ebselen has been researched along with Diabetic Angiopathies in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress." | 3.76 | Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse. ( Chew, P; Cooper, ME; Coughlan, MT; de Haan, JB; Jandeleit-Dahm, KA; Pete, J; Rosenfeldt, F; Stefanovic, N; Thomas, MC; Yuen, DY, 2010) |
| " Current evidence suggests that a more nuanced approach to antioxidant therapy is more likely to yield positive reductions in end-organ injury, with considerations required for the types of ROS/RNS involved, the timing and dosage of antioxidant therapy, and the selective targeting of cell populations." | 2.52 | Are reactive oxygen species still the basis for diabetic complications? ( de Haan, JB; Di Marco, E; Jandeleit-Dahm, KA; Jha, JC; Sharma, A; Wilkinson-Berka, JL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Marco, E | 1 |
| Jha, JC | 1 |
| Sharma, A | 1 |
| Wilkinson-Berka, JL | 1 |
| Jandeleit-Dahm, KA | 2 |
| de Haan, JB | 3 |
| Chew, P | 2 |
| Yuen, DY | 2 |
| Koh, P | 1 |
| Stefanovic, N | 2 |
| Febbraio, MA | 1 |
| Kola, I | 1 |
| Cooper, ME | 2 |
| Pete, J | 1 |
| Coughlan, MT | 1 |
| Thomas, MC | 1 |
| Rosenfeldt, F | 1 |
1 review available for ebselen and Diabetic Angiopathies
| Article | Year |
|---|---|
Are reactive oxygen species still the basis for diabetic complications?
Topics: Animals; Antioxidants; Azoles; Blood Vessels; Diabetic Angiopathies; Diabetic Nephropathies; Diabeti | 2015 |
2 other studies available for ebselen and Diabetic Angiopathies
| Article | Year |
|---|---|
Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Apo | 2009 |
Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse.
Topics: Aldehydes; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Azoles; Diabetes Mellitus, Exp | 2010 |