ebselen and Intracranial Aneurysm studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

Excerpt	Relevance	Reference
"The effect of ebselen, a seleno-organic compound with antioxidant activity through a glutathione peroxidase-like action, on the outcome of subarachnoid hemorrhage was evaluated in a multicenter placebo-controlled double-blind clinical trial."	9.08	Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. ( Abe, H; Asano, T; Ishibashi, S; Kikuchi, H; Ohta, T; Saito, I; Sano, K; Takakura, K; Yoshimoto, T, 1998)
"The effect of ebselen, a seleno-organic compound with antioxidant activity through a glutathione peroxidase-like action, on the outcome of subarachnoid hemorrhage was evaluated in a multicenter placebo-controlled double-blind clinical trial."	5.08	Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. ( Abe, H; Asano, T; Ishibashi, S; Kikuchi, H; Ohta, T; Saito, I; Sano, K; Takakura, K; Yoshimoto, T, 1998)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

ebselen and Intracranial Aneurysm

Research Excerpts

Research

Studies (1)

Authors

Trials

Authors	Studies
Saito, I	1
Asano, T	1
Sano, K	1
Takakura, K	1
Abe, H	1
Yoshimoto, T	1
Kikuchi, H	1
Ohta, T	1
Ishibashi, S	1