ebselen has been researched along with Alloxan Diabetes in 11 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen was subsequently evaluated in MRSA-infected PUs in two models using obese and diabetic mice." | 5.62 | Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice. ( Abutaleb, NS; Dieterly, AM; Lyle, LT; Mohammad, H; Seleem, MN, 2021) |
| "To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress." | 3.76 | Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse. ( Chew, P; Cooper, ME; Coughlan, MT; de Haan, JB; Jandeleit-Dahm, KA; Pete, J; Rosenfeldt, F; Stefanovic, N; Thomas, MC; Yuen, DY, 2010) |
| "Ebselen was subsequently evaluated in MRSA-infected PUs in two models using obese and diabetic mice." | 1.62 | Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice. ( Abutaleb, NS; Dieterly, AM; Lyle, LT; Mohammad, H; Seleem, MN, 2021) |
| "Diabetic retinopathy is the primary cause of blindness in developed countries, and though strict glycemic control is desirable to prevent complications, this is not always achievable." | 1.32 | [Oxidative stress in a model for experimental diabetic retinopathy: treatment with antioxidants]. ( Araiz, J; Bosch-Morell, F; Johnsen, S; Miranda, M; Muriach, M; Romá, J; Romero, FJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Polianskyte-Prause, Z | 1 |
| Tolvanen, TA | 1 |
| Lindfors, S | 1 |
| Kon, K | 1 |
| Hautala, LC | 1 |
| Wang, H | 1 |
| Wada, T | 1 |
| Tsuneki, H | 1 |
| Sasaoka, T | 1 |
| Lehtonen, S | 1 |
| Mohammad, H | 1 |
| Abutaleb, NS | 1 |
| Dieterly, AM | 1 |
| Lyle, LT | 1 |
| Seleem, MN | 1 |
| Mahadevan, J | 1 |
| Parazzoli, S | 1 |
| Oseid, E | 1 |
| Hertzel, AV | 1 |
| Bernlohr, DA | 1 |
| Vallerie, SN | 1 |
| Liu, CQ | 1 |
| Lopez, M | 1 |
| Harmon, JS | 1 |
| Robertson, RP | 1 |
| Tan, SM | 1 |
| Sharma, A | 1 |
| Yuen, DY | 3 |
| Stefanovic, N | 3 |
| Krippner, G | 1 |
| Mugesh, G | 1 |
| Chai, Z | 1 |
| de Haan, JB | 3 |
| Chew, P | 2 |
| Koh, P | 1 |
| Febbraio, MA | 1 |
| Kola, I | 1 |
| Cooper, ME | 2 |
| Pete, J | 1 |
| Coughlan, MT | 1 |
| Jandeleit-Dahm, KA | 1 |
| Thomas, MC | 1 |
| Rosenfeldt, F | 1 |
| Miranda, M | 1 |
| Muriach, M | 1 |
| Johnsen, S | 1 |
| Bosch-Morell, F | 1 |
| Araiz, J | 1 |
| Romá, J | 1 |
| Romero, FJ | 1 |
| Barbosa, NB | 1 |
| Rocha, JB | 1 |
| Wondracek, DC | 1 |
| Perottoni, J | 1 |
| Zeni, G | 1 |
| Nogueira, CW | 1 |
| Bubolz, AH | 1 |
| Wu, Q | 1 |
| Larsen, BT | 1 |
| Gutterman, DD | 1 |
| Liu, Y | 1 |
| Chen, J | 1 |
| Brodsky, SV | 1 |
| Goligorsky, DM | 1 |
| Hampel, DJ | 1 |
| Li, H | 1 |
| Gross, SS | 1 |
| Goligorsky, MS | 1 |
| Flechner, I | 1 |
| Maruta, K | 1 |
| Burkart, V | 1 |
| Kawai, K | 1 |
| Kolb, H | 1 |
| Kiesel, U | 1 |
11 other studies available for ebselen and Alloxan Diabetes
| Article | Year |
|---|---|
Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Inflammation; Insulin; Insulin Resistance; Isoindoles; Mic | 2022 |
Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice.
Topics: Animals; Anti-Bacterial Agents; Azoles; Diabetes Mellitus, Experimental; Disease Models, Animal; Iso | 2021 |
Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves β-cell mass and function in ZDF rats.
Topics: Adipocytes; Animals; Antioxidants; Apoptosis; Azoles; Blood Glucose; Body Weight; Cell Differentiati | 2013 |
The modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Azoles; Cell Line; Diabetes Mellitus, Experimental; Dia | 2013 |
Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Apo | 2009 |
Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse.
Topics: Aldehydes; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Azoles; Diabetes Mellitus, Exp | 2010 |
[Oxidative stress in a model for experimental diabetic retinopathy: treatment with antioxidants].
Topics: Animals; Antioxidants; Azoles; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Isoindoles; Lu | 2004 |
Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.
Topics: Alanine Transaminase; Aminolevulinic Acid; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotran | 2006 |
Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats.
Topics: Adenylyl Cyclases; Animals; Antioxidants; Azoles; Colforsin; Coronary Vessels; Cyclic AMP; Diabetes | 2007 |
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.
Topics: Animals; Apoptosis; Arginine; Azoles; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Coll | 2002 |
Effects of radical scavengers on the development of experimental diabetes.
Topics: Aging; Animals; Antioxidants; Azoles; Benzamides; Blood Glucose; Butylated Hydroxyanisole; Cysteamin | 1990 |