ebselen has been researched along with Astrocytoma, Grade IV in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the pro-inflammatory response mediated by TNFalpha in glioblastoma and whether treatment with organoselenium Ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]one) can affect TNFalpha induced inflammatory response." | 7.75 | Ebselen abrogates TNFalpha induced pro-inflammatory response in glioblastoma. ( Ghosh, A; Hossain Sk, U; Joseph, C; Koul, N; Sen, E; Sharma, V; Tewari, R, 2009) |
| "Cotreatment with Ebselen and TNFalpha induced G2/M phase arrest in cell cycle and modulated the expression of molecules involved in cell cycle progression." | 5.35 | Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex. ( Joseph, C; Sen, E; Sharma, V; Sk, UH; Tewari, R, 2008) |
| "We investigated the pro-inflammatory response mediated by TNFalpha in glioblastoma and whether treatment with organoselenium Ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]one) can affect TNFalpha induced inflammatory response." | 3.75 | Ebselen abrogates TNFalpha induced pro-inflammatory response in glioblastoma. ( Ghosh, A; Hossain Sk, U; Joseph, C; Koul, N; Sen, E; Sharma, V; Tewari, R, 2009) |
| "Cotreatment with Ebselen and TNFalpha induced G2/M phase arrest in cell cycle and modulated the expression of molecules involved in cell cycle progression." | 1.35 | Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex. ( Joseph, C; Sen, E; Sharma, V; Sk, UH; Tewari, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dukhande, VV | 1 |
| Kawikova, I | 1 |
| Bothwell, AL | 1 |
| Lai, JC | 1 |
| Sharma, V | 2 |
| Tewari, R | 2 |
| Sk, UH | 1 |
| Joseph, C | 2 |
| Sen, E | 2 |
| Koul, N | 1 |
| Ghosh, A | 1 |
| Hossain Sk, U | 1 |
3 other studies available for ebselen and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.
Topics: Apoptosis; Azoles; bcl-2-Associated X Protein; Buthionine Sulfoximine; Cell Line, Tumor; Cell Surviv | 2013 |
Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex.
Topics: Apoptosis; Azoles; Cell Cycle; Cell Line, Tumor; Down-Regulation; fas Receptor; Fas-Associated Death | 2008 |
Ebselen abrogates TNFalpha induced pro-inflammatory response in glioblastoma.
Topics: Azoles; Cell Movement; DNA Repair; Gene Expression Regulation; Glioblastoma; Humans; Inflammation; I | 2009 |