ebselen has been researched along with Degenerative Diseases, Central Nervous System in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen is a synthetic organoselenium radical scavenger compound that possesses glutathione peroxidase-like activity and its own unique bioactivity by reacting with thiols, hydroperoxides and peroxynitrites." | 2.66 | Mechanisms of ebselen as a therapeutic and its pharmacology applications. ( Dong, C; Wang, J; Wang, P; Yuan, C; Zhao, Y; Zhou, J; Zou, L, 2020) |
| "Ebselen is a selenium compound that have glutathione peroxidase-like activity which is neuroprotective in acute stroke ischemia." | 1.31 | Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons. ( Boeck, CR; Porciúncula, LO; Rocha, JB; Souza, DO; Vendite, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Wang, P | 1 |
| Dong, C | 1 |
| Zhao, Y | 1 |
| Zhou, J | 1 |
| Yuan, C | 1 |
| Zou, L | 1 |
| Sharma, G | 1 |
| Shin, EJ | 1 |
| Sharma, N | 1 |
| Nah, SY | 1 |
| Mai, HN | 1 |
| Nguyen, BT | 1 |
| Jeong, JH | 1 |
| Lei, XG | 1 |
| Kim, HC | 1 |
| Porciúncula, LO | 1 |
| Rocha, JB | 1 |
| Boeck, CR | 1 |
| Vendite, D | 1 |
| Souza, DO | 1 |
2 reviews available for ebselen and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Mechanisms of ebselen as a therapeutic and its pharmacology applications.
Topics: Animals; Azoles; Bipolar Disorder; Cardiovascular Diseases; Hearing Loss, Sensorineural; Humans; Imm | 2020 |
Glutathione peroxidase-1 and neuromodulation: Novel potentials of an old enzyme.
Topics: Animals; Azoles; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Infrared Rays; Isoindo | 2021 |
1 other study available for ebselen and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons.
Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Cell Survival; Cells, Cultured; Cerebellar Cortex; | 2001 |