Compounds > ecteinascidin 743
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ecteinascidin 743 and Colonic Neoplasms

ecteinascidin 743 has been researched along with Colonic Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avendaño, C; de la Cuesta, E; González, JF1
Antony, S; Kohn, EC; Munson, PJ; Nishizuka, S; Pommier, Y; Reimers, M; Stevens, EV; Varma, S; Weinstein, JN; Young, L1
Bassano, L; Bergamaschi, D; D'Incalci, M; Damia, G; Erba, E; Faircloth, GT; Ronzoni, S1
Goldwasser, F; Kohlhagen, G; Pommier, Y; Takebayashi, Y; Urasaki, Y1
Friedman, D; Gorfajn, B; Hu, Z; Kolb, EA; Scotto, KW1

Other Studies

5 other study(ies) available for ecteinascidin 743 and Colonic Neoplasms

ArticleYear
Synthesis and cytotoxic activity of pyrazino[1,2-b]-isoquinolines, 1-(3-isoquinolyl)isoquinolines, and 6,15-iminoisoquino[3,2-b]-3-benzazocines.
    Bioorganic & medicinal chemistry, 2007, Jan-01, Volume: 15, Issue:1

    Topics: Azocines; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Lung Neoplasms; Molecular Conformation; Pyrazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2007
Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; Dioxoles; DNA Repair; Female; Gene Expression Profiling; Humans; Ovarian Neoplasms; Protein Array Analysis; Tetrahydroisoquinolines; Trabectedin

2008
Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclins; Dioxoles; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Dioxoles; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; Formazans; Humans; Immunoenzyme Techniques; Isoquinolines; Proliferating Cell Nuclear Antigen; Tetrahydroisoquinolines; Tetrazolium Salts; Trabectedin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Ecteinascidin-743 inhibits activated but not constitutive transcription.
    Cancer research, 2002, Jun-15, Volume: 62, Issue:12

    Topics: Antineoplastic Agents, Alkylating; CCAAT-Binding Factor; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dioxoles; Genes, MDR; Humans; Isoquinolines; Promoter Regions, Genetic; Sp1 Transcription Factor; Tetrahydroisoquinolines; Trabectedin; Transcriptional Activation; Tumor Cells, Cultured

2002