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econazole and Abnormalities, Autosome

econazole has been researched along with Abnormalities, Autosome in 7 studies

Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"The synopsis of the in vivo test results in the first collaborative CEC Aneuploidy Project with 10 selected chemicals, colchicine (COL), econazole (EZ), chloral hydrate (CH), hydroquinone (HQ), diazepam (DZ), thiabendazole (TB), cadmium chloride (CD), thimerosal (TM), pyrimethamine (PY) and vinblastine (VBL), allowed several conclusions."4.78Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. ( Adler, ID, 1993)
", colchicine (COL), econazole(EZ) and hydroquinone (HQ) have been assayed by means of C-Mitotic (CM) effects, micronucleus (MN) and chromosomal aberration (CA) test for their effects of aneuploid induction in mouse bone marrow cells COL induced poly/aneuploid in mouse bone marrow cells."3.68[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells]. ( Adler, ID; Kliesch, U; Miller, B; Wang, X, 1991)
"Dose-related numerical chromosomal aberrations are induced by colchicine and vinblastine, the only chemicals that also induce c-mitotic effects in a wide range of doses."1.29C-mitosis and numerical chromosome aberration analyses in human lymphocytes: 10 known or suspected spindle poisons. ( Di Sibio, A; Lomi, A; Sbrana, I; Scarcelli, V, 1993)
"An analysis of chromosomal aberrations was carried out in bone marrow cells of mice with the first five chemicals: colchicine (COL), econazole (EZ), chloralhydrate (CH), hydroquinone (HQ) and diazepam (DIAZ)."1.28Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells. ( Adler, ID; Xu, W, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Natarajan, AT1
Adler, ID3
Sbrana, I1
Di Sibio, A1
Lomi, A1
Scarcelli, V1
Marrazzini, A1
Betti, C1
Bernacchi, F1
Barrai, I1
Barale, R1
Antoccia, A1
Degrassi, F1
Battistoni, A1
Ciliutti, P1
Tanzarella, C1
Wang, X1
Miller, B1
Kliesch, U1
Xu, W1

Reviews

1 review available for econazole and Abnormalities, Autosome

ArticleYear
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromos

1993

Other Studies

6 other studies available for econazole and Abnormalities, Autosome

ArticleYear
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral H

1993
C-mitosis and numerical chromosome aberration analyses in human lymphocytes: 10 known or suspected spindle poisons.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromosome Aberrations; Colc

1993
Micronucleus test and metaphase analyses in mice exposed to known and suspected spindle poisons.
    Mutagenesis, 1994, Volume: 9, Issue:6

    Topics: Animals; Bone Marrow Cells; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides;

1994
In vitro micronucleus test with kinetochore staining: evaluation of test performance.
    Mutagenesis, 1991, Volume: 6, Issue:4

    Topics: Aneuploidy; Antibodies, Monoclonal; Cadmium; Cadmium Chloride; Cell Line; Chloral Hydrate; Chromosom

1991
[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells].
    Yi chuan xue bao = Acta genetica Sinica, 1991, Volume: 18, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Chromosome Aberrations; Colchicine; Econazole; Female; Hydroquinon

1991
Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells.
    Mutagenesis, 1990, Volume: 5, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Chloral Hydrate; Chromosome Aberrations; Colchi

1990