Page last updated: 2024-09-02

ecteinascidin 743 and Leiomyosarcoma, Epithelioid

ecteinascidin 743 has been researched along with Leiomyosarcoma, Epithelioid in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (8.70)29.6817
2010's27 (58.70)24.3611
2020's15 (32.61)2.80

Authors

AuthorsStudies
Grimison, P; King, D; Thomson, K; Zhou, DD1
Aicher, L; Black, G; Cranmer, LD; He, Q; Hermida de Viveiros, P; Johnson, R; Jones, RL; Loggers, ET; Maxwell, S; McDonnell, S; Moore, R; Pollack, SM; Smythe, KS; Wagner, MJ; Zhang, Y1
Szkandera, J1
Bakhshi, S; Pushpam, D; Sasi, A1
Chib, S; Gogia, A1
Özdemir, N; Özet, A; Sütcüoğlu, O; Yazıcı, O1
Archambaud, B; Pautier, P; Tanguy, ML1
Casali, PG; Celant, S; Comandone, A; Di Segni, S; Napolitano, A; Olimpieri, PP; Russo, P; Sanfilippo, R; Vincenzi, B1
Aubry, S; Chaigneau, L; Charon Barra, C; Hervieu, A; Isambert, N; Jary, M; Kalbacher, E; Meynard, G; Nerich, V; Neumann, F1
Aquilano, M; Becherini, C; Campanacci, DA; Francolini, G; Greto, D; Livi, L; Loi, M; Mangoni, M; Melica, ME; Salvatore, G; Salvestrini, V; Santini, C; Sottili, M; Talamonti, C; Valzano, M1
Ae, K; Fukuda, N; Hayakawa, K; Hayashi, N; Matsumoto, S; Minami, Y; Nakano, K; Ohmoto, A; Oki, R; Ono, M; Saito, M; Sato, Y; Suto, H; Takahashi, S; Tanizawa, T; Tomomatsu, J; Udagawa, S; Urasaki, T; Wang, X; Yunokawa, M1
Meeus, P; Ray-Coquard, I; Turinetto, M1
Blay, JY; de Sande González, LM; Kasper, B; Le Cesne, A; Martin-Broto, J1
Schuetze, S1
Reichardt, P1
Demetri, GD; Elias, A; Hamm, J; Hensley, ML; Jones, RL; Knoblauch, R; Maki, RG; McCarthy, S; Milhem, M; Parekh, T; Patel, S; Schuetze, SM; Van Tine, BA; von Mehren, M; Wang, G1
Garcia Del Muro, X; Ibrahim, T; Jones, RL; Le Cesne, A; Menge, F1
Merimsky, O; Shamai, S1
Kato, S; Nozaki, Y; Takagi, T; Yamaguchi, S1
Charlson, J; Chawla, SP; D'Amato, G; Demetri, GD; Forscher, C; Hensley, ML; Kaiser, P; Knoblauch, R; Livingston, M; Maki, RG; McCarthy, S; Parekh, T; Patel, S; Reed, DR; Rushing, D; Ryan, CW; Seth, R; Singh, A; von Mehren, M; Wang, G1
Casali, PG; Sanfilippo, R1
Ahrens, M; Bauer, S; Grabellus, F; Hoiczyk, M; Podleska, L; Pöttgen, C; Schuler, M; Schwindenhammer, B; Taeger, G1
Blay, JY; Casali, P; Le Cesne, A; Nieto, A; Tanović, A1
Aglietta, M; Aliberti, S; Galizia, D; Grignani, G; Nuzzo, AM; Palesandro, E; Pignochino, Y1
Elowsson, C; Krarup-Hansen, A; Mouritsen, LS; Safwat, A; Schack, LH1
Hohenberger, P; Kasper, B; Mathew, M; Pink, D; Rauch, G; Reichardt, P; Sommer, M1
Alexandre, J; Bertucci, F; Bompas, E; Chevreau, C; Collard, O; Cupissol, D; Delcambre, C; Duffaud, F; Floquet, A; Guillemet, C; Isambert, N; Lacas, B; Lavau-Denes, S; Le Cesne, A; Pautier, P; Penel, N; Piperno-Neumann, S; Selle, F; Soulié, P; Thyss, A; Toulmonde, M1
Grignani, G; Martín-Broto, J; Reichardt, P; Schuler, M1
Dean, A; Demetri, GD; Elias, A; Ganjoo, K; Hensley, ML; Jones, RL; Khokhar, NZ; Knoblauch, RE; Maki, RG; Milhem, M; Parekh, TV; Park, YC; Patel, SR; Schuetze, SM; Spira, A; Staddon, A; Tawbi, H; Van Tine, BA; von Mehren, M1
Balzarini, L; Bastoni, S; Bertuzzi, AF; Daolio, P; De Sanctis, R; Lutman, FR; Marchetti, S; Marrari, A; Mussi, C; Quagliuolo, V; Santoro, A1
Basso, U; Brunello, A; Diminutto, A; Maruzzo, M; Rastrelli, M1
Amadori, D; Bongiovanni, A; Cavaliere, D; De Vita, A; Ibrahim, T; La Manna, F; Liverani, C; Mercatali, L; Oboldi, D; Pieri, F; Ricci, M; Riva, N; Verdecchia, GM1
Gronchi, A; Saponara, M; Stacchiotti, S1
von Mehren, M; Zijoo, R1
Amunni, G; Lavacchi, D; Mazzei, T; Montelatici, S; Tavella, K; Vannini, L; Villanucci, A1
Fader, AN; Ricci, S; Stone, RL1
Blay, JY; Buckley, B; Elsayed, YA; Fanucchi, MP; Gilles, L; Le Cesne, A; Lebedinsky, C; Ray-Coquard, I; Samuels, BL; von Mehren, M1
Adenis, A; Hollebecque, A; Lebedinsky, C; Penel, N; Taieb, S1
Baker, LH; Blay, JY; Chawla, SP; Demetri, GD; Elsayed, YA; Gómez, J; Hande, KR; Izquierdo, MA; Keohan, ML; Le Cesne, A; Lebedinsky, C; Park, YC; Ritch, P; Samuels, BL; Schuetze, S; von Mehren, M1
Demetri, GD; George, S; Hartzell, TL; Morgan, J; Orgill, DP; Polson, K; Sinha, I; Theman, TA1
Bui-Nguyen, B; Italiano, A; Toulmonde, M1
Corrado, G; Ferrandina, G; Fuoco, G; Lucidi, A; Salutari, V1
Ray-Coquard, I1
Banerjee, S; Casali, PG; D'Incalci, M; Dei Tos, AP; Grosso, F; Jones, RL; Judson, I; Pilotti, S; Raspagliesi, F; Sanfilippo, R1
Blessing, JA; Burke, JJ; Hensley, ML; Monk, BJ; Muller, CY; Street, DG1
Cowan, C; Koontz, MZ; Monk, BJ; Saffari, B; Tewari, D; Wallick, AC1

Reviews

10 review(s) available for ecteinascidin 743 and Leiomyosarcoma, Epithelioid

ArticleYear
Doxorubicin combined with Trabectedin in systemic first-line M+/recurrent leiomyosarcoma patients.
    Current opinion in oncology, 2023, 07-01, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Humans; Leiomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Trabectedin

2023
Real-world evidence of the efficacy and tolerability of trabectedin in patients with advanced soft-tissue sarcoma.
    Expert review of anticancer therapy, 2020, Volume: 20, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Humans; Leiomyosarcoma; Liposarcoma; Quality of Life; Randomized Controlled Trials as Topic; Sarcoma; Trabectedin

2020
Preserving quality of life as a key treatment goal in advanced soft tissue sarcomas.
    Expert review of anticancer therapy, 2018, Volume: 18, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Female; Humans; Leiomyosarcoma; Liposarcoma, Myxoid; Male; Patient Reported Outcome Measures; Quality of Life; Sarcoma; Trabectedin; Young Adult

2018
Prolonged disease stability with trabectedin in a heavily pretreated elderly patient with metastatic leiomyosarcoma of the thigh and renal failure: a case report and review of the literature.
    Oncology research, 2013, Volume: 20, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Dioxoles; Disease Progression; Humans; Leiomyosarcoma; Lung Neoplasms; Male; Renal Insufficiency; Salvage Therapy; Tetrahydroisoquinolines; Time Factors; Tomography, X-Ray Computed; Trabectedin; Treatment Outcome

2013
The safety and efficacy of trabectedin for the treatment of liposarcoma or leiomyosarcoma.
    Expert review of anticancer therapy, 2016, Volume: 16, Issue:5

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Dioxoles; Drug Design; Humans; Leiomyosarcoma; Liposarcoma; Prognosis; Tetrahydroisoquinolines; Time Factors; Trabectedin

2016
Efficacy of trabectedin for the treatment of liposarcoma.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Dioxoles; Disease-Free Survival; Female; Humans; Leiomyosarcoma; Liposarcoma; Sarcoma; Tetrahydroisoquinolines; Trabectedin

2016
Uterine leiomyosarcoma: Epidemiology, contemporary treatment strategies and the impact of uterine morcellation.
    Gynecologic oncology, 2017, Volume: 145, Issue:1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Chemotherapy, Adjuvant; Deoxycytidine; Diagnostic Errors; Dioxoles; Docetaxel; Doxorubicin; Female; Gemcitabine; Humans; Hysterectomy; Indazoles; Laparoscopy; Leiomyoma; Leiomyosarcoma; Morcellation; Neoplasm Staging; Pyrimidines; Sulfonamides; Taxoids; Tetrahydroisoquinolines; Trabectedin; Uterine Myomectomy; Uterine Neoplasms

2017
Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-20, Volume: 27, Issue:33

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Catheterization, Central Venous; Device Removal; Dioxoles; Drainage; Extravasation of Diagnostic and Therapeutic Materials; Female; Follow-Up Studies; Humans; Immunohistochemistry; Infusions, Intravenous; Irritants; Leiomyosarcoma; Necrosis; Severity of Illness Index; Skin Ulcer; Soft Tissue Injuries; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2009
[Chemotherapy options for patients with advanced soft-tissue sarcoma beyond anthracyclines].
    Bulletin du cancer, 2010, Volume: 97, Issue:6

    Topics: Antineoplastic Agents; Dacarbazine; Deoxycytidine; Dioxoles; Docetaxel; Doxorubicin; Gemcitabine; Humans; Ifosfamide; Leiomyosarcoma; Liposarcoma; Sarcoma; Soft Tissue Neoplasms; Taxoids; Tetrahydroisoquinolines; Trabectedin

2010
An increasing role for trabectedin in gynecological cancers: efficacy in uterine sarcomas.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2011, Volume: 21 Suppl 1

    Topics: Antineoplastic Agents, Alkylating; Clinical Trials, Phase II as Topic; Dioxoles; Female; Humans; Leiomyosarcoma; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2011

Trials

10 trial(s) available for ecteinascidin 743 and Leiomyosarcoma, Epithelioid

ArticleYear
A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 06-01, Volume: 28, Issue:11

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; B7-H1 Antigen; Humans; Leiomyosarcoma; Leukocytes, Mononuclear; Liposarcoma; Trabectedin

2022
Efficacy and tolerability of trabectedin in elderly patients with sarcoma: subgroup analysis from a phase III, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 09-01, Volume: 29, Issue:9

    Topics: Administration, Intravenous; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Dacarbazine; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Progression-Free Survival; Time Factors; Trabectedin; Young Adult

2018
Overall survival and histology-specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma.
    Cancer, 2019, 08-01, Volume: 125, Issue:15

    Topics: Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Humans; Leiomyosarcoma; Liposarcoma; Male; Survival Analysis; Trabectedin

2019
Efficacy and safety of trabectedin as an early treatment for advanced or metastatic liposarcoma and leiomyosarcoma.
    Future oncology (London, England), 2014, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Dioxoles; Drug Administration Schedule; Female; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2014
Combination of trabectedin and gemcitabine for advanced soft tissue sarcomas: results of a phase I dose escalating trial of the German Interdisciplinary Sarcoma Group (GISG).
    Marine drugs, 2015, Jan-13, Volume: 13, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Deoxycytidine; Dioxoles; Drug Therapy, Combination; Female; Gemcitabine; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Sarcoma; Tetrahydroisoquinolines; Thrombocytopenia; Trabectedin; Transaminases

2015
Trabectedin in combination with doxorubicin for first-line treatment of advanced uterine or soft-tissue leiomyosarcoma (LMS-02): a non-randomised, multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dioxoles; Doxorubicin; Female; Humans; Kaplan-Meier Estimate; Leiomyosarcoma; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Soft Tissue Neoplasms; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2015
Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-10, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Dacarbazine; Dioxoles; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Survival Rate; Tetrahydroisoquinolines; Trabectedin; Young Adult

2016
Phase I combination study of trabectedin and doxorubicin in patients with soft-tissue sarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-15, Volume: 14, Issue:20

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dioxoles; Disease-Free Survival; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Leiomyosarcoma; Liposarcoma; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Sarcoma; Survival Rate; Tetrahydroisoquinolines; Trabectedin; Young Adult

2008
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Australia; Dioxoles; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Europe; Female; Humans; Ifosfamide; Infusions, Intravenous; Kaplan-Meier Estimate; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Neoplasm Staging; North America; Proportional Hazards Models; Risk Assessment; Tetrahydroisoquinolines; Time Factors; Trabectedin; Treatment Failure; Young Adult

2009
A phase II evaluation of trabectedin in the treatment of advanced, persistent, or recurrent uterine leiomyosarcoma: a gynecologic oncology group study.
    Gynecologic oncology, 2012, Volume: 124, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Dioxoles; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leiomyosarcoma; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Survival Rate; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2012

Other Studies

26 other study(ies) available for ecteinascidin 743 and Leiomyosarcoma, Epithelioid

ArticleYear
Trabectedin for metastatic liposarcoma and leiomyosarcoma: Comparison of real-world experience in an Australian sarcoma specialist center to pivotal clinical trial results.
    Asia-Pacific journal of clinical oncology, 2022, Volume: 18, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Australia; Clinical Trials as Topic; Humans; Leiomyosarcoma; Liposarcoma; Sarcoma; Soft Tissue Neoplasms; Trabectedin

2022
Keeping up the 'race pace' in a patient with nonuterine leiomyosarcoma.
    Future oncology (London, England), 2022, Volume: 18, Issue:29s

    Topics: Clinical Trials, Phase III as Topic; Doxorubicin; Humans; Leiomyosarcoma; Male; Randomized Controlled Trials as Topic; Trabectedin

2022
Doxorubicin plus trabectedin for metastatic or unresectable leiomyosarcoma.
    The Lancet. Oncology, 2022, Volume: 23, Issue:10

    Topics: Doxorubicin; Humans; Leiomyosarcoma; Trabectedin

2022
Doxorubicin plus trabectedin for metastatic or unresectable leiomyosarcoma.
    The Lancet. Oncology, 2022, Volume: 23, Issue:10

    Topics: Doxorubicin; Humans; Leiomyosarcoma; Trabectedin

2022
Doxorubicin plus trabectedin for metastatic or unresectable leiomyosarcoma.
    The Lancet. Oncology, 2022, Volume: 23, Issue:10

    Topics: Doxorubicin; Humans; Leiomyosarcoma; Trabectedin

2022
Doxorubicin plus trabectedin for metastatic or unresectable leiomyosarcoma - Authors' reply.
    The Lancet. Oncology, 2022, Volume: 23, Issue:10

    Topics: Doxorubicin; Humans; Leiomyosarcoma; Trabectedin

2022
Trabectedin use in soft-tissue sarcoma patients in a real-world setting: Data from an Italian national drug-access registry.
    International journal of cancer, 2023, 02-15, Volume: 152, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Dioxoles; Female; Humans; Leiomyosarcoma; Liposarcoma, Myxoid; Male; Registries; Sarcoma; Soft Tissue Neoplasms; Tetrahydroisoquinolines; Trabectedin

2023
Real-World Experience of Efficacy and Safety of Trabectedin in Patients with Soft Tissue Sarcoma: A Bicentric Retrospective Analysis.
    Oncology, 2022, Volume: 100, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Dioxoles; Disease-Free Survival; Humans; Leiomyosarcoma; Liposarcoma, Myxoid; Neoplasm Recurrence, Local; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms; Tetrahydroisoquinolines; Trabectedin

2022
Radiosensitizing Effect of Trabectedin on Human Soft Tissue Sarcoma Cells.
    International journal of molecular sciences, 2022, Nov-18, Volume: 23, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Fibrosarcoma; Humans; Leiomyosarcoma; Liposarcoma; Radiation-Sensitizing Agents; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Trabectedin; Tumor Microenvironment

2022
Clinical characteristics of sarcoma cases in which long-term disease control was achieved with trabectedin treatment: A retrospective study.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Adult; Humans; Leiomyosarcoma; Liposarcoma, Myxoid; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms; Trabectedin

2023
Trabectedin: useful in leiomyosarcoma and liposarcoma, but less so in other soft tissue sarcomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2021, Volume: 32, Issue:8

    Topics: Humans; Leiomyosarcoma; Liposarcoma; Sarcoma; Trabectedin

2021
Uncertainties that threaten the benefit/risk balance in early treatment lines for advanced or metastatic soft tissue sarcoma.
    Future oncology (London, England), 2021, Volume: 17, Issue:21s

    Topics: Aged, 80 and over; Chemoradiotherapy; Disease Progression; Fatal Outcome; Humans; Leiomyosarcoma; Lumbar Vertebrae; Lung; Lung Neoplasms; Male; Positron Emission Tomography Computed Tomography; Risk Assessment; Spinal Neoplasms; Trabectedin

2021
Trabectedin for Advanced Soft Tissue Sarcoma: Ten Year Real-Life Perspective.
    The Israel Medical Association journal : IMAJ, 2018, Volume: 20, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Cohort Studies; Disease-Free Survival; Female; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Retrospective Studies; Sarcoma; Survival Rate; Trabectedin; Young Adult

2018
[An Effective Treatment of Relapsed Leiomyosarcoma with Fourth-Line Trabectedin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Dioxoles; Female; Humans; Leiomyosarcoma; Middle Aged; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2019
The intriguing patterns of tumor response to trabectedin.
    Expert review of anticancer therapy, 2013, Volume: 13, Issue:6 Suppl 1

    Topics: Antineoplastic Agents, Alkylating; Dioxoles; Female; Humans; Leiomyosarcoma; Liposarcoma, Myxoid; Molecular Targeted Therapy; Sarcoma; Tetrahydroisoquinolines; Time Factors; Trabectedin; Treatment Outcome; Tumor Microenvironment; Uterine Neoplasms

2013
Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age.
    International journal of oncology, 2013, Volume: 43, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Dioxoles; Disease Progression; Disease-Free Survival; Female; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Sarcoma; Tetrahydroisoquinolines; Trabectedin

2013
The Danish experience with trabectedin treatment for metastatic sarcoma: Importance of hyponatremia.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chondrosarcoma; Denmark; Dioxoles; Female; Humans; Hyponatremia; Karnofsky Performance Status; Leiomyosarcoma; Liposarcoma; Middle Aged; Multivariate Analysis; Retrospective Studies; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Young Adult

2015
Trabectedin clinical cases: use according to indication in diverse clinical scenarios.
    Future oncology (London, England), 2015, Volume: 11, Issue:11 Suppl

    Topics: Anthracyclines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Contraindications; Dacarbazine; Deoxycytidine; Dioxoles; Female; Femoral Neoplasms; Gemcitabine; Humans; Hysterectomy; Ifosfamide; Leiomyosarcoma; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Radionuclide Imaging; Remission Induction; Salvage Therapy; Sarcoma; Sarcoma, Synovial; Soft Tissue Neoplasms; Tetrahydroisoquinolines; Thigh; Tomography, X-Ray Computed; Trabectedin; Treatment Outcome; Uterine Neoplasms

2015
Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dioxoles; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leiomyosarcoma; Liposarcoma; Male; Middle Aged; Neoplasm Metastasis; Retrospective Studies; Sarcoma; Survival Rate; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Young Adult

2015
Long-term response to first-line trabectedin in an elderly female patient with a metastatic leiomyosarcoma unfit for anthracycline.
    Anti-cancer drugs, 2016, Volume: 27, Issue:3

    Topics: Aged; Antineoplastic Agents; Dioxoles; Fatal Outcome; Female; Humans; Leiomyosarcoma; Rectal Neoplasms; Tetrahydroisoquinolines; Time Factors; Trabectedin

2016
Long-lasting activity of trabectedin in refractory uterine leiomyosarcoma: a case report.
    BMC cancer, 2015, Dec-22, Volume: 15

    Topics: Antineoplastic Agents, Alkylating; Dioxoles; Female; Humans; Leiomyosarcoma; Middle Aged; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Uterine Neoplasms

2015
Stable disease in a patient with metastatic leiomyosarcoma treated with trabectedin.
    Anti-cancer drugs, 2017, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Dioxoles; Female; Humans; Leiomyosarcoma; Neoplasm Metastasis; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2017
Inadequacy of size-based response criteria to assess the efficacy of trabectedin among metastatic sarcoma patients.
    Investigational new drugs, 2010, Volume: 28, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Clinical Trials, Phase II as Topic; Dioxoles; Humans; Leiomyosarcoma; Male; Middle Aged; Neoplasm Metastasis; Peritoneal Neoplasms; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2010
Prolonged clinical response to trabectedin in a heavily pretreated patient with advanced uterine leiomyosarcoma: a case report and literature review.
    Gynecologic oncology, 2011, May-01, Volume: 121, Issue:2

    Topics: Dioxoles; Female; Humans; Leiomyosarcoma; Middle Aged; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2011
Trabectedin in advanced uterine leiomyosarcomas: a retrospective case series analysis from two reference centers.
    Gynecologic oncology, 2011, Volume: 123, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dioxoles; Disease-Free Survival; Female; Humans; Leiomyosarcoma; Middle Aged; Retrospective Studies; Survival Rate; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2011
Activity of trabectedin (ET-743, Yondelis) in metastatic uterine leiomyosarcoma.
    Gynecologic oncology, 2006, Volume: 102, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Dioxoles; Drug Administration Schedule; Drugs, Investigational; Female; Humans; Leiomyosarcoma; Lung Neoplasms; Neoplasm Recurrence, Local; Tetrahydroisoquinolines; Trabectedin; Uterine Neoplasms

2006