ebselen has been researched along with Vasospasm, Intracranial in 2 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of ebselen relative to nimodipine in an animal model of subarachnoid hemorrhage." | 7.76 | Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats. ( Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M; Ugurbas, E, 2010) |
| " The monkeys were randomly divided into three groups according to Ebselen dosage: 1) no dosage or non-treated group; 2) high-dose Ebselen group; and 3) low-dose Ebselen group." | 5.31 | Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. ( Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Takeuchi, H; Tsuchida, A, 2000) |
| "We investigated the effect of ebselen relative to nimodipine in an animal model of subarachnoid hemorrhage." | 3.76 | Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats. ( Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M; Ugurbas, E, 2010) |
| " The monkeys were randomly divided into three groups according to Ebselen dosage: 1) no dosage or non-treated group; 2) high-dose Ebselen group; and 3) low-dose Ebselen group." | 1.31 | Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. ( Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Takeuchi, H; Tsuchida, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gul, S | 1 |
| Bahadir, B | 1 |
| Hanci, V | 1 |
| Acikgoz, S | 1 |
| Bektas, S | 1 |
| Ugurbas, E | 1 |
| Ankarali, H | 1 |
| Kalayci, M | 1 |
| Acikgoz, B | 1 |
| Handa, Y | 1 |
| Kaneko, M | 1 |
| Takeuchi, H | 1 |
| Tsuchida, A | 1 |
| Kobayashi, H | 1 |
| Kubota, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Aneurysms: a Retrospective Study on the Experience in Our Hospital With a Comparative Analysis Between the Different Techniques Used in Its Treatment[NCT04792944] | 247 participants (Actual) | Observational | 2007-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for ebselen and Vasospasm, Intracranial
| Article | Year |
|---|---|
Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Azoles; Brain; Drug Administration Schedule; Female; In | 2010 |
Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates.
Topics: Animals; Antioxidants; Azoles; Cerebral Angiography; Chronic Disease; Dose-Response Relationship, Dr | 2000 |