Page last updated: 2024-09-02

ecopipam and Cocaine Abuse

ecopipam has been researched along with Cocaine Abuse in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chausmer, AL; Griffiths, RR; Kelly, RY; Smith, BJ1
Davidson, C; Ellinwood, EH; Gao, WY; Lee, TH1
Clarke, L; Coffin, V; Cornish, J; Glue, P; Kampman, K; Kaplan, HL; O'Brien, CP; Poole, S; Romach, MK; Sellers, EM; Somer, GR1
Kosten, TA; Kosten, TR; McCance-Katz, EF1
Fischman, MW; Foltin, RW; Haney, M; Ward, AS1
Bigelow, GE; Donny, EC; Nann-Vernotica, E; Walsh, SL1

Trials

4 trial(s) available for ecopipam and Cocaine Abuse

ArticleYear
Cocaine-like subjective effects of nicotine are not blocked by the D1 selective antagonist ecopipam (SCH 39166).
    Behavioural pharmacology, 2003, Volume: 14, Issue:2

    Topics: Adult; Benzazepines; Blood Pressure; Cocaine-Related Disorders; Dopamine Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; GABA Modulators; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Nicotine; Pain Measurement; Receptors, Dopamine D1; Time Factors; Triazolam

2003
Attenuation of the euphoric effects of cocaine by the dopamine D1/D5 antagonist ecopipam (SCH 39166)
    Archives of general psychiatry, 1999, Volume: 56, Issue:12

    Topics: Adult; Behavior, Addictive; Benzazepines; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Euphoria; Female; Humans; Male; Receptors, Dopamine; Reward

1999
Effects of ecopipam, a selective dopamine D1 antagonist, on smoked cocaine self-administration by humans.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Administration, Inhalation; Adult; Benzazepines; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Hemodynamics; Humans; Male; Psychiatric Status Rating Scales; Receptors, Dopamine D1; Self Administration

2001
Repeated administration of the D1/5 antagonist ecopipam fails to attenuate the subjective effects of cocaine.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Adult; Benzazepines; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Receptors, Dopamine D1; Receptors, Dopamine D5; Smoking; Smoking Cessation; Surveys and Questionnaires

2001

Other Studies

2 other study(ies) available for ecopipam and Cocaine Abuse

ArticleYear
Altered activity of midbrain dopamine neurons following 7-day withdrawal from chronic cocaine abuse is normalized by D2 receptor stimulation during the early withdrawal phase.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1

    Topics: Animals; Apomorphine; Benzazepines; Cocaine-Related Disorders; Dopamine; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Male; Mesencephalon; Neurons; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Substantia Nigra; Ventral Tegmental Area

1999
Going from the bedside back to the bench with ecopipam: a new strategy for cocaine pharmacotherapy development.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Benzazepines; Cocaine-Related Disorders; Dopamine Antagonists; Humans; Research Design

2001