ebselen has been researched along with Iron Overload in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic iron overload is a major cause of cardiac failure throughout the world, but its pathogenesis remains to be clarified." | 1.32 | Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice. ( Bartfay, WJ; Davis, MT, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rhee, JW | 1 |
| Yi, H | 1 |
| Thomas, D | 1 |
| Lam, CK | 1 |
| Belbachir, N | 1 |
| Tian, L | 1 |
| Qin, X | 1 |
| Malisa, J | 1 |
| Lau, E | 1 |
| Paik, DT | 1 |
| Kim, Y | 1 |
| Choi, BS | 1 |
| Sayed, N | 1 |
| Sallam, K | 1 |
| Liao, R | 1 |
| Wu, JC | 1 |
| Kumfu, S | 1 |
| Chattipakorn, S | 1 |
| Fucharoen, S | 1 |
| Chattipakorn, N | 1 |
| Davis, MT | 1 |
| Bartfay, WJ | 1 |
3 other studies available for ebselen and Iron Overload
| Article | Year |
|---|---|
Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Topics: Arrhythmias, Cardiac; Azoles; Calcium; Cardiomyopathies; Cell Line; Electrophysiological Phenomena; | 2020 |
Ferric iron uptake into cardiomyocytes of β-thalassemic mice is not through calcium channels.
Topics: Animals; Azoles; beta-Thalassemia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-T | 2013 |
Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice.
Topics: Animals; Antioxidants; Azoles; Cardiomyopathies; Chronic Disease; Cyclooxygenase Inhibitors; Disease | 2004 |