ebselen has been researched along with Chronic Disease in 2 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The monkeys were randomly divided into three groups according to Ebselen dosage: 1) no dosage or non-treated group; 2) high-dose Ebselen group; and 3) low-dose Ebselen group." | 5.31 | Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. ( Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Takeuchi, H; Tsuchida, A, 2000) |
| "Chronic iron overload is a major cause of cardiac failure throughout the world, but its pathogenesis remains to be clarified." | 1.32 | Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice. ( Bartfay, WJ; Davis, MT, 2004) |
| " The monkeys were randomly divided into three groups according to Ebselen dosage: 1) no dosage or non-treated group; 2) high-dose Ebselen group; and 3) low-dose Ebselen group." | 1.31 | Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. ( Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Takeuchi, H; Tsuchida, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MT | 1 |
| Bartfay, WJ | 1 |
| Handa, Y | 1 |
| Kaneko, M | 1 |
| Takeuchi, H | 1 |
| Tsuchida, A | 1 |
| Kobayashi, H | 1 |
| Kubota, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Aneurysms: a Retrospective Study on the Experience in Our Hospital With a Comparative Analysis Between the Different Techniques Used in Its Treatment[NCT04792944] | 247 participants (Actual) | Observational | 2007-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for ebselen and Chronic Disease
| Article | Year |
|---|---|
Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice.
Topics: Animals; Antioxidants; Azoles; Cardiomyopathies; Chronic Disease; Cyclooxygenase Inhibitors; Disease | 2004 |
Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates.
Topics: Animals; Antioxidants; Azoles; Cerebral Angiography; Chronic Disease; Dose-Response Relationship, Dr | 2000 |