Page last updated: 2024-10-26

ebselen and Cardiomyopathies

ebselen has been researched along with Cardiomyopathies in 3 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Daunorubicin is an anthracycline antitumour agent that can cause severe cardiomyopathy leading to a frequently fatal congestive heart failure."1.33Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. ( Arafah, MM; Najjar, TA; Saad, SY, 2006)
"Chronic iron overload is a major cause of cardiac failure throughout the world, but its pathogenesis remains to be clarified."1.32Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice. ( Bartfay, WJ; Davis, MT, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Rhee, JW1
Yi, H1
Thomas, D1
Lam, CK1
Belbachir, N1
Tian, L1
Qin, X1
Malisa, J1
Lau, E1
Paik, DT1
Kim, Y1
Choi, BS1
Sayed, N1
Sallam, K1
Liao, R1
Wu, JC1
Davis, MT1
Bartfay, WJ1
Saad, SY1
Najjar, TA1
Arafah, MM1

Other Studies

3 other studies available for ebselen and Cardiomyopathies

ArticleYear
Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Cell reports, 2020, 07-14, Volume: 32, Issue:2

    Topics: Arrhythmias, Cardiac; Azoles; Calcium; Cardiomyopathies; Cell Line; Electrophysiological Phenomena;

2020
Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice.
    Biological research for nursing, 2004, Volume: 6, Issue:1

    Topics: Animals; Antioxidants; Azoles; Cardiomyopathies; Chronic Disease; Cyclooxygenase Inhibitors; Disease

2004
Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Aspartate Aminotransferases; Azoles; Cardiomyopa

2006