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ebselen and Ischemic Attack, Transient

ebselen has been researched along with Ischemic Attack, Transient in 3 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"Ebselen treatment diminished the cytochrome c release at 12 and 24 hours."1.31Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. ( Kikuchi, H; Masayasu, H; Nagata, I; Namura, S; Takami, S, 2001)
"Twenty-five dogs were exposed to subarachnoid hemorrhage and divided into two groups."1.30Ebselen (DR3305) ameliorates delayed cerebral vasospasm in a canine two-hemorrhage model. ( Asano, T; Hori, T; Masayasu, H; Nishiyama, M; Shimizu, T; Watanabe, T, 1997)
"Ebselen was given through a gastric tube 30 min before occlusion in the experimental groups."1.30Effects of ebselen on cerebral ischemia and reperfusion evaluated by microdialysis. ( Kajimoto, S; Kawanishi, M; Kondoh, S; Nagasawa, S; Ohta, T; Yamaguchi, K, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, T1
Nishiyama, M1
Hori, T1
Asano, T1
Shimizu, T1
Masayasu, H2
Kondoh, S1
Nagasawa, S1
Kawanishi, M1
Yamaguchi, K1
Kajimoto, S1
Ohta, T1
Namura, S1
Nagata, I1
Takami, S1
Kikuchi, H1

Other Studies

3 other studies available for ebselen and Ischemic Attack, Transient

ArticleYear
Ebselen (DR3305) ameliorates delayed cerebral vasospasm in a canine two-hemorrhage model.
    Neurological research, 1997, Volume: 19, Issue:5

    Topics: Animals; Arachidonate 5-Lipoxygenase; Azoles; Basilar Artery; Dogs; Hydroxyeicosatetraenoic Acids; I

1997
Effects of ebselen on cerebral ischemia and reperfusion evaluated by microdialysis.
    Neurological research, 1999, Volume: 21, Issue:7

    Topics: Animals; Antioxidants; Azoles; Cerebral Cortex; Ischemic Attack, Transient; Isoindoles; Lactates; La

1999
Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice.
    Stroke, 2001, Volume: 32, Issue:8

    Topics: Animals; Apoptosis; Azoles; Blotting, Western; Brain; Caspase 3; Caspases; Cell Survival; Cytochrome

2001
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