ebselen has been researched along with Zika Virus Infection in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Zika Virus Infection: A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen (SPI-1005) is an active selenoorganic compound that can be found potential inhibitory activity against different types of viral infections such as zika virus, influenza A virus, HCV, and HIV-1; and also be found to exhibit promising antiviral activity against SARS-CoV-2 in cell-based assays but its particular target action against specific non-structural and structural proteins of SARS-CoV-2 is unclear to date." | 1.72 | Ebselen suitably interacts with the potential SARS-CoV-2 targets: an ( Abdalla, M; Ali, N; Khalipha, ABR; Mondal, M; Sarkar, C, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Sarkar, C | 1 |
| Abdalla, M | 1 |
| Mondal, M | 1 |
| Khalipha, ABR | 1 |
| Ali, N | 1 |
| Simanjuntak, Y | 1 |
| Liang, JJ | 1 |
| Chen, SY | 1 |
| Li, JK | 1 |
| Lee, YL | 1 |
| Wu, HC | 1 |
| Lin, YL | 1 |
3 other studies available for ebselen and Zika Virus Infection
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Ebselen suitably interacts with the potential SARS-CoV-2 targets: an
Topics: Antiviral Agents; Azoles; COVID-19; COVID-19 Drug Treatment; Humans; Molecular Docking Simulation; M | 2022 |
Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azoles; Cell Nucleus Shape; Cell Nuc | 2018 |