ebselen has been researched along with Edema in 6 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo, ebselen is a weak oral inhibitor of carrageenan paw oedema and adjuvant arthritis in the rat, differentiating it from classical NSAIDs such as indomethacin and diclofenac." | 7.67 | Ebselen: a new approach to the inhibition of peroxide-dependent inflammation. ( Kuhl, P; Leyck, S; Parnham, MJ; Schalkwijk, J; van den Berg, WB, 1987) |
| "Ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one), a seleno-organic compound with glutathione peroxidase-like activity in vitro, was compared with indomethacin, BW 755C, and levamisole as an inhibitor of carrageenan- and CVF (cobra venom factor)-induced paw oedema in the rat." | 3.68 | Acute antiinflammatory and gastric effects of the seleno-organic compound ebselen. ( Leyck, S; Parnham, MJ, 1990) |
| " In vivo, ebselen is a weak oral inhibitor of carrageenan paw oedema and adjuvant arthritis in the rat, differentiating it from classical NSAIDs such as indomethacin and diclofenac." | 3.67 | Ebselen: a new approach to the inhibition of peroxide-dependent inflammation. ( Kuhl, P; Leyck, S; Parnham, MJ; Schalkwijk, J; van den Berg, WB, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lulla, A | 1 |
| Reznik, S | 1 |
| Trombetta, L | 1 |
| Billack, B | 1 |
| Nakamura, Y | 1 |
| Feng, Q | 1 |
| Kumagai, T | 1 |
| Torikai, K | 1 |
| Ohigashi, H | 1 |
| Osawa, T | 1 |
| Noguchi, N | 1 |
| Niki, E | 1 |
| Uchida, K | 1 |
| Leyck, S | 3 |
| Parnham, MJ | 3 |
| Biedermann, J | 1 |
| Bittner, C | 1 |
| Dereu, N | 1 |
| Wetzig, H | 1 |
| Kuhl, P | 1 |
| Schalkwijk, J | 1 |
| van den Berg, WB | 1 |
| Mercurio, SD | 1 |
| Combs, GF | 1 |
6 other studies available for ebselen and Edema
| Article | Year |
|---|---|
Use of the mouse ear vesicant model to evaluate the effectiveness of ebselen as a countermeasure to the nitrogen mustard mechlorethamine.
Topics: Administration, Cutaneous; Animals; Azoles; Dose-Response Relationship, Drug; Ear; Edema; Irritants; | 2014 |
Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis.
Topics: Animals; Antioxidants; Azoles; Blotting, Western; Carcinogens; Cell Line; Cells, Cultured; Cyclooxyg | 2002 |
Acute antiinflammatory and gastric effects of the seleno-organic compound ebselen.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1990 |
Structure-activity relationships of a series of anti-inflammatory benzisoselenazolones (BISAs).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Edema; Glutathion | 1989 |
Ebselen: a new approach to the inhibition of peroxide-dependent inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoles; Edema; Female; Indomethacin; Inflammation; | 1987 |
Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick.
Topics: Animals; Aurothioglucose; Azoles; Chickens; Edema; Glutathione Peroxidase; Isoindoles; Liver; NADP; | 1986 |