econazole has been researched along with Cancer of Prostate in 4 studies
Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The econazole-induced increase in [Ca2+]i was reduced by 48% by removal of extracellular Ca2+, suggesting that the econazole-induced increase in [Ca2+]i was composed of extracellular Ca2+ influx and intracellular Ca2+." | 1.33 | Effects of econazole on Ca2+ levels in and the growth of human prostate cancer PC3 cells. ( Chang, CH; Chang, HT; Chen, WC; Chou, CT; Hsieh, CH; Hsu, SS; Huang, JK; Jan, CR; Liu, CS; Liu, SI, 2005) |
| "In human prostate cancer, a correlation between the mRNA expression of the Ca(2+) channel TRPV6 and the staging of the cancer has been described." | 1.33 | TRPV6 potentiates calcium-dependent cell proliferation. ( Flockerzi, V; Hoth, M; Niemeyer, BA; Philipp, SE; Schwarz, EC; Strauss, B; Wissenbach, U, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clement, OO | 1 |
| Freeman, CM | 1 |
| Hartmann, RW | 1 |
| Handratta, VD | 1 |
| Vasaitis, TS | 1 |
| Brodie, AM | 1 |
| Njar, VC | 1 |
| Landowski, CP | 1 |
| Bolanz, KA | 1 |
| Suzuki, Y | 1 |
| Hediger, MA | 1 |
| Huang, JK | 1 |
| Liu, CS | 1 |
| Chou, CT | 1 |
| Liu, SI | 1 |
| Hsu, SS | 1 |
| Chang, HT | 1 |
| Hsieh, CH | 1 |
| Chang, CH | 1 |
| Chen, WC | 1 |
| Jan, CR | 1 |
| Schwarz, EC | 1 |
| Wissenbach, U | 1 |
| Niemeyer, BA | 1 |
| Strauss, B | 1 |
| Philipp, SE | 1 |
| Flockerzi, V | 1 |
| Hoth, M | 1 |
4 other studies available for econazole and Cancer of Prostate
| Article | Year |
|---|---|
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
Topics: Algorithms; Antineoplastic Agents; Azoles; Binding Sites; Enzyme Inhibitors; Humans; Hydrogen Bondin | 2003 |
Chemical inhibitors of the calcium entry channel TRPV6.
Topics: Animals; Breast Neoplasms; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Proliferation; | 2011 |
Effects of econazole on Ca2+ levels in and the growth of human prostate cancer PC3 cells.
Topics: Antineoplastic Agents; Calcium Channels, L-Type; Calcium Signaling; Cell Line, Tumor; Cell Prolifera | 2005 |
TRPV6 potentiates calcium-dependent cell proliferation.
Topics: Anilides; Calcium Channels; Calcium Signaling; Cell Line; Cell Proliferation; Cell Survival; Econazo | 2006 |