ebselen has been researched along with Gastric Ulcer in 4 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Excerpt | Relevance | Reference |
---|---|---|
"Pretreatment with ebselen at oral doses from 10 to 100 mg/kg significantly inhibited such lesion formation induced by either necrotizing agent in a dose-related manner, and the inhibition at the highest dose (100 mg/kg p." | 1.28 | Gastric cytoprotection by ebselen against the injury induced by necrotizing agents in rats. ( Akasaki, M; Kurebayashi, Y; Tabuchi, Y, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ohta, Y | 2 |
Kobayashi, T | 2 |
Inui, K | 1 |
Yoshino, J | 2 |
Nakazawa, S | 1 |
Kurebayashi, Y | 1 |
Tabuchi, Y | 1 |
Akasaki, M | 1 |
Parnham, MJ | 1 |
Biedermann, J | 1 |
Bittner, C | 1 |
Dereu, N | 1 |
Leyck, S | 1 |
Wetzig, H | 1 |
4 other studies available for ebselen and Gastric Ulcer
Article | Year |
---|---|
Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.
Topics: Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Azoles; Dose-Response Relationship, | 2002 |
Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80.
Topics: Animals; Anti-Ulcer Agents; Azoles; Gastric Mucosa; Glutathione Peroxidase; Histamine; Isoindoles; L | 2001 |
Gastric cytoprotection by ebselen against the injury induced by necrotizing agents in rats.
Topics: Animals; Antioxidants; Azoles; Ethanol; Gastric Mucosa; Indomethacin; Isoindoles; Male; Necrosis; Or | 1989 |
Structure-activity relationships of a series of anti-inflammatory benzisoselenazolones (BISAs).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Edema; Glutathion | 1989 |