ebselen has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arsenic (As) exposure is associated with adverse health outcomes to the living organisms." | 1.62 | Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat. ( Abdel Moneim, AE; Al Aboud, D; Alsharif, KF; Amin, HK; Baty, RS; Elmahallawy, EK; Habotta, OA; Hassan, KE; Kassab, RB; Zhery, AS, 2021) |
| "Only ebselen was given to the rats in group 4." | 1.39 | Effects of ebselen on radiocontrast media-induced hepatotoxicity in rats. ( Akin, M; Basarslan, F; Davarci, I; Ozgur, M; Ulutas, KT; Yilmaz, C; Yilmaz, N, 2013) |
| " Here we report the potential toxic effects of diphenyl diselenide (PhSe)(2), diphenyl ditelluride (PhTe)(2) and Ebselen in rats and mice." | 1.32 | Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice. ( Borges, VC; Meotti, FC; Nogueira, CW; Rocha, JB; Zeni, G, 2003) |
| "Ebselen is a seleno-organic compound that inhibits oxidative stress by lipid peroxidation through a glutathione peroxidase-like activity." | 1.31 | Ebselen protects against the reduction in levels of drug-metabolizing enzymes in livers of rats with deoxycholic acid-induced liver injury. ( Kobayashi, S; Kumai, T; Matsumoto, N; Nakaya, S; Takezawa, N; Tanaka, M; Watanabe, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Al Aboud, D | 1 |
| Baty, RS | 1 |
| Alsharif, KF | 1 |
| Hassan, KE | 1 |
| Zhery, AS | 1 |
| Habotta, OA | 1 |
| Elmahallawy, EK | 1 |
| Amin, HK | 1 |
| Abdel Moneim, AE | 1 |
| Kassab, RB | 1 |
| Basarslan, F | 1 |
| Yilmaz, N | 1 |
| Davarci, I | 1 |
| Akin, M | 1 |
| Ozgur, M | 1 |
| Yilmaz, C | 1 |
| Ulutas, KT | 1 |
| Tanaka, M | 1 |
| Takezawa, N | 1 |
| Kumai, T | 1 |
| Watanabe, M | 1 |
| Matsumoto, N | 1 |
| Nakaya, S | 1 |
| Kobayashi, S | 1 |
| Meotti, FC | 1 |
| Borges, VC | 1 |
| Zeni, G | 1 |
| Rocha, JB | 1 |
| Nogueira, CW | 1 |
| Pritsos, CA | 1 |
| Sokoloff, M | 1 |
| Gustafson, DL | 1 |
| Parnham, MJ | 1 |
| Konz, KH | 1 |
| Tiegs, G | 2 |
| Wendel, A | 2 |
1 review available for ebselen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Biological activities and clinical potential of Ebselen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azoles; Chemical and Drug Induced Li | 1990 |
8 other studies available for ebselen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat.
Topics: Animals; Antioxidants; Arsenic; Azoles; Benzoquinones; Chemical and Drug Induced Liver Injury; Femal | 2021 |
Effects of ebselen on radiocontrast media-induced hepatotoxicity in rats.
Topics: Animals; Antioxidants; Azoles; Catalase; Chemical and Drug Induced Liver Injury; Contrast Media; Glu | 2013 |
Ebselen protects against the reduction in levels of drug-metabolizing enzymes in livers of rats with deoxycholic acid-induced liver injury.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Azoles; Chemical and Drug Induced | 2002 |
Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Benzene Derivatives; Blood Urea | 2003 |
PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity.
Topics: Acetylcysteine; Animals; Antioxidants; Azoles; Body Weight; Chemical and Drug Induced Liver Injury; | 1992 |
Protection by ebselen against endotoxin shock in rats or mice sensitized by galactosamine.
Topics: Animals; Azoles; Chemical and Drug Induced Liver Injury; Fatty Acids, Unsaturated; Galactosamine; Gl | 1987 |
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver | 1986 |