ecteinascidin 743 has been researched along with Breast Cancer in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 11 (61.11) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, W; Deng, W; Hao, Q; Huang, Z; Li, J; Li, Q; Liu, D; Liu, Z; Su, R; Vadgama, J; Wang, K; Wang, P; Wu, K; Wu, Y | 1 |
| Aissaoui, D; Essafi-Benkhadir, K; Souid, S; Srairi-Abid, N | 1 |
| Alfaro, V; Blum, JL; Byrski, T; Campone, M; Cullell-Young, M; Delaloge, S; Ghouadni, A; Gonçalves, A; Kahatt, C; Lardelli, P; Lubinski, J; Nieto, A | 1 |
| Anand, A; Giri, GV; Govind Babu, K; Jacob, LA; Koppaka, D; Kumar, RV; Lakshmaiah, KC; Lokanatha, D; Lokesh, KN; Rajeev, LK; Rudresha, AH; Saldanha, SC; Suresh Babu, MC | 1 |
| Atmaca, H; Bozkurt, E; Karaca, B; Uslu, R; Uzunoglu, S | 1 |
| Blum, JL; Byrski, T; Campone, M; Cullell-Young, M; Delaloge, S; Gonçalves, A; Kahatt, C; Lardelli, P; Lubinski, J; Nieto, A; Wolp-Diniz, R | 1 |
| Atmaca, H; Uzunoglu, S | 1 |
| Bayever, E; Del Prete, SA; Goldstein, LJ; Gurtler, J; Michiels, B; Semiglazov, VF; Tjulandin, S | 1 |
| D'Incalci, M; Zambelli, A | 1 |
| Aftimos, P; Awada, A; Cortés, J; Delaloge, S; Espie, M; Extremera, S; Fernández-García, EM; Lardelli, P; López-Tarruella, S; Martín, M; Oliveira, M | 1 |
| Aracil, M; D'Incalci, M; Italiano, A; Kaye, SB; Lorusso, D; Monk, BJ; Tanović, A | 1 |
| Kim, HJ; Kim, JW; Kim, M; Lee, KH; Suh, DH | 1 |
| Capri, G; Cresta, S; D'Incalci, M; De Braud, F; Feilchenfeldt, JW; Gallerani, E; Gianni, L; Ielmini, N; Jimeno, J; Locatelli, A; Noberasco, C; Perotti, A; Sessa, C; Viganò, L; Zucchetti, M | 1 |
| Baconnier, M; Blay, JY; Boudou, L; Cassier, PA; Lombard-Bohas, C | 1 |
| Aracil, M; Benítez, J; Domingo, S; Fernández, V; García, MJ; Muñoz-Repeto, I; Nieto, A; Palacios, J; Robles, MJ; Saucedo-Cuevas, LP; Tercero, JC | 1 |
| Banerjee, D; Bertino, JR; Brennan, MF; Chou, TC; Guan, Y; Li, W; Scotto, KW; Takahashi, N; Wada-Takahashi, Y | 1 |
| Brain, E; Jimeno, J; Misset, JL; Riofrio, M; Spielmann, M; Taamma, A; Turpin, F; Yovine, A; Zelek, L | 1 |
| Dean-Colomb, W; Esteva, FJ | 1 |
6 review(s) available for ecteinascidin 743 and Breast Cancer
| Article | Year |
|---|---|
Trabectedin (Yondelis®) as a Therapeutic Option in Gynecological Cancers: A Focus on its Mechanisms of Action, Clinical Activity and Genomic Predictors of Drug Response.
Topics: Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Female; Genital Neoplasms, Female; Genomics; Humans; Trabectedin | 2020 |
Trabectedin for the treatment of breast cancer.
Topics: Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; Dioxoles; DNA Repair; Female; Humans; Neoplasm Metastasis; Tetrahydroisoquinolines; Trabectedin; Tumor Microenvironment | 2016 |
Trabectedin as a chemotherapy option for patients with BRCA deficiency.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Dioxoles; Doxorubicin; Female; Genes, BRCA1; Genes, BRCA2; Hereditary Breast and Ovarian Cancer Syndrome; Humans; Ovarian Neoplasms; Polyethylene Glycols; Sarcoma; Tetrahydroisoquinolines; Trabectedin | 2016 |
Major clinical research advances in gynecologic cancer in 2015.
Topics: Biomedical Research; Breast Neoplasms; Combined Modality Therapy; Dioxoles; Endometrial Neoplasms; Female; Genital Neoplasms, Female; Humans; Immunotherapy; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Ovarian Neoplasms; Papillomavirus Vaccines; Precision Medicine; Tetrahydroisoquinolines; Trabectedin; Uterine Cervical Neoplasms; Uterine Neoplasms | 2016 |
Trabectedin for the management of soft-tissue sarcoma.
Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Controlled Clinical Trials as Topic; Dioxoles; DNA Repair; Female; Humans; Liver; Neutropenia; Ovarian Neoplasms; Sarcoma; Tetrahydroisoquinolines; Thrombocytopenia; Trabectedin; Transaminases | 2009 |
Emerging agents in the treatment of anthracycline- and taxane-refractory metastatic breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Clinical Trials as Topic; Deoxycytidine; Dioxoles; Diphtheria Toxin; Drug Resistance, Neoplasm; Drugs, Investigational; Epothilones; Female; Furans; Gemcitabine; Glutamates; Guanine; Humans; Interleukin-2; Ketones; Lapatinib; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Quinazolines; Recombinant Fusion Proteins; Tetrahydroisoquinolines; Trabectedin; Vinblastine; Vinorelbine | 2008 |
6 trial(s) available for ecteinascidin 743 and Breast Cancer
| Article | Year |
|---|---|
Higher antitumor activity of trabectedin in germline BRCA2 carriers with advanced breast cancer as compared to BRCA1 carriers: A subset analysis of a dedicated phase II trial.
Topics: Adult; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Ductal, Breast; Dioxoles; Female; Genes, BRCA1; Genes, BRCA2; Germ-Line Mutation; Heterozygote; Humans; Middle Aged; Response Evaluation Criteria in Solid Tumors; Tetrahydroisoquinolines; Trabectedin | 2017 |
Activity of trabectedin in germline BRCA1/2-mutated metastatic breast cancer: results of an international first-in-class phase II study.
Topics: Adult; Antineoplastic Agents, Alkylating; Breast Neoplasms; Dioxoles; Disease-Free Survival; Female; Genes, BRCA1; Genes, BRCA2; Germ-Line Mutation; Humans; Kaplan-Meier Estimate; Middle Aged; Tetrahydroisoquinolines; Trabectedin | 2014 |
Trabectedin as a single-agent treatment of advanced breast cancer after anthracycline and taxane treatment: a multicenter, randomized, phase II study comparing 2 administration regimens.
Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Dioxoles; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate; Taxoids; Tetrahydroisoquinolines; Trabectedin; Young Adult | 2014 |
Phase 2 Study of Trabectedin in Patients With Hormone Receptor-Positive, HER-2-Negative, Advanced Breast Carcinoma According to Expression of Xeroderma Pigmentosum G Gene.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Breast Neoplasms; Dioxoles; Disease-Free Survival; DNA-Binding Proteins; Drug Administration Schedule; Endonucleases; Female; Humans; Infusions, Intravenous; Middle Aged; Nuclear Proteins; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tetrahydroisoquinolines; Trabectedin; Transcription Factors; Treatment Outcome | 2016 |
Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer.
Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Breast Neoplasms; Dioxoles; Doxorubicin; Drug Administration Schedule; Female; Humans; Liver; Middle Aged; Nausea; Neutropenia; Sarcoma; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome; Vomiting | 2009 |
A phase II study of Yondelis (trabectedin, ET-743) as a 24-h continuous intravenous infusion in pretreated advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Dioxoles; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Isoquinolines; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Tetrahydroisoquinolines; Trabectedin | 2006 |
6 other study(ies) available for ecteinascidin 743 and Breast Cancer
| Article | Year |
|---|---|
A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes-Associated Breast Cancer.
Topics: Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucose; Glycolysis; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Mice; Monocarboxylic Acid Transporters; Muscle Proteins; Prognosis; Trabectedin | 2022 |
Primary breast angiosarcoma - a single institution experience from a tertiary cancer center in South India.
Topics: Adult; Breast; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Dioxoles; Female; Hemangiosarcoma; Humans; India; Middle Aged; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Taxoids; Tertiary Care Centers; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome | 2018 |
A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-Associated Death Protein; Breast Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumor; Cytochromes c; Dioxoles; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mitochondria; Mitochondrial Proteins; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Tetrahydroisoquinolines; Trabectedin | 2013 |
Anti-angiogenic effects of trabectedin (Yondelis; ET-743) on human breast cancer cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Dioxoles; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Human Umbilical Vein Endothelial Cells; Humans; Insulin-Like Growth Factor Binding Protein 2; MCF-7 Cells; Neovascularization, Pathologic; Plasminogen Activator Inhibitor 1; RNA, Messenger; Tetrahydroisoquinolines; Tissue Inhibitor of Metalloproteinase-1; Trabectedin; Vascular Endothelial Growth Factor A | 2014 |
Analysis of DNA repair-related genes in breast cancer reveals CUL4A ubiquitin ligase as a novel biomarker of trabectedin response.
Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cullin Proteins; Dioxoles; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Profiling; Gene Knockdown Techniques; Gene Silencing; Humans; Inhibitory Concentration 50; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome | 2013 |
Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Camptothecin; Cisplatin; Dioxoles; Doxorubicin; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Inhibitory Concentration 50; Isoquinolines; Mice; Mice, Nude; Mitosis; Paclitaxel; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |