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econazole and Aneuploid

econazole has been researched along with Aneuploid in 16 studies

Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"The synopsis of the in vivo test results in the first collaborative CEC Aneuploidy Project with 10 selected chemicals, colchicine (COL), econazole (EZ), chloral hydrate (CH), hydroquinone (HQ), diazepam (DZ), thiabendazole (TB), cadmium chloride (CD), thimerosal (TM), pyrimethamine (PY) and vinblastine (VBL), allowed several conclusions."4.78Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. ( Adler, ID, 1993)
", colchicine (COL), econazole(EZ) and hydroquinone (HQ) have been assayed by means of C-Mitotic (CM) effects, micronucleus (MN) and chromosomal aberration (CA) test for their effects of aneuploid induction in mouse bone marrow cells COL induced poly/aneuploid in mouse bone marrow cells."3.68[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells]. ( Adler, ID; Kliesch, U; Miller, B; Wang, X, 1991)
"Pyrimethamine did not inhibit the assembly of microtubules, but produced aberrant forms."1.29Effects of potential aneuploidy inducing agents on microtubule assembly in vitro. ( Hartley-Asp, B; Wallin, M, 1993)
"The test chemicals included in the EC Aneuploidy Project were evaluated for their ability to induce aneuploidy or aneuploidy related endpoints in assays using in vitro tubulin polymerisation, fungi and wheat."1.29An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens. ( Parry, JM, 1993)
"Cadmium chloride was negative in the chromosome enumeration assay and hydroquinone yielded inconclusive results."1.29A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens. ( Parry, EM; Parry, JM; Warr, TJ, 1993)
"Mitomycin-C (MMC) was used as a positive control for the induction of micronuclei."1.29The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. ( Lynch, AM; Parry, JM, 1993)
"An analysis of chromosomal aberrations was carried out in bone marrow cells of mice with the first five chemicals: colchicine (COL), econazole (EZ), chloralhydrate (CH), hydroquinone (HQ) and diazepam (DIAZ)."1.28Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells. ( Adler, ID; Xu, W, 1990)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's15 (93.75)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferguson, LR1
Morcombe, P1
Triggs, CN1
Natarajan, AT2
Leopardi, P1
Zijno, A1
Bassani, B1
Pacchierotti, F1
Adler, ID3
Wallin, M1
Hartley-Asp, B1
Parry, JM4
Warr, TJ1
Parry, EM1
Sors, A1
Duivenvoorden, WC1
Meijers, M1
Zwanenburg, TS1
Lynch, AM1
Gibson, DP1
Aardema, MJ1
Kerckaert, GA1
Carr, GJ1
Brauninger, RM1
LeBoeuf, RA1
Antoccia, A1
Degrassi, F1
Battistoni, A1
Ciliutti, P1
Tanzarella, C1
Wang, X1
Miller, B1
Kliesch, U1
Crebelli, R1
Conti, G1
Conti, L1
Carere, A1
Xu, W1
Kappas, A1

Reviews

2 reviews available for econazole and Aneuploid

ArticleYear
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromos

1993
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Aspergillus; Cadmium; Cadmium Chloride; Cell Cycle; Cells, Cultured; Chloral Hy

1993

Other Studies

14 other studies available for econazole and Aneuploid

ArticleYear
The size of cytokinesis-blocked micronuclei in human peripheral blood lymphocytes as a measure of aneuploidy induction by Set A compounds in the EEC trial.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Cell Division; Cells, Cultured; Chloral Hydrate; Colchicine; Cytoplasm; Diazepam; Dose-R

1993
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral H

1993
In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Bone Marrow; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine;

1993
Effects of potential aneuploidy inducing agents on microtubule assembly in vitro.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Brain; Cadmium; Cadmium Chloride; Cattle; Chloral Hydrate; Chlorides; Colchicin

1993
An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Co

1993
A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat

1993
Induction of mitotic aneuploidy using Chinese hamster primary embryonic cells. Test results of 10 chemicals.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Colchic

1993
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat

1993
Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay.
    Mutation research, 1995, Volume: 343, Issue:1

    Topics: Aneuploidy; Animals; Asbestos; Benomyl; Cadmium; Cadmium Chloride; Carcinogenicity Tests; Carcinogen

1995
In vitro micronucleus test with kinetochore staining: evaluation of test performance.
    Mutagenesis, 1991, Volume: 6, Issue:4

    Topics: Aneuploidy; Antibodies, Monoclonal; Cadmium; Cadmium Chloride; Cell Line; Chloral Hydrate; Chromosom

1991
[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells].
    Yi chuan xue bao = Acta genetica Sinica, 1991, Volume: 18, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Chromosome Aberrations; Colchicine; Econazole; Female; Hydroquinon

1991
In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans.
    Mutagenesis, 1991, Volume: 6, Issue:2

    Topics: Aneuploidy; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chromosomes, Fungal; C

1991
Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells.
    Mutagenesis, 1990, Volume: 5, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Chloral Hydrate; Chromosome Aberrations; Colchi

1990
On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations.
    Progress in clinical and biological research, 1989, Volume: 318

    Topics: Aneuploidy; Animals; Aspergillus nidulans; Benomyl; Chloral Hydrate; Colchicine; Econazole; Hydroqui

1989