ebselen has been researched along with Infarction, Middle Cerebral Artery in 4 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with ebselen, which induced significant (P < 0." | 5.32 | Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. ( Alborch, E; Burguete, MC; Marín, N; Pérez-Asensio, FJ; Pitarch, C; Romero, FJ; Salom, JB; Torregrosa, G, 2004) |
| "Pretreatment with ebselen, which induced significant (P < 0." | 1.32 | Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. ( Alborch, E; Burguete, MC; Marín, N; Pérez-Asensio, FJ; Pitarch, C; Romero, FJ; Salom, JB; Torregrosa, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Zhang, J | 1 |
| Chen, L | 1 |
| Xing, S | 1 |
| Li, J | 1 |
| Zhang, Y | 1 |
| Li, C | 1 |
| Pei, Z | 1 |
| Zeng, J | 1 |
| Wong, CH | 1 |
| Bozinovski, S | 1 |
| Hertzog, PJ | 1 |
| Hickey, MJ | 1 |
| Crack, PJ | 1 |
| Salom, JB | 1 |
| Pérez-Asensio, FJ | 1 |
| Burguete, MC | 1 |
| Marín, N | 1 |
| Pitarch, C | 1 |
| Torregrosa, G | 1 |
| Romero, FJ | 1 |
| Alborch, E | 1 |
| Imai, H | 1 |
| Masayasu, H | 1 |
| Dewar, D | 1 |
| Graham, DI | 1 |
| Macrae, IM | 1 |
4 other studies available for ebselen and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Ebselen reduces autophagic activation and cell death in the ipsilateral thalamus following focal cerebral infarction.
Topics: Animals; Antioxidants; Autophagy; Azoles; Cell Death; Cerebral Infarction; Gliosis; Infarction, Midd | 2015 |
Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion.
Topics: Animals; Antioxidants; Azoles; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Disea | 2008 |
Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia.
Topics: Administration, Oral; Animals; Azoles; Body Weight; Brain; Brain Chemistry; Brain Ischemia; Drug Adm | 2004 |
Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia.
Topics: Animals; Antioxidants; Axons; Azoles; Brain; Brain Ischemia; Disease Models, Animal; DNA Damage; Inf | 2001 |