Page last updated: 2024-10-26

ebselen and Clostridium Infections

ebselen has been researched along with Clostridium Infections in 2 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Clostridium Infections: Infections with bacteria of the genus CLOSTRIDIUM and closely related CLOSTRIDIOIDES species.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Garland, M2
Hryckowian, AJ2
Tholen, M1
Bender, KO2
Van Treuren, WW1
Loscher, S1
Sonnenburg, JL2
Bogyo, M2
Ferreyra, JA1
Child, MA1
Puri, AW1
Solow-Cordero, DE1
Higginbottom, SK1
Segal, E1
Banaei, N1
Shen, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised, Parallel Group, Double Blind, Placebo Controlled, Add on Clinical Trial to Investigate Whether the Lithium Mimetic, Ebselen, Can Reduce Symptoms of Hypomania and Mania in Bipolar Patients[NCT03013400]Phase 260 participants (Actual)Interventional2017-10-01Completed
Phase 1b Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of SPI-1005 in Meniere's Disease[NCT02603081]Phase 1/Phase 240 participants (Actual)Interventional2015-12-31Completed
Signaling Mechanisms and Vascular Function in Patients With Diabetes Mellitus[NCT00762671]Phase 2/Phase 360 participants (Actual)Interventional1999-05-31Completed
A Phase 1, Double-blind, Placebo-controled, Randomized Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SPI-1005 (Ebselen)in Healthy Adult Subjects[NCT01452607]Phase 132 participants (Actual)Interventional2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for ebselen and Clostridium Infections

ArticleYear
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.
    Cell reports. Medicine, 2020, 04-21, Volume: 1, Issue:1

    Topics: Animals; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dysbi

2020
A small-molecule antivirulence agent for treating Clostridium difficile infection.
    Science translational medicine, 2015, Sep-23, Volume: 7, Issue:306

    Topics: Animals; Anti-Bacterial Agents; Azoles; Clostridioides difficile; Clostridium Infections; Isoindoles

2015