ebselen and Choline Deficiency studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

Research Excerpts

Excerpt	Relevance	Reference
"This study evaluated the effects of the seleno-organic substance Ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one] in two models of acute hemorrhagic and acute edematous pancreatitis."	7.68	Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. ( Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K, 1991)
"This study evaluated the effects of the seleno-organic substance Ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one] in two models of acute hemorrhagic and acute edematous pancreatitis."	3.68	Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. ( Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K, 1991)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

ebselen and Choline Deficiency

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Niederau, C	1
Ude, K	1
Niederau, M	1
Lüthen, R	1
Strohmeyer, G	1
Ferrell, LD	1
Grendell, JH	1