ebselen has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "LFB staining was used to detect demyelination." | 1.91 | Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice. ( Cheng, B; Dong, F; Liu, Y; Meng, Q; Song, X; Yan, W; Yao, R, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, F | 1 |
| Yan, W | 1 |
| Meng, Q | 1 |
| Song, X | 1 |
| Cheng, B | 1 |
| Liu, Y | 1 |
| Yao, R | 1 |
| Mazzanti, CM | 2 |
| Spanevello, R | 1 |
| Ahmed, M | 2 |
| Pereira, LB | 1 |
| Gonçalves, JF | 2 |
| Corrêa, M | 1 |
| Schmatz, R | 1 |
| Stefanello, N | 1 |
| Leal, DB | 1 |
| Mazzanti, A | 2 |
| Ramos, AT | 1 |
| Martins, TB | 1 |
| Danesi, CC | 1 |
| Graça, DL | 2 |
| Morsch, VM | 2 |
| Schetinger, MR | 2 |
| Spanevello, RM | 1 |
| Morsch, A | 1 |
| Zanin, R | 1 |
| Battisti, V | 1 |
3 other studies available for ebselen and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice.
Topics: Animals; Brain Ischemia; Carotid Stenosis; Cognition; Cognitive Dysfunction; Demyelinating Diseases; | 2023 |
Pre-treatment with ebselen and vitamin E modulate acetylcholinesterase activity: interaction with demyelinating agents.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Antioxidants; Azoles; Brain; Cholinergic Fibers; Demye | 2009 |
Previous treatment with ebselen and vitamin E alters adenine nucleotide hydrolysis in platelets from adult rats experimentally demyelinated with ethidium bromide.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Trip | 2007 |