ebselen has been researched along with Myocardial Ischemia in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the infarct-limiting effect of a selenoorganic compound, ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one], in a canine coronary artery occlusion-reperfusion model of myocardial infarction." | 7.69 | Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction. ( Hori, M; Hoshida, S; Kamada, T; Kuzuya, T; Nishida, M; Tada, M; Yamashita, N, 1994) |
| "We investigated the infarct-limiting effect of a selenoorganic compound, ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one], in a canine coronary artery occlusion-reperfusion model of myocardial infarction." | 3.69 | Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction. ( Hori, M; Hoshida, S; Kamada, T; Kuzuya, T; Nishida, M; Tada, M; Yamashita, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cabigas, EB | 1 |
| Ding, G | 1 |
| Chen, T | 1 |
| Saafir, TB | 1 |
| Pendergrass, KD | 1 |
| Wagner, MB | 1 |
| Davis, ME | 1 |
| Hoshida, S | 1 |
| Kuzuya, T | 1 |
| Nishida, M | 1 |
| Yamashita, N | 1 |
| Hori, M | 1 |
| Kamada, T | 1 |
| Tada, M | 1 |
| Maulik, N | 1 |
| Yoshida, T | 1 |
3 other studies available for ebselen and Myocardial Ischemia
| Article | Year |
|---|---|
Age- and chamber-specific differences in oxidative stress after ischemic injury.
Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Catalase; Heart Ventricles; Hydrogen Peroxide; Isoi | 2012 |
Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction.
Topics: Animals; Azoles; Blood Pressure; Constriction; Coronary Circulation; Coronary Vessels; Disease Model | 1994 |
Oxidative stress developed during open heart surgery induces apoptosis: reduction of apoptotic cell death by ebselen, a glutathione peroxidase mimic.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Azoles; Creatine Kinase; DNA Fragmentation; | 2000 |