Page last updated: 2024-10-26

ebselen and Neoplasms

ebselen has been researched along with Neoplasms in 8 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Yan, J1
Guo, Y1
Wang, Y1
Mao, F1
Huang, L1
Li, X1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
JastrzÄ…b, A1
Skrzydlewska, E1
Hou, W1
Lu, S1
Zhao, H1
Yu, Y1
Xu, H1
Yu, B1
Su, L1
Lin, C1
Ruan, BH1
Thomas, AG1
Rojas, C1
Tanega, C1
Shen, M1
Simeonov, A1
Boxer, MB1
Auld, DS1
Ferraris, DV1
Tsukamoto, T1
Slusher, BS1
Jing, F1
Fu, X1
Li, S1
Li, B1
Zhao, J1
Wang, X1
Liu, Y1
Chen, B1
Nosengo, N1

Reviews

2 reviews available for ebselen and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Thioredoxin-dependent system. Application of inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2021, Volume: 36, Issue:1

    Topics: Antineoplastic Agents; Benzene Derivatives; Enzyme Inhibitors; Gene Expression Regulation, Neoplasti

2021

Other Studies

6 other studies available for ebselen and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents.
    European journal of medicinal chemistry, 2015, May-05, Volume: 95

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Drug Design; Flow Cytometry; Human

2015
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP
    Biochemical and biophysical research communications, 2019, 01-29, Volume: 509, Issue:1

    Topics: Antineoplastic Agents; Azoles; Binding Sites; Cell Line, Tumor; Cell Proliferation; Escherichia coli

2019
Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors.
    Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2

    Topics: AIDS Dementia Complex; Apomorphine; Azoles; Benzophenanthridines; Cell Proliferation; Dose-Response

2013
Synthesis and in vitro antiproliferative evaluation of novel hybrids from 1,3,4-thiadiazole and benzisoselenazolone.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:6

    Topics: Antineoplastic Agents; Azoles; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proli

2015
Can you teach old drugs new tricks?
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Azoles; Bipolar Disorder; Carbazoles; Clinical Trials, Phase II as Topic; Dipyridamole; Dru

2016