Page last updated: 2024-10-26

ebselen and Pneumonia

ebselen has been researched along with Pneumonia in 5 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"People with chronic obstructive pulmonary disease (COPD) are susceptible to respiratory infections which exacerbate pulmonary and/or cardiovascular complications, increasing their likelihood of death."1.72Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice. ( Almerdasi, SA; Bozinovski, S; Brassington, K; Chan, SMH; De Luca, SN; Dobric, A; Mou, K; Oseghale, O; Selemidis, S; Seow, HJ; Vlahos, R, 2022)
"Oxidative stress is increased in COPD, IAV-induced lung inflammation and AECOPD."1.43Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice. ( Bozinovski, S; Gunasinghe, P; Oostwoud, LC; Selemidis, S; Seow, HJ; Vlahos, R; Ye, JM, 2016)
"Treatment with ebselen (10 mg/kg) significantly decreased pulmonary inflammation as indicated by the albumin concentration and the number of neutrophils in the bronchoalveolar lavage fluid 18 h after the ozone exposure."1.31Ebselen decreases ozone-induced pulmonary inflammation in rats. ( Hashimoto, K; Hirano, K; Ishii, Y; Masuyama, K; Mochizuki, M; Morishima, Y; Nomura, A; Sagai, M; Sakamoto, T; Sekizawa, K; Uchida, Y, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Brassington, K1
Chan, SMH1
De Luca, SN1
Dobric, A1
Almerdasi, SA1
Mou, K1
Seow, HJ4
Oseghale, O1
Bozinovski, S4
Selemidis, S3
Vlahos, R4
Oostwoud, LC1
Gunasinghe, P1
Ye, JM1
Duong, C1
Crack, PJ2
Anderson, GP2
Yatmaz, S1
Gualano, RC1
Wong, ZX1
Stambas, J1
Ishii, Y1
Hashimoto, K1
Hirano, K1
Morishima, Y1
Mochizuki, M1
Masuyama, K1
Nomura, A1
Sakamoto, T1
Uchida, Y1
Sagai, M1
Sekizawa, K1

Other Studies

5 other studies available for ebselen and Pneumonia

ArticleYear
Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice.
    Clinical science (London, England : 1979), 2022, 04-29, Volume: 136, Issue:8

    Topics: Animals; Azoles; Cigarette Smoking; Humans; Influenza A virus; Influenza, Human; Isoindoles; Lung; M

2022
Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice.
    Scientific reports, 2016, Feb-15, Volume: 6

    Topics: Acetophenones; Animals; Azoles; Disease Models, Animal; Humans; Influenza A virus; Isoindoles; Male;

2016
Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:3

    Topics: Animals; Antioxidants; Azoles; Bronchoalveolar Lavage Fluid; Cell Count; Chemotactic Factors; Gene E

2010
Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:1

    Topics: Adaptive Immunity; Animals; Azoles; Bronchoalveolar Lavage Fluid; CD8-Positive T-Lymphocytes; Chemok

2013
Ebselen decreases ozone-induced pulmonary inflammation in rats.
    Lung, 2000, Volume: 178, Issue:4

    Topics: Acute Disease; Albumins; Analysis of Variance; Animals; Antioxidants; Azoles; Blotting, Northern; Br

2000