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econazole and Candidiasis, Genital

econazole has been researched along with Candidiasis, Genital in 52 studies

Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"An open, multi-centre study was carried out in 117 pregnant women presenting with vaginal candidosis to assess the effectiveness of econazole in providing mycological control and symptom relief, and in preventing, as far as possible, the risk of contamination of the newborn: nearly 50% of the patients were in the last month of pregnancy."9.05Efficacy of econazole ('Gyno-Pevaryl' 150) in vaginal candidosis during pregnancy. ( Beek, JM; Declercq, JA; Goormans, E; Loendersloot, EW; Roelofs, HJ; van Zanten, A, 1985)
"An open, multi-centre study was carried out in 117 pregnant women presenting with vaginal candidosis to assess the effectiveness of econazole in providing mycological control and symptom relief, and in preventing, as far as possible, the risk of contamination of the newborn: nearly 50% of the patients were in the last month of pregnancy."5.05Efficacy of econazole ('Gyno-Pevaryl' 150) in vaginal candidosis during pregnancy. ( Beek, JM; Declercq, JA; Goormans, E; Loendersloot, EW; Roelofs, HJ; van Zanten, A, 1985)
"Econazole was less acceptable to patients than clotrimazole."2.67Econazole and clotrimazole in the treatment of vaginal candidiasis: a double blind comparative study. ( Perera, J; Seneviratne, HR, 1994)
"Econazole nitrate (Ecostatin; Squib) in two dosage schedules, 150 mg per day for 3 days and 50 mg per day for 14 days, was found to be extremely effective, with cure rates of 84,9% and 92,4% respectively."2.65Econazole nitrate in the treatment of candidal vaginitis. ( Bloch, B; Kretzel, A, 1980)
"The high rate of recurrence of this condition is noted and the need for at least 6 months' follow-up in future trials of candidacides is emphasized."2.65Vulvovaginal candidiasis: treatment and recurrence. ( Dennerstein, GJ; Langley, R, 1982)
"Econazole1 is a recently introduced imidazole antifungal agent which is very closely related structurally to another imidazole derivative, miconazole."2.36Econazole: a review of its antifungal activity and therapeutic efficacy. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1978)
"01) improved the solubility and in vitro bioavailability of the low solubility drug and the mucoadhesive strength."1.35Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate. ( Albertini, B; Brigidi, P; Di Sabatino, M; Passerini, N; Rodriguez, L; Vitali, B, 2009)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199038 (73.08)18.7374
1990's9 (17.31)18.2507
2000's4 (7.69)29.6817
2010's1 (1.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furneri, PM1
Corsello, S1
Masellis, G1
Salvatori, M1
Cammarata, E1
Roccasalva, LS1
Mangiafico, A1
Tempera, G1
Albertini, B1
Passerini, N1
Di Sabatino, M1
Vitali, B1
Brigidi, P1
Rodriguez, L1
Sosto, F1
Benvenuti, C1
Mårdh, PA1
Wågström, J1
Landgren, M1
Holmén, J1
Bloch, B1
Kretzel, A1
Kippax, RA1
Caradoc-Davies, G1
Meech, RJ1
Gabriel, G1
Thin, RN2
Marcano, C1
Feo, M1
Krohn, K1
Vinnerberg, A1
Gouveia, DC1
Jones da Silva, C1
Valent, M1
Klobusický, M1
Valentová, M1
Rana, C1
Appleton, B1
Williams, R1
Stettendorf, S2
Benijts, G2
Vignali, M1
Kreysing, W2
Cohen, J1
Dennerstein, GJ1
Langley, R1
Karoussos, K3
Carvalho, A1
Coelho, P1
Gomes, V1
Graça, L1
Carvalho, J1
Autunes, AB1
Andrade, C1
Filipe, G1
Pereira, MH1
Trossarelli, GF1
Curti, A1
Bocci, A1
Obolensky, W1
Simon, U1
Kobilková, J1
Vojtĕchovská, M1
Krobová, I1
Hamrová, D1
Bingham, JS1
Steele, CE1
Selvaggi, L2
Restaino, A2
Loizzi, P2
Causio, F1
Mollica, G1
Brown, D1
Binder, GL1
Gardner, HL1
Wells, J1
Rubin, A1
Russell, JM1
Mauff, A1
Vignalli, M1
Rubio, B1
Gonzalez, R1
Perera, J1
Seneviratne, HR1
Damianov, L1
Dukovski, A1
White, DJ1
Johnson, EM1
Warnock, DW1
Południewski, G1
Bielecki, M1
Kluz-Kowal, AB1
Sjöberg, I1
Nylander Lundqvist, EN1
Ghelardi, E1
Tavanti, A1
Lupetti, A1
Celandroni, F1
Boldrini, E1
Campa, M1
Senesi, S1
Cros, C1
Chevallier, T1
Dellenbach, P1
Thomas, JL1
Guerin, V1
Ochsenbein, E1
Contet-Audonneau, N1
Heel, RC1
Brogden, RN1
Speight, TM1
Avery, GS1
Schuerwegh, W2
Balmer, JA2
Lecart, C1
Claerhout, F1
Franck, R1
Godts, P1
Lilien, C1
Macours, L1
Longrée, H1
Mine, M1
Strebelle, P1
Rhemrev, PE1
Lestienne, MC1
Knüsel, H1
Lurie, D1
Bardiaux, M1
Bonhomme, J1
Crimail, P1
Darmon, M1
Guillaumin, JP1
Julien-Laferrière, P1
Lièvre, HL1
Le Louet, JM1
Leroy, B1
Martin-Dupray, D1
Torre, MP1
Osser, S1
Haglund, A1
Weström, L1
Van Cutsem, J1
Robinson, AJ1
Wilson, JD1
Spencer, RS1
Kinghorn, GR1
Pavić, N1
Gschwind, C1
Krause, U1
Chaisilwattana, P1
Roongpisuthipong, A1
Bhiraleus, P1
Chaiprasert, A1
Corosu, R1
Urbanetti, S1
Goormans, E1
Beek, JM1
Declercq, JA1
Loendersloot, EW1
Roelofs, HJ1
van Zanten, A1
Cohen, L1
Bradbeer, CS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hormonal Contraceptive Use and the Risk of Provoked Vestibulodynia- A Prospective Study[NCT01741948]0 participants (Actual)Observational2012-01-31Withdrawn (stopped due to the study has never started. my grant request was denied.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for econazole and Candidiasis, Genital

ArticleYear
Econazole: a review of its antifungal activity and therapeutic efficacy.
    Drugs, 1978, Volume: 16, Issue:3

    Topics: Adult; Animals; Bacterial Infections; Candidiasis, Vulvovaginal; Child; Dogs; Drug Resistance, Micro

1978

Trials

22 trials available for econazole and Candidiasis, Genital

ArticleYear
Econazole-polycarbophil, a new delivery system for topical therapy: microbiological and clinical results on vaginal candidiasis.
    Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:3

    Topics: Acrylic Resins; Adolescent; Adult; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; D

2008
Controlled study on thymol + eugenol vaginal douche versus econazole in vaginal candidiasis and metronidazole in bacterial vaginosis.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:2

    Topics: Administration, Intravaginal; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Chemistry, Pharma

2011
Econazole nitrate in the treatment of candidal vaginitis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Aug-23, Volume: 58, Issue:8

    Topics: Adult; Candida albicans; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Pregnancy

1980
Clotrimazole and econazole in the treatment of vaginal candidosis. A single-blind comparison.
    The British journal of venereal diseases, 1983, Volume: 59, Issue:1

    Topics: Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Econazole; Female; Humans; Imidaz

1983
Open comparison of the efficacy, toleration and safety of tioconazole and econazole in the 3-day treatment of vaginal candidiasis.
    Gynakologische Rundschau, 1983, Volume: 23 Suppl 1

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Double-Bl

1983
Oxiconazole in the treatment of vaginal candidiasis: single dose versus 3-day treatment with econazole.
    Pharmatherapeutica, 1984, Volume: 3, Issue:10

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Drug Administration Schedule; Econazole; Female

1984
Three-day therapy of vaginal candidiasis with clotrimazole vaginal tablets and econazole ovules: a multicenter comparative study.
    Chemotherapy, 1982, Volume: 28 Suppl 1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Econazole; Fem

1982
Vulvovaginal candidiasis: treatment and recurrence.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1982, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Child; Clotrimazole; Econazole; Fem

1982
Gyno-Pevaryl 150: a new drug for the treatment of vaginal candidosis.
    The Journal of international medical research, 1981, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Econazole; Female; Humans; I

1981
[Vulvovaginal mycoses. Clinical study of a new antimycotic drug econazole].
    Minerva ginecologica, 1981, Volume: 33, Issue:5

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Contraceptives, Oral;

1981
Comparison of econazole and clotrimazole in the treatment of vulvovaginal candidiasis.
    Obstetrics and gynecology, 1980, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Humans; Imidazoles; M

1980
Efficacy of econazole in the treatment of candidiasis and other vaginal discharges.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Mar-15, Volume: 57, Issue:11

    Topics: Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Econazole; Female; Humans; Imidazoles;

1980
Three-day therapy of vaginal candidiasis with clotrimazole vaginal tablets and econazole ovules: a multicentre comparative study.
    Current medical research and opinion, 1980, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Humans; Imidazo

1980
Econazole and clotrimazole in the treatment of vaginal candidiasis: a double blind comparative study.
    The Ceylon medical journal, 1994, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Clotrimazole; Double-Blind Method; Econazole; Fe

1994
[Prophylaxis of puerperal infections using the Gyno-Pevaryl 150 preparation].
    Ginekologia polska, 1995, Volume: 66, Issue:2

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Pregnancy; Puerperal Infect

1995
Topical treatment of vaginal candidosis with sertaconazole and econazole sustained-release suppositories.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2000, Volume: 71 Suppl 1

    Topics: Administration, Intravaginal; Adolescent; Adult; Aged; Antifungal Agents; Candidiasis, Vulvovaginal;

2000
A new treatment of vaginal candidiasis: three-day treatment with econazole.
    European journal of obstetrics, gynecology, and reproductive biology, 1979, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Eco

1979
Treatment of candidal vaginitis. A prospective randomized investigator-blind multicenter study comparing topically applied econazole with oral fluconazole.
    Acta obstetricia et gynecologica Scandinavica, 1991, Volume: 70, Issue:1

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Candidiasis, Vulvovaginal; Econazole; Fem

1991
[One-day trial therapy with 500 mg clotrimazole vaginal tablets and 150 mg econazole nitrate-depot ovules in vaginal mycoses: results of an open comparative study].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1988, Apr-12, Volume: 77, Issue:15

    Topics: Administration, Intravaginal; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Delayed-Action Prepara

1988
Efficacy of econazole ('Gyno-Pevaryl' 150) in vaginal candidosis during pregnancy.
    Current medical research and opinion, 1985, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Econazole; Female; Humans; I

1985
Is more than one application of an antifungal necessary in the treatment of acute vaginal candidiasis?
    American journal of obstetrics and gynecology, 1985, Aug-01, Volume: 152, Issue:7 Pt 2

    Topics: Amphotericin B; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole

1985
Comparison of econazole and isoconazole as single dose treatment for vaginal candidosis.
    Genitourinary medicine, 1985, Volume: 61, Issue:6

    Topics: Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Econazole; Female; Humans; Imidazoles; M

1985

Other Studies

29 other studies available for econazole and Candidiasis, Genital

ArticleYear
Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Mar-02, Volume: 36, Issue:4-5

    Topics: Adhesives; Antifungal Agents; Biological Availability; Candida albicans; Candidiasis, Vulvovaginal;

2009
Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: I. Analyses of a unique database.
    Infectious diseases in obstetrics and gynecology, 2004, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Databases as Topic; D

2004
Polymicrobial nature of vaginitis in young women: a microbiological and therapeutic study.
    The New Zealand medical journal, 1982, Mar-24, Volume: 95, Issue:704

    Topics: Adolescent; Adult; Anaerobiosis; Bacteria; Candidiasis, Vulvovaginal; Econazole; Female; Gardnerella

1982
[Effectiveness of econazole on pregnant women with vulvo-vaginal candidiasis].
    Mycopathologia, 1983, Feb-17, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Anal Canal; Candida albicans; Candidiasis, Vulvovaginal; Drug Evaluation; Econazo

1983
[Changes in vaginal biocenosis after administration of the preparation econazol nitrate].
    Bratislavske lekarske listy, 1983, Volume: 80, Issue:2

    Topics: Adult; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Trichomonas Vaginitis; Vagi

1983
Three day treatment of vaginitis with econazole nitrate cream.
    Australian family physician, 1984, Volume: 13, Issue:4

    Topics: Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Econazole; Female; Humans; Imidazoles; Vaginal Cr

1984
Open comparison of the efficacy, toleration and safety of tioconazole cream and econazole ovules used in the 3-day treatment of patients with vaginal candidiasis.
    Gynakologische Rundschau, 1983, Volume: 23 Suppl 1

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazol

1983
[Diagnosis and therapy of vulvovaginal mycosis (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1981, Volume: 38, Issue:10

    Topics: Adult; Antifungal Agents; Bacteriological Techniques; Candidiasis, Vulvovaginal; Econazole; Female;

1981
[Econazole in the treatment of mycotic colpitis (author's transl)].
    Sbornik lekarsky, 1982, Volume: 84, Issue:4

    Topics: Adolescent; Adult; Candida; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Mycose

1982
Treatment of vaginal candidosis with econazole nitrate and nystatin. A comparative study.
    The British journal of venereal diseases, 1981, Volume: 57, Issue:3

    Topics: Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Nystatin; Patient Compliance

1981
[Study of the bacterial flora associated with vaginitis caused by Candida albicans].
    Minerva ginecologica, 1981, Volume: 33, Issue:9

    Topics: Bacteria; Candida; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Vagina; Vaginit

1981
[Econazole in the treatment of vaginitis caused by Candida albicans].
    Minerva ginecologica, 1981, Volume: 33, Issue:12

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Middle Aged

1981
Vulvo-vaginal candidosis and its treatment with the new fungicidal substance econazole.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Suppositories

1980
[Modern antimycotic therapy in obstetrics].
    Akusherstvo i ginekologiia, 1993, Volume: 32, Issue:3

    Topics: Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Econazole; Female; Humans; Pregnancy; Pregnancy C

1993
Management of persistent vulvo vaginal candidosis due to azole-resistant Candida glabrata.
    Genitourinary medicine, 1993, Volume: 69, Issue:2

    Topics: Administration, Oral; Administration, Topical; Adult; Antifungal Agents; Candidiasis, Vulvovaginal;

1993
Vulvar vestibulitis in the north of Sweden. An epidemiologic case-control study.
    The Journal of reproductive medicine, 1997, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Case-Control Studies; Contraceptive

1997
Control of Candida albicans murine vaginitis by topical administration of polycarbophil-econazole complex.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9

    Topics: Acrylic Resins; Administration, Topical; Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Econ

1998
[In vitro determination of the texture of 3 gynecologic antifungal agents: TX 15338 (Monazole, sertaconazole nitrate) and 2 related products].
    Presse medicale (Paris, France : 1983), 1998, Dec-05, Volume: 27, Issue:38

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Thiophenes

1998
Clinical evaluation of econazole nitrate in 1% vaginal cream for treatment of vaginal candidosis.
    European journal of obstetrics, gynecology, and reproductive biology, 1978, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Middle Aged; Va

1978
Three-day treatment of vulvovaginal Candida mycoses.
    Mykosen. Supplement, 1978, Volume: 1

    Topics: Administration, Intravaginal; Candidiasis, Vulvovaginal; Drug Administration Schedule; Econazole; Fe

1978
Three methods of application of econazole in the treatment of vaginal candidiasis.
    The Journal of international medical research, 1979, Volume: 7, Issue:5

    Topics: Administration, Topical; Adult; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Mi

1979
[Vulvovaginal mycoses-stort-term treatment with Econazole (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1977, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Middle Ag

1977
[Three-day treatment on vaginal candidiasis (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1977, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Middle Aged; Su

1977
Three-day therapy of vulvovaginal candidiasis with econazole: a multicentric study comprising 996 cases.
    American journal of obstetrics and gynecology, 1976, Oct-15, Volume: 126, Issue:4

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Chemical Phenomena; Chemistry; Drug Administrati

1976
[Progress in treatment of vulvo-vaginal mycoses: econazole].
    Semaine des hopitaux. Therapeutique, 1976, Volume: 52, Issue:9

    Topics: Administration, Topical; Candidiasis, Vulvovaginal; Drug Evaluation; Econazole; Female; Humans; Imid

1976
The in vitro activity of terconazole against yeasts: its topical long-acting therapeutic efficacy in experimental vaginal candidiasis in rats.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:4 Pt 2

    Topics: Administration, Topical; Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis, Vulvovagi

1991
Econazole nitrate (150 mg) single dose vaginal pessary compared with clotrimazole (10%) single dose vaginal cream to treat women with vaginal candidiasis.
    Genitourinary medicine, 1989, Volume: 65, Issue:3

    Topics: Candidiasis, Vulvovaginal; Clotrimazole; Drug Evaluation; Econazole; Female; Humans; Imidazoles; Pes

1989
Three-day therapy of vulvovaginal candidosis with econazole.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1987, Volume: 70, Issue:9

    Topics: Administration, Intravaginal; Adolescent; Adult; Candidiasis, Vulvovaginal; Drug Administration Sche

1987
[Therapy of vaginal mycoses in pregnancy with econazole depot].
    Minerva ginecologica, 1986, Volume: 38, Issue:6

    Topics: Administration, Topical; Candidiasis, Vulvovaginal; Delayed-Action Preparations; Econazole; Female;

1986