ebselen has been researched along with Retinal Degeneration in 1 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that ebselen via its ability to reduce reactive oxygen species (ROS) and augment nuclear factor-like 2 (Nrf2) anti-oxidants would attenuate hypoxia-induced damage to macroglial Müller cells and also lessen retinal vasculopathy." | 7.81 | Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina. ( de Haan, JB; Deliyanti, D; Figgett, WA; Talia, DM; Tan, SM; Wilkinson-Berka, JL, 2015) |
| " We hypothesized that ebselen via its ability to reduce reactive oxygen species (ROS) and augment nuclear factor-like 2 (Nrf2) anti-oxidants would attenuate hypoxia-induced damage to macroglial Müller cells and also lessen retinal vasculopathy." | 3.81 | Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina. ( de Haan, JB; Deliyanti, D; Figgett, WA; Talia, DM; Tan, SM; Wilkinson-Berka, JL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, SM | 1 |
| Deliyanti, D | 1 |
| Figgett, WA | 1 |
| Talia, DM | 1 |
| de Haan, JB | 1 |
| Wilkinson-Berka, JL | 1 |
1 other study available for ebselen and Retinal Degeneration
| Article | Year |
|---|---|
Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina.
Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Biomarkers; Blotting, Western; Cells, Cultured; Dis | 2015 |