ebselen has been researched along with Carcinoma, Squamous Cell in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, using HNSCC cell lines, we examined the anti-cancer effects and the mechanisms of action of docosahexaenoyl ethanolamide (DHEA) and N-arachidonoyl-L-alanine (NALA), which are polyunsaturated fatty acid (PUFA)-based ethanolamides like AEA." | 1.43 | 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells. ( Hah, JH; Jeong, WJ; Oh, SM; Park, SW; Sung, MW, 2016) |
| " Following a 24-hour incubation of a toxic concentration of CEES (1000 μmol L-1), we used the MTT [3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide] test to analyse cell viability." | 1.39 | Ebselen analogues reduce 2-chloroethyl ethyl sulphide toxicity in A-431 cells. ( Billack, B; Pietka-Ottlik, M; Pino, MA, 2013) |
| " While generally less toxic than sulfur mustards, these compounds have the potential for use as chemical warfare agents." | 1.34 | Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity. ( Billack, B; Hardej, D, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pino, MA | 1 |
| Pietka-Ottlik, M | 1 |
| Billack, B | 2 |
| Park, SW | 1 |
| Hah, JH | 1 |
| Oh, SM | 1 |
| Jeong, WJ | 1 |
| Sung, MW | 1 |
| Hardej, D | 1 |
3 other studies available for ebselen and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Ebselen analogues reduce 2-chloroethyl ethyl sulphide toxicity in A-431 cells.
Topics: Antioxidants; Azoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemical Warfare Ag | 2013 |
5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells.
Topics: Alanine; Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Azoles; B | 2016 |
Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity.
Topics: Animals; Astrocytes; Azoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemical War | 2007 |