Page last updated: 2024-10-26

ebselen and Body Weight

ebselen has been researched along with Body Weight in 8 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" We sought to investigate whether long-term administration of seleno-glutathione peroxidase mimic ebselen (PZ51) would have a protective effect on cortical neurons in SHRsp, and, if so, the possible mechanisms of this effect."5.33Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005)
"Pretreatment with ebselen, which induced significant (P < 0."5.32Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. ( Alborch, E; Burguete, MC; Marín, N; Pérez-Asensio, FJ; Pitarch, C; Romero, FJ; Salom, JB; Torregrosa, G, 2004)
"To investigate whether extrinsic antioxidant seleno-glutathione peroxidase mimic ebselen (PZ51) can protect endothelium and vascular structure of stroke-prone spontaneously hypertensive rats (SHRsp) during the chronic process of hypertension."3.73Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005)
" We sought to investigate whether long-term administration of seleno-glutathione peroxidase mimic ebselen (PZ51) would have a protective effect on cortical neurons in SHRsp, and, if so, the possible mechanisms of this effect."1.33Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005)
"Pretreatment with ebselen, which induced significant (P < 0."1.32Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. ( Alborch, E; Burguete, MC; Marín, N; Pérez-Asensio, FJ; Pitarch, C; Romero, FJ; Salom, JB; Torregrosa, G, 2004)
" Therefore, the long-term administration of ebselen might be expected to induce an immunocompromised state in the host."1.29Susceptibility of mice to bacterial and fungal infections after intragastric administration of ebselen. ( Arai, M; Kuruto, R; Masayasu, H; Motohashi, T; Nozawa, R, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Yerbury, JJ1
Cashman, NR1
Mahadevan, J1
Parazzoli, S1
Oseid, E1
Hertzel, AV1
Bernlohr, DA1
Vallerie, SN1
Liu, CQ1
Lopez, M1
Harmon, JS1
Robertson, RP1
Salom, JB1
Pérez-Asensio, FJ1
Burguete, MC1
Marín, N1
Pitarch, C1
Torregrosa, G1
Romero, FJ1
Alborch, E1
Sui, H2
Wang, W2
Wang, PH2
Liu, LS2
Nozawa, R1
Arai, M1
Kuruto, R1
Motohashi, T1
Masayasu, H1
Kono, H1
Arteel, GE1
Rusyn, I1
Sies, H1
Thurman, RG1
Pritsos, CA1
Sokoloff, M1
Gustafson, DL1

Other Studies

8 other studies available for ebselen and Body Weight

ArticleYear
Selenium-based compounds: Emerging players in the ever-unfolding story of SOD1 in amyotrophic lateral sclerosis.
    EBioMedicine, 2020, Volume: 59

    Topics: Amyotrophic Lateral Sclerosis; Animals; Azoles; Body Weight; Disease Models, Animal; Humans; Isoindo

2020
Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves β-cell mass and function in ZDF rats.
    Diabetes, 2013, Volume: 62, Issue:10

    Topics: Adipocytes; Animals; Antioxidants; Apoptosis; Azoles; Blood Glucose; Body Weight; Cell Differentiati

2013
Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia.
    European journal of pharmacology, 2004, Jul-08, Volume: 495, Issue:1

    Topics: Administration, Oral; Animals; Azoles; Body Weight; Brain; Brain Chemistry; Brain Ischemia; Drug Adm

2004
Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:3

    Topics: Animals; Antioxidants; Azoles; Blood Pressure; Blotting, Western; Body Weight; Cerebral Cortex; Hype

2005
Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats.
    Blood pressure, 2005, Volume: 14, Issue:6

    Topics: Animals; Antioxidants; Azoles; Blood Pressure; Blotting, Western; Body Weight; Carotid Arteries; End

2005
Susceptibility of mice to bacterial and fungal infections after intragastric administration of ebselen.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Body Weight; Calcitriol; Candidiasis; Carc

1996
Ebselen prevents early alcohol-induced liver injury in rats.
    Free radical biology & medicine, 2001, Feb-15, Volume: 30, Issue:4

    Topics: Alanine Transaminase; Aldehydes; Animals; Antioxidants; Azoles; Body Weight; Enteral Nutrition; Etha

2001
PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity.
    Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Azoles; Body Weight; Chemical and Drug Induced Liver Injury;

1992