ebselen has been researched along with Parkinsonian Disorders in 2 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen is an antioxidant drug with glutathione peroxidase-like activity and a proven neuroprotective action in stroke patients." | 1.31 | The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease. ( Blanchard, V; Daniel, N; Imperato, A; Moussaoui, S; Obinu, MC; Reibaud, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhanasekaran, M | 1 |
| Uthayathas, S | 1 |
| Karuppagounder, SS | 1 |
| Parameshwaran, K | 1 |
| Suppiramaniam, V | 1 |
| Ebadi, M | 1 |
| Brown-Borg, HM | 1 |
| Moussaoui, S | 1 |
| Obinu, MC | 1 |
| Daniel, N | 1 |
| Reibaud, M | 1 |
| Blanchard, V | 1 |
| Imperato, A | 1 |
2 other studies available for ebselen and Parkinsonian Disorders
| Article | Year |
|---|---|
Ebselen effects on MPTP-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Azoles; Brain; Cell Line, Tumor | 2006 |
The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Azoles; Behavior, Animal; Blood Proteins; Callit | 2000 |