ebselen has been researched along with Carcinoma, Hepatocellular in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen analogues were also more effective antiviral agents, and they were less toxic to hepatocytes than ebselen." | 5.40 | Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication. ( Frick, DN; Hanson, AM; Isailovic, D; Kolli, R; Marvin, RK; Mukherjee, S; Ndjomou, J; Schoenen, FJ; Schroeder, CE; Simpson, DS; Sweeney, NL; Weiner, WS, 2014) |
| "Ebselen analogues were also more effective antiviral agents, and they were less toxic to hepatocytes than ebselen." | 1.40 | Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication. ( Frick, DN; Hanson, AM; Isailovic, D; Kolli, R; Marvin, RK; Mukherjee, S; Ndjomou, J; Schoenen, FJ; Schroeder, CE; Simpson, DS; Sweeney, NL; Weiner, WS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mukherjee, S | 1 |
| Weiner, WS | 1 |
| Schroeder, CE | 1 |
| Simpson, DS | 1 |
| Hanson, AM | 1 |
| Sweeney, NL | 1 |
| Marvin, RK | 1 |
| Ndjomou, J | 1 |
| Kolli, R | 1 |
| Isailovic, D | 1 |
| Schoenen, FJ | 1 |
| Frick, DN | 1 |
| Shaaban, S | 1 |
| Ashmawy, AM | 1 |
| Negm, A | 1 |
| Wessjohann, LA | 1 |
| Yang, CF | 1 |
| Shen, HM | 1 |
| Ong, CN | 1 |
3 other studies available for ebselen and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.
Topics: Antioxidants; Antiviral Agents; Azoles; Carcinoma, Hepatocellular; Cell Proliferation; Electrophoret | 2014 |
Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma.
Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Breast Neoplasms; Carcinoma, Hepatocellular | 2019 |
Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols.
Topics: Antioxidants; Apoptosis; Azoles; Carcinoma, Hepatocellular; Cell Survival; Glutathione; Humans; In S | 2000 |