01, Volume: 19, Issue:5 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Dioxoles; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Isoquinolines; Male; Middle Aged; Neoplasms; Neutropenia; Tetrahydroisoquinolines; Thrombocytopenia; Trabectedin	2001

Other Studies

5 other study(ies) available for ecteinascidin 743 and Neutropenia

Article	Year
Efficacy and safety of trabectedin for patients with unresectable and relapsed soft-tissue sarcoma in Japan: A Japanese Musculoskeletal Oncology Group study. Cancer, 2020, 03-15, Volume: 126, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Body Height; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Humans; Japan; Male; Middle Aged; Neutropenia; Product Surveillance, Postmarketing; Progression-Free Survival; Retrospective Studies; Rhabdomyolysis; Sarcoma; Soft Tissue Neoplasms; Trabectedin; Young Adult	2020
Body Mass Index as a Risk Factor for Toxicities in Patients with Advanced Soft-Tissue Sarcoma Treated with Trabectedin. Oncology, 2018, Volume: 95, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Dioxoles; Female; Humans; Ifosfamide; Male; Middle Aged; Neutropenia; Retrospective Studies; Risk Factors; Sarcoma; Sarcopenia; Tetrahydroisoquinolines; Thinness; Trabectedin	2018
Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study. Gynecologic oncology, 2013, Volume: 130, Issue:3 Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Asthenia; Carcinoma; Dioxoles; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neutropenia; Ovarian Neoplasms; Platinum Compounds; Retrospective Studies; Salvage Therapy; Tetrahydroisoquinolines; Trabectedin	2013
What makes real world outcomes in soft tissue sarcomas? A mono-institutional trabectedin experience. Bulletin du cancer, 2015, Volume: 102, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dioxoles; Disease Progression; Female; Humans; Male; Middle Aged; Neutropenia; Retrospective Studies; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Young Adult	2015
Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12 Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents, Alkylating; Area Under Curve; Aspartate Aminotransferases; Dioxoles; Dose-Response Relationship, Drug; Female; Humans; Isoquinolines; Liver; Male; Middle Aged; Models, Chemical; Neoplasms; Neutropenia; Tetrahydroisoquinolines; Thrombocytopenia; Time Factors; Trabectedin	2000