ebselen has been researched along with Brain Injuries in 2 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen treatment significantly ameliorated the neurological injury of TBI rats in a dose-dependent manner." | 1.40 | Neuroprotective effects of ebselen in traumatic brain injury model: involvement of nitric oxide and p38 mitogen-activated protein kinase signalling pathway. ( Sun, Z; Wang, Q; Wei, L; Yang, C; Zhang, Y; Zhuang, Z, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, L | 1 |
| Zhang, Y | 1 |
| Yang, C | 1 |
| Wang, Q | 1 |
| Zhuang, Z | 1 |
| Sun, Z | 1 |
| Jean Harry, G | 1 |
| Bruccoleri, A | 1 |
| Lefebvre d'Hellencourt, C | 1 |
2 other studies available for ebselen and Brain Injuries
| Article | Year |
|---|---|
Neuroprotective effects of ebselen in traumatic brain injury model: involvement of nitric oxide and p38 mitogen-activated protein kinase signalling pathway.
Topics: Animals; Azoles; Blotting, Western; Brain Injuries; Disease Models, Animal; Dose-Response Relationsh | 2014 |
Differential modulation of hippocampal chemical-induced injury response by ebselen, pentoxifylline, and TNFalpha-, IL-1alpha-, and IL-6-neutralizing antibodies.
Topics: Animals; Antibodies; Azoles; Brain Injuries; Cerebellum; Cytokines; Disease Models, Animal; Drug Com | 2003 |