econazole has been researched along with Aneuploid in 16 studies
Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The synopsis of the in vivo test results in the first collaborative CEC Aneuploidy Project with 10 selected chemicals, colchicine (COL), econazole (EZ), chloral hydrate (CH), hydroquinone (HQ), diazepam (DZ), thiabendazole (TB), cadmium chloride (CD), thimerosal (TM), pyrimethamine (PY) and vinblastine (VBL), allowed several conclusions." | 4.78 | Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. ( Adler, ID, 1993) |
| ", colchicine (COL), econazole(EZ) and hydroquinone (HQ) have been assayed by means of C-Mitotic (CM) effects, micronucleus (MN) and chromosomal aberration (CA) test for their effects of aneuploid induction in mouse bone marrow cells COL induced poly/aneuploid in mouse bone marrow cells." | 3.68 | [A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells]. ( Adler, ID; Kliesch, U; Miller, B; Wang, X, 1991) |
| "Pyrimethamine did not inhibit the assembly of microtubules, but produced aberrant forms." | 1.29 | Effects of potential aneuploidy inducing agents on microtubule assembly in vitro. ( Hartley-Asp, B; Wallin, M, 1993) |
| "The test chemicals included in the EC Aneuploidy Project were evaluated for their ability to induce aneuploidy or aneuploidy related endpoints in assays using in vitro tubulin polymerisation, fungi and wheat." | 1.29 | An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens. ( Parry, JM, 1993) |
| "Cadmium chloride was negative in the chromosome enumeration assay and hydroquinone yielded inconclusive results." | 1.29 | A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens. ( Parry, EM; Parry, JM; Warr, TJ, 1993) |
| "Mitomycin-C (MMC) was used as a positive control for the induction of micronuclei." | 1.29 | The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. ( Lynch, AM; Parry, JM, 1993) |
| "An analysis of chromosomal aberrations was carried out in bone marrow cells of mice with the first five chemicals: colchicine (COL), econazole (EZ), chloralhydrate (CH), hydroquinone (HQ) and diazepam (DIAZ)." | 1.28 | Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells. ( Adler, ID; Xu, W, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 15 (93.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferguson, LR | 1 |
| Morcombe, P | 1 |
| Triggs, CN | 1 |
| Natarajan, AT | 2 |
| Leopardi, P | 1 |
| Zijno, A | 1 |
| Bassani, B | 1 |
| Pacchierotti, F | 1 |
| Adler, ID | 3 |
| Wallin, M | 1 |
| Hartley-Asp, B | 1 |
| Parry, JM | 4 |
| Warr, TJ | 1 |
| Parry, EM | 1 |
| Sors, A | 1 |
| Duivenvoorden, WC | 1 |
| Meijers, M | 1 |
| Zwanenburg, TS | 1 |
| Lynch, AM | 1 |
| Gibson, DP | 1 |
| Aardema, MJ | 1 |
| Kerckaert, GA | 1 |
| Carr, GJ | 1 |
| Brauninger, RM | 1 |
| LeBoeuf, RA | 1 |
| Antoccia, A | 1 |
| Degrassi, F | 1 |
| Battistoni, A | 1 |
| Ciliutti, P | 1 |
| Tanzarella, C | 1 |
| Wang, X | 1 |
| Miller, B | 1 |
| Kliesch, U | 1 |
| Crebelli, R | 1 |
| Conti, G | 1 |
| Conti, L | 1 |
| Carere, A | 1 |
| Xu, W | 1 |
| Kappas, A | 1 |
2 reviews available for econazole and Aneuploid
| Article | Year |
|---|---|
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromos | 1993 |
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
Topics: Aneuploidy; Animals; Aspergillus; Cadmium; Cadmium Chloride; Cell Cycle; Cells, Cultured; Chloral Hy | 1993 |
14 other studies available for econazole and Aneuploid
| Article | Year |
|---|---|
The size of cytokinesis-blocked micronuclei in human peripheral blood lymphocytes as a measure of aneuploidy induction by Set A compounds in the EEC trial.
Topics: Aneuploidy; Cell Division; Cells, Cultured; Chloral Hydrate; Colchicine; Cytoplasm; Diazepam; Dose-R | 1993 |
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral H | 1993 |
In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells.
Topics: Aneuploidy; Animals; Bone Marrow; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine; | 1993 |
Effects of potential aneuploidy inducing agents on microtubule assembly in vitro.
Topics: Aneuploidy; Animals; Brain; Cadmium; Cadmium Chloride; Cattle; Chloral Hydrate; Chlorides; Colchicin | 1993 |
An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens.
Topics: Aneuploidy; Animals; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Co | 1993 |
A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat | 1993 |
Induction of mitotic aneuploidy using Chinese hamster primary embryonic cells. Test results of 10 chemicals.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Colchic | 1993 |
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat | 1993 |
Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay.
Topics: Aneuploidy; Animals; Asbestos; Benomyl; Cadmium; Cadmium Chloride; Carcinogenicity Tests; Carcinogen | 1995 |
In vitro micronucleus test with kinetochore staining: evaluation of test performance.
Topics: Aneuploidy; Antibodies, Monoclonal; Cadmium; Cadmium Chloride; Cell Line; Chloral Hydrate; Chromosom | 1991 |
[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells].
Topics: Aneuploidy; Animals; Bone Marrow; Chromosome Aberrations; Colchicine; Econazole; Female; Hydroquinon | 1991 |
In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans.
Topics: Aneuploidy; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chromosomes, Fungal; C | 1991 |
Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells.
Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Chloral Hydrate; Chromosome Aberrations; Colchi | 1990 |
On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations.
Topics: Aneuploidy; Animals; Aspergillus nidulans; Benomyl; Chloral Hydrate; Colchicine; Econazole; Hydroqui | 1989 |