ebselen has been researched along with Metabolic Syndrome in 2 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with Ebselen partially prevented the decrease in capillary density and angiogenic competence of renal explants, and restored acetylcholine-induced vasorelaxation in 22-week-old ZDF rats." | 1.32 | Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen. ( Brodsky, SV; Chander, PN; Friedli, C; Gealekman, O; Goligorsky, MS; Nasjletti, A; Zhang, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kagota, S | 1 |
| Maruyama, K | 1 |
| Tada, Y | 1 |
| Fukushima, K | 1 |
| Umetani, K | 1 |
| Wakuda, H | 1 |
| Shinozuka, K | 1 |
| Gealekman, O | 1 |
| Brodsky, SV | 1 |
| Zhang, F | 1 |
| Chander, PN | 1 |
| Friedli, C | 1 |
| Nasjletti, A | 1 |
| Goligorsky, MS | 1 |
2 other studies available for ebselen and Metabolic Syndrome
| Article | Year |
|---|---|
Chronic oxidative-nitrosative stress impairs coronary vasodilation in metabolic syndrome model rats.
Topics: Animals; Azoles; Coronary Vessels; Cyclic N-Oxides; Disease Models, Animal; Down-Regulation; Free Ra | 2013 |
Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen.
Topics: Acetylcholine; Animals; Antioxidants; Azoles; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dis | 2004 |