Page last updated: 2024-10-26

ebselen and Gastric Ulcer

ebselen has been researched along with Gastric Ulcer in 4 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with ebselen at oral doses from 10 to 100 mg/kg significantly inhibited such lesion formation induced by either necrotizing agent in a dose-related manner, and the inhibition at the highest dose (100 mg/kg p."1.28Gastric cytoprotection by ebselen against the injury induced by necrotizing agents in rats. ( Akasaki, M; Kurebayashi, Y; Tabuchi, Y, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohta, Y2
Kobayashi, T2
Inui, K1
Yoshino, J2
Nakazawa, S1
Kurebayashi, Y1
Tabuchi, Y1
Akasaki, M1
Parnham, MJ1
Biedermann, J1
Bittner, C1
Dereu, N1
Leyck, S1
Wetzig, H1

Other Studies

4 other studies available for ebselen and Gastric Ulcer

ArticleYear
Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.
    Japanese journal of pharmacology, 2002, Volume: 90, Issue:4

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Azoles; Dose-Response Relationship,

2002
Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80.
    European journal of pharmacology, 2001, Mar-02, Volume: 414, Issue:2-3

    Topics: Animals; Anti-Ulcer Agents; Azoles; Gastric Mucosa; Glutathione Peroxidase; Histamine; Isoindoles; L

2001
Gastric cytoprotection by ebselen against the injury induced by necrotizing agents in rats.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:2

    Topics: Animals; Antioxidants; Azoles; Ethanol; Gastric Mucosa; Indomethacin; Isoindoles; Male; Necrosis; Or

1989
Structure-activity relationships of a series of anti-inflammatory benzisoselenazolones (BISAs).
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Edema; Glutathion

1989