ecteinascidin 743 has been researched along with Lung Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Avendaño, C; de la Cuesta, E; González, JF | 1 |
| Avendaño, C; Cuesta, Ede L; González, JF; Manguan-García, C; Ortín, I; Perona, R | 1 |
| Cao, D; Gao, Z; Lin, C; Lin, Y; Liu, H; Liu, SL; Luo, L; Ma, W; Shi, Y; Wang, J; Wang, P; Wang, W; Xiang, Q; Xu, W; Zeng, Z; Zhao, Y | 1 |
| Cai, S; Ding, Z; Liu, X; Zeng, J | 1 |
| Chiba, K; Horiuchi, K; Inoue, M; Ishizaka, T; Matsuhashi, Y; Rikitake, H; Susa, M; Taguchi, E | 1 |
| Reichardt, P | 1 |
| Bongiovanni, L; Botti, L; Burocchi, A; Cancila, V; Cappetti, B; Chiodoni, C; Colombo, MP; Galvan, S; Garofalo, C; Manara, MC; Parenza, M; Ratti, C; Sangaletti, S; Scotlandi, K; Torselli, I; Tripodo, C; Valenti, CF | 1 |
| Aglietta, M; Aliberti, S; Galizia, D; Grignani, G; Nuzzo, AM; Palesandro, E; Pignochino, Y | 1 |
| Basso, U; Maruzzo, M; Montesco, MC; Rastrelli, M; Roma, A; Zanardi, E | 1 |
| Grignani, G; Martín-Broto, J; Reichardt, P; Schuler, M | 1 |
| Capri, G; Corradino, I; Cresta, S; D'Incalci, M; De Braud, F; Gallerani, E; Gianni, L; Locatelli, A; Marsoni, S; Minoia, C; Noberasco, C; Sessa, C; Zintl, P; Zucchetti, M | 1 |
| Croué, A; Pavageau, AH; Reguerre, Y; Rialland, X; Rousselet, MC | 1 |
| Contreras Ibáñez, JA; Díaz Gómez, L; Navas García, N | 1 |
| Alberola, V; Alfaro, V; Camps, C; Cobo, M; Dómine, M; Gutiérrez-Calderón, V; Isla, D; Lardelli, P; Massuti, B; Nieto, A; Provencio, M; Rosell, R; Tarón, M; Viñolas, N | 1 |
| De Pooter, CM; Faircloth, GT; Korst, AE; Lambrechts, HA; Lardon, F; Pattyn, GG; Simoens, C; Vermorken, JB | 1 |
| Beijnen, JH; Beumer, JH; Lopez-Lazaro, L; Rademaker-Lakhai, JM; Rosing, H; Schellens, JH | 1 |
| Brain, E; Jimeno, J; Misset, JL; Riofrio, M; Spielmann, M; Taamma, A; Turpin, F; Yovine, A; Zelek, L | 1 |
| Cowan, C; Koontz, MZ; Monk, BJ; Saffari, B; Tewari, D; Wallick, AC | 1 |
| Faircloth, GT; Fiebig, HH; Giavazzi, R; Hendriks, HR; Jimeno, JM; Langdon, SP | 1 |
2 review(s) available for ecteinascidin 743 and Lung Neoplasms
| Article | Year |
|---|---|
Trabectedin in Cancers: Mechanisms and Clinical Applications.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Dioxoles; Humans; Lung Neoplasms; Sarcoma; Trabectedin; Tumor Microenvironment | 2022 |
Prolonged disease stability with trabectedin in a heavily pretreated elderly patient with metastatic leiomyosarcoma of the thigh and renal failure: a case report and review of the literature.
Topics: Aged; Antineoplastic Agents, Alkylating; Dioxoles; Disease Progression; Humans; Leiomyosarcoma; Lung Neoplasms; Male; Renal Insufficiency; Salvage Therapy; Tetrahydroisoquinolines; Time Factors; Tomography, X-Ray Computed; Trabectedin; Treatment Outcome | 2013 |
4 trial(s) available for ecteinascidin 743 and Lung Neoplasms
| Article | Year |
|---|---|
Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dioxoles; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Neutropenia; Ovarian Neoplasms; Tetrahydroisoquinolines; Trabectedin | 2009 |
Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Dioxoles; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nuclear Proteins; Platinum; Tetrahydroisoquinolines; Trabectedin; Transcription Factors; Treatment Outcome | 2012 |
Trabectedin (Yondelis, formerly ET-743), a mass balance study in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Dioxoles; Feces; Female; Half-Life; Humans; Isoquinolines; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Sarcoma; Sarcoma, Synovial; Tetrahydroisoquinolines; Trabectedin | 2005 |
A phase II study of Yondelis (trabectedin, ET-743) as a 24-h continuous intravenous infusion in pretreated advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Dioxoles; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Isoquinolines; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Tetrahydroisoquinolines; Trabectedin | 2006 |
13 other study(ies) available for ecteinascidin 743 and Lung Neoplasms
| Article | Year |
|---|---|
Synthesis and cytotoxic activity of pyrazino[1,2-b]-isoquinolines, 1-(3-isoquinolyl)isoquinolines, and 6,15-iminoisoquino[3,2-b]-3-benzazocines.
Topics: Azocines; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Lung Neoplasms; Molecular Conformation; Pyrazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2007 |
Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties.
Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Cytostatic Agents; DNA Damage; G1 Phase; G2 Phase; HT29 Cells; Humans; Inhibitory Concentration 50; Isoquinolines; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Pyrazines; S Phase; Structure-Activity Relationship | 2008 |
Trabectedin induces ferroptosis via regulation of HIF-1α/IRP1/TFR1 and Keap1/Nrf2/GPX4 axis in non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Ferroptosis; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; NF-E2-Related Factor 2; Reactive Oxygen Species; Trabectedin | 2023 |
Trabectedin suppresses osteosarcoma pulmonary metastasis in a mouse tumor xenograft model.
Topics: Adolescent; Animals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Heterografts; Humans; Lung Neoplasms; Mice; Neoplasm Metastasis; Osteosarcoma; Trabectedin | 2022 |
Uncertainties that threaten the benefit/risk balance in early treatment lines for advanced or metastatic soft tissue sarcoma.
Topics: Aged, 80 and over; Chemoradiotherapy; Disease Progression; Fatal Outcome; Humans; Leiomyosarcoma; Lumbar Vertebrae; Lung; Lung Neoplasms; Male; Positron Emission Tomography Computed Tomography; Risk Assessment; Spinal Neoplasms; Trabectedin | 2021 |
Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors.
Topics: Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Cellular Reprogramming; Core Binding Factor Alpha 1 Subunit; Dioxoles; Humans; Immunotherapy; Lung Neoplasms; Osteosarcoma; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tetrahydroisoquinolines; Trabectedin; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2017 |
Response to trabectedin in a patient with advanced synovial sarcoma with lung metastases.
Topics: Adult; Antineoplastic Agents; Axilla; Combined Modality Therapy; Dioxoles; Epirubicin; Fatal Outcome; Humans; Ifosfamide; Lung Neoplasms; Male; Niacinamide; Phenylurea Compounds; Sarcoma, Synovial; Sorafenib; Tetrahydroisoquinolines; Trabectedin | 2014 |
Trabectedin clinical cases: use according to indication in diverse clinical scenarios.
Topics: Anthracyclines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Contraindications; Dacarbazine; Deoxycytidine; Dioxoles; Female; Femoral Neoplasms; Gemcitabine; Humans; Hysterectomy; Ifosfamide; Leiomyosarcoma; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Radionuclide Imaging; Remission Induction; Salvage Therapy; Sarcoma; Sarcoma, Synovial; Soft Tissue Neoplasms; Tetrahydroisoquinolines; Thigh; Tomography, X-Ray Computed; Trabectedin; Treatment Outcome; Uterine Neoplasms | 2015 |
[A rare tumour with a distinctive histological appearance].
Topics: Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arteriovenous Malformations; Bevacizumab; Biomarkers, Tumor; Combined Modality Therapy; Dactinomycin; Desmin; Diagnosis, Differential; Dioxoles; Doxorubicin; Humans; Ifosfamide; Leg; Lung Neoplasms; Male; Neoplasm Proteins; Prognosis; S100 Proteins; Sarcoma, Alveolar Soft Part; Soft Tissue Neoplasms; Staining and Labeling; Tetrahydroisoquinolines; Trabectedin; Vincristine | 2010 |
Mestastatic gastric cancer from malignant fibrous histiocytoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Dioxoles; Docetaxel; Epirubicin; Fatal Outcome; Gemcitabine; Histiocytoma, Malignant Fibrous; Humans; Ifosfamide; Lung Neoplasms; Male; Soft Tissue Neoplasms; Spinal Neoplasms; Stomach Neoplasms; Taxoids; Tetrahydroisoquinolines; Thigh; Thoracic Vertebrae; Trabectedin | 2011 |
In vitro interaction between ecteinascidin 743 (ET-743) and radiation, in relation to its cell cycle effects.
Topics: Antineoplastic Agents, Alkylating; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Dioxoles; Humans; Isoquinolines; Lung Neoplasms; Radiation-Sensitizing Agents; Tetrahydroisoquinolines; Tongue Neoplasms; Trabectedin; Urinary Bladder Neoplasms | 2003 |
Activity of trabectedin (ET-743, Yondelis) in metastatic uterine leiomyosarcoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Dioxoles; Drug Administration Schedule; Drugs, Investigational; Female; Humans; Leiomyosarcoma; Lung Neoplasms; Neoplasm Recurrence, Local; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms | 2006 |
High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer.
Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Dioxoles; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Melanoma; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Ovarian Neoplasms; Tetrahydroisoquinolines; Trabectedin | 1999 |